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Stock-Based Compensation and Employee Stock Purchase Program - Weighted-Average Fair Value Assumption of Stock Option Awards (Detail) - Employee Stock Option [Member]
3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expected term (years) 6 years 10 months 2 days 7 years 8 months 8 days 6 years 4 months 13 days 6 years 6 months 25 days
Expected volatility 122.00% 112.00% 122.00% 119.00%
Risk-free interest rate 1.06% 0.54% 0.81% 1.12%