<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2015-09-15</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001636519</issuerCik>
        <issuerName>MSG SPINCO, INC.</issuerName>
        <issuerTradingSymbol>NONE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001469372</rptOwnerCik>
            <rptOwnerName>Madison Square Garden Co</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>TWO PENNSYLVANIA PLAZA</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10121</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>See Remarks</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock, par value $0.01 per share</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Subsidiary</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The Madison Square Garden Company (&quot;MSG&quot;) may be deemed to beneficially own 1,000 shares of the common stock, par value $0.01 per share, of MSG Spinco, Inc. (&quot;MSG Spinco&quot;) indirectly through its wholly owned subsidiaries.  MSG Holdings, L.P. (&quot;MSG Holdings&quot;), an indirect wholly owned subsidiary of MSG, directly holds 1,000 shares of MSG Spinco common stock.  MSG Holdings is owned by MSGN Eden, LLC (0.32%) and Regional MSGN Holdings LLC (99.68%).  MSGN Eden, LLC is wholly owned by Rainbow Garden Corp., which is wholly owned by MSG.  Regional MSGN Holdings LLC is wholly owned by MSG.</footnote>
    </footnotes>

    <remarks>This Form 3 is being filed in connection with the Securities and Exchange Commission's declaration of effectiveness of the Registration Statement on Form 10 of MSG Spinco, which describes the planned distribution by MSG to its stockholders of all of the common stock of MSG Spinco.</remarks>

    <ownerSignature>
        <signatureName>/s/ Joseph F. Yospe, Senior Vice President, Controller and Principal Accounting Officer of The Madison Square Garden Company</signatureName>
        <signatureDate>2015-09-15</signatureDate>
    </ownerSignature>
</ownershipDocument>
