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Share Based Awards (Details) - shares
3 Months Ended
Jan. 01, 2019
Mar. 31, 2020
Dec. 31, 2019
Jan. 05, 2016
Dec. 20, 2015
Share Based Compensation Arrangement By Share Based Payment Award          
Options granted, exercisable term   3 years 11 months 5 days      
Shares of common stock available for issuance   21,126,985 17,218,449    
Additional shares authorized   5,636,269      
2008 Stock Plan          
Share Based Compensation Arrangement By Share Based Payment Award          
Expiry term of exercisable options   10 years      
2014 Equity Incentive Plan          
Share Based Compensation Arrangement By Share Based Payment Award          
Shares of common stock, authorized for issuance   8,142,857      
Maximum annual percentage increase in shares issuable   5.00%      
Additional shares authorized 5,636,269        
Additional shares authorized as a percentage of common stock outstanding 5.00%        
Amended And Restated 2015 Inducement Plan [Member]          
Share Based Compensation Arrangement By Share Based Payment Award          
Shares of common stock, authorized for issuance         1,600,000
Shares of common stock available for issuance       1,970,000  
Shares outstanding under the 2015 Inducement Plan   690,625      
2014 Employee Stock Purchase Plan/ESPP          
Share Based Compensation Arrangement By Share Based Payment Award          
Shares of common stock available for issuance   943,545 378,525    
Maximum annual percentage increase in shares issuable   1.00%      
Additional shares authorized 1,127,253        
Additional shares authorized as a percentage of common stock outstanding 1.00%        
Maximum percentage of employee base compensation that may be utilized to purchase common stock under the ESPP   15.00%      
Percentage of purchase price of common stock at fair market value   85.00%      
Maximum increase in shares issuable   2,142,857      
Minimum | 2008 Stock Plan          
Share Based Compensation Arrangement By Share Based Payment Award          
Options granted, exercisable term   3 years      
Maximum | 2008 Stock Plan          
Share Based Compensation Arrangement By Share Based Payment Award          
Options granted, exercisable term   4 years      
Maximum | 2014 Equity Incentive Plan          
Share Based Compensation Arrangement By Share Based Payment Award          
Shares of common stock available for issuance   16,312,202