Equity Financing - Additional Information (Detail)		1 Months Ended							12 Months Ended
	Aug. 16, 2022 USD ($) $ / shares	Aug. 31, 2022 USD ($) $ / shares shares	Jan. 31, 2021 USD ($) $ / shares shares	Dec. 31, 2020 USD ($) $ / shares shares	Sep. 30, 2019 USD ($) $ / shares shares	Jun. 30, 2019 USD ($) $ / shares shares	Jun. 30, 2018 USD ($) $ / shares shares	Mar. 31, 2018 USD ($) $ / shares shares	Dec. 31, 2022 USD ($)	Jun. 30, 2022 $ / shares	Jan. 28, 2021
Class Of Warrant Or Right [Line Items]
Stock price | $ / shares										$ 40.00
Maximum [Member]
Class Of Warrant Or Right [Line Items]
Proceeds from issuance, aggregate offering prices | $									$ 50,000,000.0
March 2018 Purchase Agreement [Member]
Class Of Warrant Or Right [Line Items]
Shares of common stock issued								30,041
Warrant issued, shares of common stock called by warrant								32,071
Warrants issued, exercise price | $ / shares								$ 429.03
August 2022 Purchase Agreement [Member]
Class Of Warrant Or Right [Line Items]
Shares of common stock issued		61,250
Offering closing period		Aug. 16, 2022
August 2022 Purchase Agreement [Member] | Pre Funded Warrants [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant		56,813
Warrants issued, exercise price | $ / shares		$ 0.004
August 2022 Purchase Agreement [Member] | Preferred Investment Options [Member]
Class Of Warrant Or Right [Line Items]
Shares of common stock issued		118,063
Exercise price | $ / shares		$ 37.35
Proceeds from issuance of common stock, pre-funded warrants and preferred investment options | $		$ 5,000,000.0
Warrants expiration period		5 years
December 2020 Purchase Agreement [Member]
Class Of Warrant Or Right [Line Items]
Shares of common stock issued				65,467
Proceeds from issuance of common stock and warrants gross | $				$ 8,000,000.0
Offering closing period				Dec. 22, 2020
December 2020 Purchase Agreement [Member] | Warrants [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant				65,467
Warrants issued, exercise price | $ / shares				$ 120.00
Warrants expiration period				5 years 6 months
September 2019 Purchase Agreement [Member]
Class Of Warrant Or Right [Line Items]
Shares of common stock issued					32,971
Proceeds from issuance of common stock and warrants gross | $					$ 10,000,000.0
Offering closing period					Sep. 05, 2019
September 2019 Purchase Agreement [Member] | Warrants [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant					16,486
Warrants issued, exercise price | $ / shares					$ 300.80
Warrants expiration period					5 years 6 months
June 2019 Purchase Agreement [Member]
Class Of Warrant Or Right [Line Items]
Shares of common stock issued						37,240
Proceeds from issuance of common stock and warrants gross | $						$ 7,500,000
Offering closing period						Jun. 14, 2019
June 2019 Purchase Agreement [Member] | Warrants [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant						37,240
Warrants issued, exercise price | $ / shares						$ 200.00
Warrants expiration period						5 years 6 months
June 2018 Purchase Agreement [Member]
Class Of Warrant Or Right [Line Items]
Shares of common stock issued							34,809
Proceeds from issuance of common stock and warrants gross | $							$ 14,000,000.0
Offering closing period							Jun. 14, 2018
June 2018 Purchase Agreement [Member] | Warrants [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant							34,809
Warrants issued, exercise price | $ / shares							$ 397.60
Warrants expiration period							5 years 6 months
June 2018 Placement Agent Warrants [Member] | June 2018 Purchase Agreement [Member] | Warrants [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant							1,741
Warrants issued, exercise price | $ / shares							$ 502.72
Warrant, exercisable term							5 years
June 2019 Placement Agent Warrants [Member] | June 2019 Purchase Agreement [Member] | Warrants [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant						1,862
Warrants issued, exercise price | $ / shares						$ 251.75
Warrant, exercisable term						5 years
September 2019 Placement Agent Warrants [Member] | September 2019 Purchase Agreement [Member] | Warrants [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant					1,649
