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Stock-Based Compensation and Employee Stock Purchase Program - Weighted-Average Fair Value Assumption of Stock Option Awards (Detail) - Employee Stock Option [Member]
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Expected term (years) 6 years 29 days 6 years 10 days
Expected volatility 120.00% 121.00%
Risk-free interest rate 1.68% 0.62%