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Condensed Consolidated Statements of Changes in Stockholders Equity - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-in Capital
Accumulated Other Comprehensive Income
Accumulated Deficit
Zentalis Asset Purchase Agreement
Zentalis Asset Purchase Agreement
Common Stock
Zentalis Asset Purchase Agreement
Additional Paid-in Capital
Ayala Asset Purchase Agreement
Ayala Asset Purchase Agreement
Common Stock
Ayala Asset Purchase Agreement
Additional Paid-in Capital
ATM
Balance at Dec. 31, 2023 $ 119,882 $ 4 $ 342,663 $ 22 $ (222,807)              
Balance (in shares) at Dec. 31, 2023   43,251,778                    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Share-based compensation expense 2,159   2,159                  
Issuance of common stock 215,410 $ 2 215,408     $ 23,388   $ 23,388 $ 50,645   $ 50,645  
Issuance of common stock (in shares)   11,500,000         2,298,586     2,175,489    
Exercise of stock options 171   171                  
Exercise of stock options (in shares)   125,704                    
Exercise of common stock warrants 3,427   3,427                  
Exercise of common stock warrants (in shares)   342,686                    
Unrealized loss on marketable securities (18)     (18)                
Net loss (129,492)       (129,492)              
Balance at Mar. 31, 2024 285,572 $ 6 637,861 4 (352,299)              
Balance (in shares) at Mar. 31, 2024   59,694,243                    
Balance at Dec. 31, 2023 119,882 $ 4 342,663 22 (222,807)              
Balance (in shares) at Dec. 31, 2023   43,251,778                    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Net loss (165,614)                      
Balance at Jun. 30, 2024 253,838 $ 6 642,251 2 (388,421)              
Balance (in shares) at Jun. 30, 2024   60,013,655                    
Balance at Mar. 31, 2024 285,572 $ 6 637,861 4 (352,299)              
Balance (in shares) at Mar. 31, 2024   59,694,243                    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Share-based compensation expense 3,227   3,227                  
Exercise of stock options 859   859                  
Exercise of stock options (in shares)   289,041                    
Exercise of common stock warrants 304   304                  
Exercise of common stock warrants (in shares)   30,371                    
Unrealized loss on marketable securities (2)     (2)                
Net loss (36,122)       (36,122)              
Balance at Jun. 30, 2024 253,838 $ 6 642,251 2 (388,421)              
Balance (in shares) at Jun. 30, 2024   60,013,655                    
Balance at Dec. 31, 2024 181,165 $ 6 696,872 57 (515,770)              
Balance (in shares) at Dec. 31, 2024   64,460,829                    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Share-based compensation expense 5,703   5,703                  
Issuance of common stock 161,745 $ 3 161,742                  
Issuance of common stock (in shares)   22,258,064                    
Exercise of stock options 213   213                  
Exercise of stock options (in shares)   236,962                    
Unrealized loss on marketable securities (60)     (60)                
Net loss (41,640)       (41,640)              
Balance at Mar. 31, 2025 307,126 $ 9 864,530 (3) (557,410)              
Balance (in shares) at Mar. 31, 2025   86,955,855                    
Balance at Dec. 31, 2024 $ 181,165 $ 6 696,872 57 (515,770)              
Balance (in shares) at Dec. 31, 2024   64,460,829                    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Issuance of common stock (in shares)                       0
Exercise of stock options (in shares) 313,035                      
Net loss $ (85,037)                      
Balance at Jun. 30, 2025 269,270 $ 9 870,092 (24) (600,807)              
Balance (in shares) at Jun. 30, 2025   87,012,835                    
Balance at Mar. 31, 2025 307,126 $ 9 864,530 (3) (557,410)              
Balance (in shares) at Mar. 31, 2025   86,955,855                    
Increase (Decrease) in Stockholders' Equity [Roll Forward]                        
Share-based compensation expense 5,347   5,347                  
Exercise of stock options 215   215                  
Exercise of stock options (in shares)   56,980                    
Unrealized loss on marketable securities (21)     (21)                
Net loss (43,397)       (43,397)              
Balance at Jun. 30, 2025 $ 269,270 $ 9 $ 870,092 $ (24) $ (600,807)              
Balance (in shares) at Jun. 30, 2025   87,012,835