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Stock-Based Compensation and Employee Stock Purchase Program - Weighted-Average Fair Value Assumption of Stock Option Awards (Detail) - Employee Stock Option [Member]
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Expected term (years) 6 years 3 months 21 days 6 years 5 months 23 days
Expected volatility 121.00% 134.00%
Risk-free interest rate 0.86% 1.01%