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Stock Option Plan - Schedule of Share-based Compensation Expenses (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]      
Total share-based compensation expense $ 1,573 $ 2,384 $ 177
Research and development      
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]      
Total share-based compensation expense 477 541 98
General and administrative      
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]      
Total share-based compensation expense $ 1,096 1,433 $ 79
Discontinued operations      
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]      
Total share-based compensation expense   $ 410