X0407 4 2023-03-17 0 0000850261 Sorrento Therapeutics, Inc. SRNEQ 0001470981 Ji Henry C/O SORRENTO THERAPEUTICS, INC. 4955 DIRECTORS PLACE SAN DIEGO CA 92121 1 1 0 0 See Remarks 0 Common Stock 2023-03-17 4 X 0 19500 0.8027 A 20000 I By BioVintage, Inc. Common Stock 6265805 D Common Stock 2271693 I See Footnote Common Stock 40000 I By spouse Put Option (obligation to buy) 0.8027 2023-03-17 4 D 0 195 0.00 D 2022-08-26 2023-03-17 Common Stock 19500 0 I By BioVintage, Inc. On December 30, 2022, the Issuer's Board of Directors declared a stock dividend (the "Dividend") to all holders of record of its common stock as of the close of business on January 9, 2023, of 0.1410127 of a share of common stock, par value $0.0001 per share, of Scilex Holding Company ("Scilex Common Stock") for each one share of common stock, par value $0.0001 per share, of the Issuer ("Sorrento Common Stock"). The Put Option written by the Reporting Person on August 26, 2022 (the "Put Option") was previously reported at an exercise price of $5.50 per share of Sorrento Common Stock, which was adjusted as a result of the Dividend to relate to an aggregate of 19,500 shares of Sorrento Common Stock and 2,730 shares of Scilex Common Stock and to reflect a corresponding change to the exercise price of the Put Option to $0.80268 per share of Sorrento Common Stock and $8.6002 per share of Scilex Common Stock. The Put Option settled on March 17, 2023 and resulted in the Reporting Person (Continued Footnote 1) acquiring 19,500 shares of Sorrento Common Stock at a price of $0.80268 per share of Sorrento Common Stock, in addition to 2,730 shares of Scilex Common Stock at a price of $8.6002 per share of Scilex Common Stock. Shares are held in family trusts of which the Reporting Person is a co-trustee with his spouse. President, CEO and Chairman of the Board of Directors /s/ Henry Ji, Ph.D. 2023-03-20