<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
		<previousAccessionNumber>0001415889-25-004092</previousAccessionNumber>
	    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001754181</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>




    </filerInfo>
  </headerData>

  <formData>
    <coverPageHeader>
		<amendmentNo>7</amendmentNo>
	      <securitiesClassTitle>Common Stock, $0.0001 par value per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>12/31/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001468748</issuerCik>        <issuerName>KODIAK SCIENCES INC.</issuerName>        <issuerCusip>50015M109</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>1250 PAGE MILL RD</com:street1>
                    <com:city>PALO ALTO</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94304</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>

	        <designateRulesPursuantThisScheduleFiled>
	           <designateRulePursuantThisScheduleFiled>Rule 13d-1(d)</designateRulePursuantThisScheduleFiled>
						      </designateRulesPursuantThisScheduleFiled>

    </coverPageHeader>

	    <coverPageHeaderReportingPersonDetails>




    <reportingPersonName>D. VICTOR PERLROTH, M.D.</reportingPersonName>



		 <citizenshipOrOrganization>X1</citizenshipOrOrganization>

      <reportingPersonBeneficiallyOwnedNumberOfShares>
                <soleVotingPower>6504427.00</soleVotingPower>
                          <sharedVotingPower>0.00</sharedVotingPower>
                          <soleDispositivePower>5977427.00</soleDispositivePower>
                         <sharedDispositivePower>0.00</sharedDispositivePower>
             </reportingPersonBeneficiallyOwnedNumberOfShares>

              <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>6504427.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>


     	    <classPercent>9.9</classPercent>










	        <typeOfReportingPerson>IN</typeOfReportingPerson>




    </coverPageHeaderReportingPersonDetails>

    <items>
      <item1>
        <issuerName>KODIAK SCIENCES INC.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>1250 PAGE MILL RD, PALO ALTO, CA, 94304.</issuerPrincipalExecutiveOfficeAddress>
      </item1>

      <item2>
        <filingPersonName>D. Victor Perlroth, M.D.</filingPersonName>        <principalBusinessOfficeOrResidenceAddress>c/o Kodiak Sciences Inc.
1250 Page Mill Road
Palo Alto, CA 94304</principalBusinessOfficeOrResidenceAddress>        <citizenship>United States</citizenship>      </item2>

        <item3>
		        <notApplicableFlag>Y</notApplicableFlag>

      </item3>



    <item4>
    <amountBeneficiallyOwned>Row 9 of the Reporting Person's cover page to this Schedule 13G sets forth the aggregate number of shares of Common Stock beneficially owned by the Reporting Person and is incorporated by reference. Row 9 includes (i) 2,095,538  shares of Common Stock held directly by Dr. Perlroth, (ii) 3,809,389 shares of Common Stock subject to options held by Dr. Perlroth that are immediately exercisable or exercisable within 60 days of December 31, 2025, including 658,919 shares of which are unvested and subject to an Issuer right of repurchase as of March 1, 2026, (iii) 72,500 shares of Common Stock held by the Perlroth Family Foundation U/A DTD 12/27/2006 for which Dr. Perlroth is a trustee, and (iv) 527,000 shares of Common Stock as to which Dr. Perlroth has sole voting power and no investment power pursuant to a voting agreement and proxy.</amountBeneficiallyOwned>    <classPercent>Row 11 of the Reporting Person's cover page to this Schedule 13G sets forth the percentage of the shares of securities of the Issuer beneficially owned by the Reporting Person as of December 31, 2025, and is incorporated by reference. The percentage set forth in Row 11 is based upon 61,758,454 shares of Common Stock outstanding as of December 31, 2025.</classPercent>
      <numberOfSharesPersonHas>
        <solePowerOrDirectToVote>6,504,427</solePowerOrDirectToVote>
        <sharedPowerOrDirectToVote>0</sharedPowerOrDirectToVote>
        <solePowerOrDirectToDispose>5,977,427</solePowerOrDirectToDispose>
        <sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
      </numberOfSharesPersonHas>
    </item4>


        <item5>
	          <notApplicableFlag>Y</notApplicableFlag>


    </item5>


        <item6>
	  	  <notApplicableFlag>Y</notApplicableFlag>
		        </item6>


        <item7>
	  	  <notApplicableFlag>Y</notApplicableFlag>


    </item7>


          <item8>
                <notApplicableFlag>Y</notApplicableFlag>

              </item8>


            <item9>
                <notApplicableFlag>Y</notApplicableFlag>
                      </item9>


      <item10>
                    <notApplicableFlag>Y</notApplicableFlag>

      </item10>
    </items>


	    <signatureInformation>
      <reportingPersonName>D. VICTOR PERLROTH, M.D.</reportingPersonName>

      <signatureDetails>
        <signature>/s/ D. Victor Perlroth</signature>
        <title>D. Victor Perlroth</title>
        <date>02/17/2026</date>
      </signatureDetails>

    </signatureInformation>



  </formData>

    </edgarSubmission>
