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Intangible assets (Details) - USD ($)
12 Months Ended
Aug. 28, 2014
Jun. 15, 2009
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Intangible assets          
Accumulated amortization     $ (12,935,000) $ (11,198,000)  
Intangible assets, net     12,543,000 14,616,000  
Write off of capitalized patent filing costs     395,000    
Payment made to acquire asset     59,000 5,000 $ 361,000
Intangible assets, gross     25,478,000 25,814,000  
Amortization expense     1,737,000 1,737,000 1,660,000
Aggregate amortization of intangible assets for each of the next five years and thereafter          
2020     1,737,000    
2021     1,737,000    
2022     1,737,000    
2023     1,642,000    
2024     1,333,000    
Thereafter     3,871,000    
Finite lived intangible assets, net     12,057,000    
Proprietary modified-release drug delivery technology          
Intangible assets          
Amount of finite-lived intangibles   $ 15,600,000      
Intangible assets - Useful life   20 years      
Intangible assets, gross     15,600,000 15,600,000  
Tussionex ANDA          
Intangible assets          
Payment made to acquire asset $ 4,200,000        
Legal fees 90,000        
Earnout fair value 589,000        
Intangible assets, gross     4,829,000 4,829,000  
Tussionex ANDA | Other income (expense)          
Intangible assets          
Increase (decrease) in fair value of earnout liability     (7,000) (133,000) $ (62,000)
CPI Profit Sharing          
Intangible assets          
Payment made to acquire asset 2,000,000        
Legal fees $ 43,000        
Intangible assets, gross     2,043,000 2,043,000  
Patents          
Intangible assets          
Intangible assets, gross     1,971,000 2,307,000  
Other          
Intangible assets          
Intangible assets, gross     $ 1,035,000 $ 1,035,000  
Tussionex ANDA and CPI profit sharing          
Intangible assets          
Intangible assets - Useful life 10 years