Stock-Based Compensation and Employee Stock Purchase Program (Tables)

3 Months Ended

12 Months Ended

Mar. 31, 2025

Dec. 31, 2024

Share-Based Payment Arrangement [Abstract]

Summary of Activity Under Stock Incentive Plans

The following is a summary of stock option information and weighted average exercise prices under the Company’s stock incentive plans:

	Shares Subject to Outstanding Options			Weighted- Average Exercise Price Per Share		Aggregate Intrinsic Value
Outstanding — Balance at December 31, 2024		205,475		$	21.00	$	516,378
Options expired		(13,964	)		98.37		—
Outstanding — Balance at March 31, 2025		191,511			14.92		40,820
Vested and expected to vest — March 31, 2025		177,989			15.82		37,420
Exercisable — March 31, 2025		29,741		$	79.12	$	—

The following is a summary of stock option information and weighted average exercise prices under the Company’s stock incentive plans (in thousands, except share data and price per share):

	Shares Subject to Outstanding Options			Weighted- Average Exercise Price Per Share		Aggregate Intrinsic Value
Outstanding — Balance at December 31, 2022		60,002		$	115	$	—
Options granted		26,021			6		—
Options exercised		—			—		—
Options forfeited		(5,644	)		30		39,062
Options expired		(301	)		121		—
Outstanding — Balance at December 31, 2023		80,078			85		—
Options granted		158,000			3		—
Options exercised		—			—		—
Options forfeited		(11,197	)		24		397
Options expired		(21,406	)		129		—
Outstanding — Balance at December 31, 2024		205,475			21		516,378
Vested and expected to vest — December 31, 2024		188,554			22		463,513
Exercisable —December 31, 2024		43,059		$	86	$	9,533

Weighted-Average Fair Value Assumption of Stock Option Awards

The fair value of stock option awards was estimated at the date of grant using the Black-Scholes option-pricing model with the following weighted-average assumption:

	Year Ended December 31,
Assumptions	2024			2023
Expected term (years)		8.04			7.06
Expected volatility		101	%		124	%
Risk-free interest rate		3.77	%		3.61	%
Expected dividend yield		—			—