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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Cash Flows From Operating Activities:      
Net loss $ (83,333,000) $ (30,781,000) $ (20,849,000)
Adjustments to reconcile net loss to net cash used in operating activities:      
Share-based compensation expense 3,460,000 1,181,000 210,000
Depreciation and amortization of property and equipment 1,598,000 1,724,000 1,645,000
Amortization of intangible assets 1,593,000 1,495,000 1,037,000
Changes in fair value of warrant and earnout liabilities 18,000 1,313,000 249,000
Amortization of patents 69,000 23,000 31,000
Amortization of senior debt fees 406,000 576,000 182,000
Amortization of short-term investment purchase discounts (156,000)    
Deferred interest on debt 4,738,000 548,000 511,000
Loss on debt extinguishment 942,000   445,000
Gain on sale of equipment (922,000) (831,000) (824,000)
Change in deferred rent 8,000 (23,000) 41,000
Realized gain on sale of short-term investments (3,000)    
Provision for bad debts     (264,000)
Changes in operating assets and liabilities:      
Accounts receivable (2,232,000) (3,536,000) 417,000
Inventories (3,247,000) (489,000) (1,612,000)
Deferred contract sales organization fees (720,000)    
Other current assets (1,807,000) (794,000) (167,000)
Other assets 183,000 (266,000) (231,000)
Accounts payable 2,974,000 3,567,000 284,000
Accrued expenses 2,123,000 426,000 1,505,000
Deferred revenue 3,662,000    
Net cash used in operating activities (70,646,000) (25,867,000) (17,390,000)
Cash Flows From Investing Activities:      
Purchases of short-term investments (66,088,000)    
Sales and maturities of short-term investments 50,816,000 3,000,000 4,497,000
Capital expenditures (3,550,000) (1,023,000) (339,000)
Intangible asset acquisition (500,000)   (6,283,000)
Net cash provided by (used in) investing activities (19,322,000) 1,977,000 (2,125,000)
Cash Flows From Financing Activities:      
Proceeds from Deerfield debt note, net of fees 58,419,000    
Proceeds from senior debt note   10,000,000 15,000,000
Prepayment of senior debt and fee (26,063,000)    
Proceeds from sale of equipment 415,000   795,000
Net proceeds from issuance of stock 13,000 18,122,000 17,350,000
Net proceeds from initial public offering, net of underwriting discounts, commissions and offering costs   75,013,000  
Payments made on borrowings (9,166,000) (1,654,000) (11,671,000)
Payments made to purchase treasury stock (61,000) (171,000)  
Deferred financing costs     (563,000)
Net cash provided by financing activities 23,557,000 101,310,000 20,911,000
Increase (decrease) in cash and cash equivalents (66,411,000) 77,420,000 1,396,000
Cash and Cash Equivalents:      
Beginning 90,763,000 13,343,000 11,947,000
Ending 24,352,000 90,763,000 13,343,000
Noncash Investing and Financing Activities:      
Earnout liability incurred in connection with intangible assets acquisition     589,000
Issuance of stock warrants   2,131,000 1,707,000
Exercise of Series C warrants for Series C Preferred Stock   2,322,000  
Cashless exercise of Series C warrants from Series C financing in IPO closing   2,842,000  
Conversion of Redeemable Preferred Stocks into Common Stock   110,776,000  
Reclassification of Series C warrants issued with senior debt upon IPO closing   611,000  
Preferred stock accretion   1,169,000 1,118,000
Preferred stock dividend   1,221,000 2,185,000
Supplemental Cash Flow Information:      
Interest paid $ 2,857,000 $ 2,524,000 $ 1,793,000