Collaboration agreement with AbbVie - Change in deferred revenue (Details) - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Deferral of revenue			$ (6,941,000)	$ (6,303,000)
Recognition of revenue	$ 0	$ (2,910,000)	(6,941,000)	(6,303,000)
Collaboration agreement with AbbVie
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Beginning balance			6,941,000
Deferral of revenue			0
Recognition of revenue	0	$ (2,900,000)	(6,941,000)	$ (6,300,000)
Balance at the end of the period	$ 0		$ 0