Warrants issued, exercise price | $ / shares					$ 379.12
Warrant, exercisable term					5 years
August 2022 Options and August 2022 Placement Agent Options [Member]
Class Of Warrant Or Right [Line Items]
Expected volatility	128.46%
Stock price | $ / shares	$ 37.60
Risk-free interest rate	2.97%
Expected term	5 years
August 2022 Placement Agent Options [Member]
Class Of Warrant Or Right [Line Items]
Fair value assumptions, value | $	$ 191,000
Offering costs | $	488,000
Allocation of common stock option liability expense | $	314,000
Remaining offering costs allocated to common stock and offset to additional paid in capital | $	365,000
August 2022 Placement Agent Options [Member] | Warrants [Member]
Class Of Warrant Or Right [Line Items]
Offering costs | $	$ 679,000
August 2022 Placement Agent Options [Member] | August 2022 Purchase Agreement [Member] | Warrants [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant		5,904
Warrants issued, exercise price | $ / shares		$ 52.80
Warrant, exercisable term		5 years
December 2020 Placement Agent Warrants [Member] | December 2020 Purchase Agreement [Member] | Warrants [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant				3,274
Warrants issued, exercise price | $ / shares				$ 152.75
Warrant, exercisable term				5 years
January 2021 Private Placement [Member] | January 2021 Purchase Agreement [Member]
Class Of Warrant Or Right [Line Items]
Shares of common stock issued			196,920
Warrant issued, shares of common stock called by warrant			98,460
Warrants issued, exercise price | $ / shares			$ 125.20
Proceeds from issuance of common stock and warrants gross | $			$ 25,100,000
Warrants expiration period			5 years 6 months
Remaining offering costs allocated to common stock and offset to additional paid in capital | $			$ 2,000,000.0
January 2021 Private Placement [Member] | January 2021 Purchase Agreement [Member] | Warrants [Member]
Class Of Warrant Or Right [Line Items]
Offering costs allocated to common stock warrant liability and expensed | $			$ 769,000
January 2021 Private Placement [Member] | January 2021 Purchase Agreement [Member] | Warrants [Member] | Expected Volatility [Member]
Class Of Warrant Or Right [Line Items]
Preferred investment options liability, measurement input											1.238
January 2021 Private Placement [Member] | January 2021 Purchase Agreement [Member] | Warrants [Member] | Stock Price [Member]
Class Of Warrant Or Right [Line Items]
Preferred investment options liability, measurement input											1.1520
January 2021 Private Placement [Member] | January 2021 Purchase Agreement [Member] | Warrants [Member] | Risk-Free Interest Rate [Member]
Class Of Warrant Or Right [Line Items]
Preferred investment options liability, measurement input											0.05
January 2021 Private Placement [Member] | January 2021 Placement Agent Warrants [Member] | January 2021 Purchase Agreement [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant			9,846
Warrants issued, exercise price | $ / shares			$ 159.60
Offering costs | $			$ 1,900,000
Warrant, exercisable term			5 years 6 months
Issuance of placement agent warrants | $			$ 942,000
January 2021 Private Placement [Member] | January 2021 Placement Agent Warrants [Member] | January 2021 Purchase Agreement [Member] | Warrants [Member]
Class Of Warrant Or Right [Line Items]
Offering costs | $			$ 2,800,000
March 2018 Private Placement [Member] | March 2018 Purchase Agreement [Member]
Class Of Warrant Or Right [Line Items]
Shares of common stock issued								7,519
Warrant issued, shares of common stock called by warrant								7,519
Warrants issued, exercise price | $ / shares								$ 1,830.00
Proceeds from issuance of common stock and warrants gross | $								$ 10,000,000.0
Warrants expiration period								5 years
March 2018 Private Placement [Member] | March 2018 Placement Agent Warrants [Member] | March 2018 Purchase Agreement [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant								376
Warrants issued, exercise price | $ / shares								$ 1,662.50
Warrant, exercisable term								5 years