X0202 SCHEDULE 13G/A 0001425738 XXXXXXXX LIVE 4 Common Stock, $0.0001 par value per share 03/31/2026 0001472012 Immunome, Inc. 45257U108 18702 N. Creek Parkway, Suite 100 Bothell WA 98011 Rule 13d-1(b) Redmile Group, LLC DE 0.00 5558885.00 0.00 5558885.00 5558885.00 N 4.9 IA OO The information in Item 4 relating to the shares of the Issuer's common stock ("Common Stock") that are or may be deemed beneficially owned by Redmile Group, LLC ("Redmile") is incorporated herein by reference. Percentage based on 113,133,199 shares of Common Stock outstanding as of February 27, 2026, as reported by the Issuer in its Form 10-K for the fiscal year ended December 31, 2025 filed with the SEC on March 3, 2026 (the "Form 10-K"). Jeremy C. Green X0 0.00 5558885.00 0.00 5558885.00 5558885.00 N 4.9 HC IN The information in Item 4 relating to the shares of Common Stock that are or may be deemed beneficially owned by Jeremy C. Green is incorporated herein by reference. Percentage based on 113,133,199 shares of Common Stock outstanding as of February 27, 2026, as reported by the Issuer in the Form 10-K. Immunome, Inc. 18702 N. Creek Parkway, Suite 100, Bothell, WA 98011 Redmile Group, LLC Jeremy C. Green Redmile Group, LLC 900 Larkspur Landing Circle, Suite 270 Larkspur, California 94939 Jeremy C. Green c/o Redmile Group, LLC (NY Office) 45 W. 27th Street, Floor 11 New York, NY 10001 Redmile Group, LLC: Delaware Jeremy C. Green: United Kingdom N IA HC Redmile Group, LLC - 5,558,885 (1) Jeremy C. Green - 5,558,885 (1) Redmile Group, LLC - 4.9% (2) Jeremy C. Green - 4.9% (2) Redmile Group, LLC - 0 Jeremy C. Green - 0 Redmile Group, LLC - 5,558,885 (1) Jeremy C. Green - 5,558,885 (1) Redmile Group, LLC - 0 Jeremy C. Green - 0 Redmile Group, LLC - 5,558,885 (1) Jeremy C. Green - 5,558,885 (1) (1) As of March 31, 2026, Redmile's and Jeremy C. Green's beneficial ownership of Common Stock is comprised of 5,558,885 shares of Common Stock. All of such shares of Common Stock are directly owned by certain investment vehicles for which Redmile is the investment manager (the "Redmile Funds"). Redmile may be deemed to beneficially own these securities in its capacity as the investment manager with discretion to vote and dispose of all shares of Common Stock held by the Redmile Funds. Mr. Green also may be deemed to beneficially own these securities as the principal of Redmile. Redmile and Mr. Green each disclaim beneficial ownership of these securities, except to the extent of its or his pecuniary interest in such securities, if any. (2) Percentage based on 113,133,199 shares of Common Stock outstanding as of February 27, 2026, as reported by the Issuer in the Form 10-K. N Y Y N See the response to Item 4. Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Redmile Group, LLC /s/ Jeremy C. Green 05/15/2026 Jeremy C. Green /s/ Jeremy C. Green 05/15/2026