<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0704</schemaVersion>

    <submissionType>D/A</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001470174</cik>
        <entityName>Lighthouse Global Long/Short Fund Ltd</entityName>
        <issuerAddress>
            <street1>45 MARKET STREET, SUITE 3205, 2ND FL</street1>
            <street2>GARDENIA COURT, CAMANA BAY</street2>
            <city>GRAND CAYMAN</city>
            <stateOrCountry>E9</stateOrCountry>
            <stateOrCountryDescription>CAYMAN ISLANDS</stateOrCountryDescription>
            <zipCode>KY1-9003</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>3459467412</issuerPhoneNumber>
        <jurisdictionOfInc>CAYMAN ISLANDS</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Other</entityType>
        <entityTypeOtherDesc>exempted company</entityTypeOtherDesc>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>(LLC)</firstName>
                <lastName>Lighthouse Investment Partners LLC</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>3801 PGA Blvd.</street1>
                <street2>Suite 500</street2>
                <city>Palm Beach Gardens</city>
                <stateOrCountry>FL</stateOrCountry>
                <stateOrCountryDescription>FLORIDA</stateOrCountryDescription>
                <zipCode>33410</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification>investment manager</relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>(SPC)</firstName>
                <lastName>LMA SPC</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>45 Market Street, Suite 3205, 2nd Floor</street1>
                <street2>Gardenia Court, Camana Bay</street2>
                <city>Grand Cayman</city>
                <stateOrCountry>E9</stateOrCountry>
                <stateOrCountryDescription>CAYMAN ISLANDS</stateOrCountryDescription>
                <zipCode>KY1-9003</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Promoter</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Sean</firstName>
                <middleName>G.</middleName>
                <lastName>McGould</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>3801 PGA Blvd.</street1>
                <street2>Suite 500</street2>
                <city>Palm Beach Gardens</city>
                <stateOrCountry>FL</stateOrCountry>
                <stateOrCountryDescription>FLORIDA</stateOrCountryDescription>
                <zipCode>33410</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Kelly</firstName>
                <middleName>R.</middleName>
                <lastName>Perkins</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>3801 PGA Blvd.</street1>
                <street2>Suite 500</street2>
                <city>Palm Beach Gardens</city>
                <stateOrCountry>FL</stateOrCountry>
                <stateOrCountryDescription>FLORIDA</stateOrCountryDescription>
                <zipCode>33410</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Robert</firstName>
                <middleName>P.</middleName>
                <lastName>Swan, III</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>3801 PGA Blvd.</street1>
                <street2>Suite 500</street2>
                <city>Palm Beach Gardens</city>
                <stateOrCountry>FL</stateOrCountry>
                <stateOrCountryDescription>FLORIDA</stateOrCountryDescription>
                <zipCode>33410</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>J.</firstName>
                <middleName>Scott</middleName>
                <lastName>Perkins</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>3801 PGA Blvd.</street1>
                <street2>Suite 500</street2>
                <city>Palm Beach Gardens</city>
                <stateOrCountry>FL</stateOrCountry>
                <stateOrCountryDescription>FLORIDA</stateOrCountryDescription>
                <zipCode>33410</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pooled Investment Fund</industryGroupType>
            <investmentFundInfo>
                <investmentFundType>Hedge Fund</investmentFundType>
                <is40Act>false</is40Act>
            </investmentFundInfo>
        </industryGroup>
        <issuerSize>
            <aggregateNetAssetValueRange>Decline to Disclose</aggregateNetAssetValueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
            <item>3C</item>
            <item>3C.7</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>true</isAmendment>
                <previousAccessionNumber>0001470173-09-000006</previousAccessionNumber>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2004-01-01</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>true</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isPooledInvestmentFundType>true</isPooledInvestmentFundType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>50000</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>Atlantic Trust Company</recipientName>
                <recipientCRDNumber>None</recipientCRDNumber>
                <associatedBDName>Atlantic Trust Company</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>50 Rockefeller Plaza</street1>
                    <street2>15th Floor</street2>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>10020</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
            <recipient>
                <recipientName>JP Morgan Securities, Inc.</recipientName>
                <recipientCRDNumber>79</recipientCRDNumber>
                <associatedBDName>JP Morgan Securities, Inc.</associatedBDName>
                <associatedBDCRDNumber>79</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>383 Madison Avenue</street1>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>10179</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
            <recipient>
                <recipientName>Ounavarra Capital, LLC</recipientName>
                <recipientCRDNumber>143381</recipientCRDNumber>
                <associatedBDName>Ounavarra Capital, LLC</associatedBDName>
                <associatedBDCRDNumber>143381</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>410 Park Avenue</street1>
