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Property and equipment (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Property and equipment      
Property and equipment gross $ 17,832 $ 16,840  
Accumulated depreciation and amortization (including $1,153 and $633 at December 31, 2019 and 2018 respectively, applicable to finance leases) (10,487) (8,926)  
Property and equipment, net 7,345 7,914  
Depreciation and amortization of property and equipment 2,059 1,750 $ 1,363
Finance lease accumulated depreciation and amortization 1,153 633  
Assets under finance lease      
Property and equipment      
Property and equipment gross 3,733 3,327  
Leasehold improvements      
Property and equipment      
Property and equipment gross 4,392 4,340  
Manufacturing, packaging and lab equipment      
Property and equipment      
Property and equipment gross 7,088 6,821  
Office furniture and equipment      
Property and equipment      
Property and equipment gross 1,888 2,164  
Assets under construction      
Property and equipment      
Property and equipment gross $ 731 $ 188