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Share Based Awards (Details) - shares
9 Months Ended
Jan. 01, 2019
Sep. 30, 2019
Dec. 31, 2018
Jan. 05, 2016
Dec. 20, 2015
Share Based Compensation Arrangement By Share Based Payment Award          
Options granted, exercisable term   4 years 5 months 23 days      
Shares of common stock available for issuance   18,479,011 19,502,777    
Additional shares authorized   5,310,327      
ESPP          
Share Based Compensation Arrangement By Share Based Payment Award          
Maximum percentage of employee base compensation that may be utilized to purchase common stock under the ESPP   15.00%      
Percentage of purchase price of common stock at fair market value   85.00%      
2008 Stock Plan          
Share Based Compensation Arrangement By Share Based Payment Award          
Expiry term of exercisable options   10 years      
2014 Equity Incentive Plan          
Share Based Compensation Arrangement By Share Based Payment Award          
Shares of common stock, authorized for issuance   8,142,857      
Maximum annual percentage increase in shares issuable   5.00%      
2014 Equity Incentive Plan | Incentive Stock Options          
Share Based Compensation Arrangement By Share Based Payment Award          
Additional shares authorized 5,310,327        
Additional shares authorized as a percentage of common stock outstanding 5.00%        
2015 Inducement Plan          
Share Based Compensation Arrangement By Share Based Payment Award          
Shares of common stock, authorized for issuance         1,600,000
Shares of common stock available for issuance       1,970,000  
2015 Inducement Plan | Incentive Stock Options          
Share Based Compensation Arrangement By Share Based Payment Award          
Shares outstanding under the 2015 Inducement Plan   778,125      
2015 Inducement Plan | Restricted stock units          
Share Based Compensation Arrangement By Share Based Payment Award          
Shares outstanding under the 2015 Inducement Plan   882,813      
2014 Employee Stock Purchase Plan/ESPP          
Share Based Compensation Arrangement By Share Based Payment Award          
Shares of common stock available for issuance   378,525 364,762    
Maximum annual percentage increase in shares issuable   1.00%      
Additional shares authorized 1,062,065        
Additional shares authorized as a percentage of common stock outstanding 1.00%        
Maximum increase in shares issuable   2,142,857      
2014 Employee Stock Purchase Plan/ESPP | ESPP          
Share Based Compensation Arrangement By Share Based Payment Award          
Shares of common stock available for issuance   378,525 364,762    
Minimum | 2008 Stock Plan          
Share Based Compensation Arrangement By Share Based Payment Award          
Options granted, exercisable term   3 years      
Maximum | 2008 Stock Plan          
Share Based Compensation Arrangement By Share Based Payment Award          
Options granted, exercisable term   4 years      
Maximum | 2014 Equity Incentive Plan          
Share Based Compensation Arrangement By Share Based Payment Award          
Shares of common stock available for issuance   16,312,202