                    <street2>Suite 510</street2>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>10022</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
            <recipient>
                <recipientName>Suntrust Banks, Inc.</recipientName>
                <recipientCRDNumber>17499</recipientCRDNumber>
                <associatedBDName>Suntrust Banks, Inc.</associatedBDName>
                <associatedBDCRDNumber>17499</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>303 Peachtree Center Avenue</street1>
                    <street2>Suite 140</street2>
                    <city>Atlanta</city>
                    <stateOrCountry>GA</stateOrCountry>
                    <stateOrCountryDescription>GEORGIA</stateOrCountryDescription>
                    <zipCode>30303</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
            <recipient>
                <recipientName>Thomas Weisel Partners, LLC</recipientName>
                <recipientCRDNumber>46237</recipientCRDNumber>
                <associatedBDName>Thomas Weisel Partners, LLC</associatedBDName>
                <associatedBDCRDNumber>46237</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>390 Park Avenue</street1>
                    <street2>2nd Floor</street2>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>10022</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
            <recipient>
                <recipientName>UBS AG</recipientName>
                <recipientCRDNumber>None</recipientCRDNumber>
                <associatedBDName>UBS AG</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>101 Park Avenue</street1>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>10178</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
            <recipient>
                <recipientName>Capital Strategies Partners AV SA</recipientName>
                <recipientCRDNumber>None</recipientCRDNumber>
                <associatedBDName>Capital Strategies Partners AV SA</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>C/Joaquin Bau</street1>
                    <street2>7 3 I</street2>
                    <city>Madrid</city>
                    <stateOrCountry>U3</stateOrCountry>
                    <stateOrCountryDescription>SPAIN</stateOrCountryDescription>
                    <zipCode>28036</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
            <recipient>
                <recipientName>Credit Suisse</recipientName>
                <recipientCRDNumber>112892</recipientCRDNumber>
                <associatedBDName>Credit Suisse</associatedBDName>
                <associatedBDCRDNumber>112892</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>12 E. 49th Street</street1>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>10017</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
            <recipient>
                <recipientName>Deutsche Bank</recipientName>
                <recipientCRDNumber>2525</recipientCRDNumber>
                <associatedBDName>Deutsche Bank</associatedBDName>
                <associatedBDCRDNumber>2525</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>60 Wall Street</street1>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>100005</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
            <recipient>
                <recipientName>HFA Asset Management</recipientName>
                <recipientCRDNumber>None</recipientCRDNumber>
                <associatedBDName>HFA Asset Management</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>Level 5</street1>
                    <street2>151 Macquarie Street</street2>
                    <city>Sydney</city>
                    <stateOrCountry>C3</stateOrCountry>
                    <stateOrCountryDescription>AUSTRALIA</stateOrCountryDescription>
                    <zipCode>NSW 2000</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
            <recipient>
                <recipientName>Sunrise Securities Corp.</recipientName>
                <recipientCRDNumber>29804</recipientCRDNumber>
                <associatedBDName>Sunrise Securities Corp.</associatedBDName>
                <associatedBDCRDNumber>29804</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>641 Lexington Avenue</street1>
                    <street2>25th Floor</street2>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>10022</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <value>All States</value>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>Indefinite</totalOfferingAmount>
            <totalAmountSold>0</totalAmountSold>
            <totalRemaining>Indefinite</totalRemaining>
            <clarificationOfResponse>Unable to determine without unreasonable time and effort, based on amount of redemptions, reinvestments and life of fund.</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>57</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
                <isEstimate>true</isEstimate>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
                <isEstimate>true</isEstimate>
            </findersFees>
            <clarificationOfResponse>Placement agents may receive up front commissions of up to 3% of amount invested in fund. In addition, the fund's investment manager may pay a portion of it's management fees to certain finders.</clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
                <isEstimate>true</isEstimate>
            </grossProceedsUsed>
            <clarificationOfResponse>*For its services to the fund the investment manager is entitled to a monthly management fee, paid in arrears that may range up to 1.5% in some cases.</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Lighthouse Global Long/Short Fund Ltd</issuerName>
                <signatureName>J. Scott Perkins</signatureName>
                <nameOfSigner>J. Scott Perkins</nameOfSigner>
                <signatureTitle>EMD, Lighthouse Investment Partners LLC, Investment Manager</signatureTitle>
                <signatureDate>2010-05-12</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
