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Stock-Based Compensation and Employee Stock Purchase Program - Weighted-Average Fair Value Assumption of Stock Option Awards (Detail) - Employee Stock Option [Member]
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expected term (years) 5 years 8 months 8 days 6 years 29 days 6 years 4 months 28 days 6 years 4 months 2 days
Expected volatility 122.00% 121.00% 122.00% 122.00%
Risk-free interest rate 2.99% 0.97% 2.59% 0.83%
Dividend yield 0.00% 0.00% 0.00% 0.00%