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Net Loss per Share - Summary of Securities Not Included in Diluted Per Share Calculations (Detail) - shares
6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities not included in the diluted per share calculations, amount 5,105,187 5,431,601
Option to purchase common stock [Member]    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities not included in the diluted per share calculations, amount 3,768,293 4,094,707
Warrants to purchase common stock [Member]    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities not included in the diluted per share calculations, amount 1,336,894 1,336,894