X0202 SCHEDULE 13G/A 0000902664-25-000645 0001603466 XXXXXXXX LIVE 1 Common Stock, par value $0.0001 per share 03/31/2026 0001472012 Immunome Inc. 45257U108 18702 N. Creek Parkway Suite 100 Bothell WA 98011 Rule 13d-1(c) Point72 Asset Management, L.P. b DE 0.00 0.00 0.00 0.00 0.00 N 0 PN Point72 Capital Advisors, Inc. b DE 0.00 0.00 0.00 0.00 0.00 N 0 CO Steven A. Cohen b X1 0.00 0.00 0.00 0.00 0.00 N 0 IN Immunome Inc. 18702 N. Creek Parkway, Suite 100, Bothell, WA 98011 This statement is filed by: (i) Point72 Asset Management, L.P. ("Point72 Asset Management") with respect to the shares of common stock, par value $0.0001 per share ("Shares"), of Immunome, Inc. that were held by an investment fund it manages; (ii) Point72 Capital Advisors, Inc. ("Point72 Capital Advisors Inc.") with respect to Shares that were held by an investment fund managed by Point72 Asset Management; and (iii) Steven A. Cohen ("Mr. Cohen") with respect to Shares that were beneficially owned by Point72 Asset Management and Point72 Capital Advisors Inc. The address of the principal business office of Point72 Asset Management, Point72 Capital Advisors Inc., and Mr. Cohen is 72 Cummings Point Road, Stamford, CT 06902. Point72 Asset Management is a Delaware limited partnership. Point72 Capital Advisors Inc. is a Delaware corporation. Mr. Cohen is a United States citizen. Y The information required by Item 4(a) is set forth in Row 9 of the cover page for each of the Reporting Persons and is incorporated herein by reference. Such information is as of the close of business on March 31, 2026. 0% The information required by Item 4(c)(i) is set forth in Row 5 of the cover page for each of the Reporting Persons and is incorporated herein by reference. Such information is as of the close of business on March 31, 2026. The information required by Item 4(c)(ii) is set forth in Row 6 of the cover page for each of the Reporting Persons and is incorporated herein by reference. Such information is as of the close of business on March 31, 2026. The information required by Item 4(c)(iii) is set forth in Row 7 of the cover page for each of the Reporting Persons and is incorporated herein by reference. Such information is as of the close of business on March 31, 2026. The information required by Item 4(c)(iv) is set forth in Row 8 of the cover page for each of the Reporting Persons and is incorporated herein by reference. Such information is as of the close of business on March 31, 2026. N Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Point72 Asset Management, L.P. /s/ Jason M. Colombo 05/15/2026 Point72 Capital Advisors, Inc. /s/ Jason M. Colombo 05/15/2026 Steven A. Cohen /s/ Jason M. Colombo 05/15/2026