Condensed Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-In Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Beginning Balance at Dec. 31, 2020	$ 860,751	$ 5	$ 1,151,920	$ 53	$ (291,227)
Beginning balance, shares at Dec. 31, 2020		51,112,302
Issuance of common stock upon exercise of stock options	1,483		1,483
Issuance of common stock upon exercise of stock options, shares		113,559
Stock-based compensation expense	9,925		9,925
Other comprehensive loss	(35)			(35)
Net loss	(50,447)				(50,447)
Ending Balance at Mar. 31, 2021	821,677	$ 5	1,163,328	18	(341,674)
Ending balance, shares at Mar. 31, 2021		51,225,861
Beginning Balance at Dec. 31, 2020	860,751	$ 5	1,151,920	53	(291,227)
Beginning balance, shares at Dec. 31, 2020		51,112,302
Other comprehensive loss	(53)
Net loss	(106,299)
Ending Balance at Jun. 30, 2021	779,427	$ 5	1,176,948		(397,526)
Ending balance, shares at Jun. 30, 2021		51,434,408
Beginning Balance at Mar. 31, 2021	821,677	$ 5	1,163,328	18	(341,674)
Beginning balance, shares at Mar. 31, 2021		51,225,861
Issuance of common stock upon exercise of stock options	2,228		2,228
Issuance of common stock upon exercise of stock options, shares		131,276
Issuance of common stock upon vesting of restricted stock units, net of taxes withheld, shares		72,976
Issuance of common stock pursuant to employee stock purchase plans	305		305
Issuance of common stock pursuant to employee stock purchase plans, shares		4,295
Stock-based compensation expense	11,087		11,087
Other comprehensive loss	(18)			(18)
Net loss	(55,852)				(55,852)
Ending Balance at Jun. 30, 2021	779,427	$ 5	1,176,948		(397,526)
Ending balance, shares at Jun. 30, 2021		51,434,408
Beginning Balance at Dec. 31, 2021	663,320	$ 5	1,221,532		(558,217)
Beginning balance, shares at Dec. 31, 2021		51,826,257
Issuance of common stock upon exercise of stock options	1,678		1,678
Issuance of common stock upon exercise of stock options, shares		110,043
Issuance of common stock upon vesting of restricted stock units, net of taxes withheld, shares		3,581
Stock-based compensation expense	28,095		28,095
Net loss	(95,709)				(95,709)
Ending Balance at Mar. 31, 2022	597,384	$ 5	1,251,305		(653,926)
Ending balance, shares at Mar. 31, 2022		51,939,881
Beginning Balance at Dec. 31, 2021	663,320	$ 5	1,221,532		(558,217)
Beginning balance, shares at Dec. 31, 2021		51,826,257
Other comprehensive loss	(1,869)
Net loss	(186,337)
Ending Balance at Jun. 30, 2022	530,931	$ 5	1,277,349		(744,554)
Ending balance, shares at Jun. 30, 2022		52,024,621
Beginning Balance at Mar. 31, 2022	597,384	$ 5	1,251,305		(653,926)
Beginning balance, shares at Mar. 31, 2022		51,939,881
Issuance of common stock upon exercise of stock options	2
Issuance of common stock upon exercise of stock options, shares		320
Issuance of common stock upon vesting of restricted stock units, net of taxes withheld, shares		74,148
Issuance of common stock pursuant to employee stock purchase plans	64		64
Issuance of common stock pursuant to employee stock purchase plans, shares		10,272
Stock-based compensation expense	25,978		25,978
Other comprehensive loss	(1,869)			(1,869)
Net loss	(90,628)				(90,628)
Ending Balance at Jun. 30, 2022	$ 530,931	$ 5	$ 1,277,349		$ (744,554)
Ending balance, shares at Jun. 30, 2022		52,024,621