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Strategic transactions and agreements - Other asset acquisitions and license agreements (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Dec. 31, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
In-process research and development $ 0 $ 6,706 $ 0 $ 124,972  
Other asset acquisitions and license agreements          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Accrued expenses and other current liabilities         $ 1,200
Upfront consideration paid in cash   $ 4,000   $ 10,300