Condensed Consolidated Statements of Stockholders' Equity (unaudited) - USD ($) $ in Thousands	Total	Common Stock Purchase Agreement	Public offering	Common Warrant	Pre Funded Warrant June 2022 Registered Direct Offering	Common Stock	Common Stock Common Stock Purchase Agreement	Common Stock Public offering	Common Stock Common Warrant	Common Stock Pre Funded Warrant June 2022 Registered Direct Offering	Additional Paid-In Capital	Additional Paid-In Capital Common Stock Purchase Agreement	Additional Paid-In Capital Public offering	Additional Paid-In Capital Common Warrant	Additional Paid-In Capital Pre Funded Warrant June 2022 Registered Direct Offering	Treasury Stock	Accumulated Deficit
Beginning balance at Dec. 31, 2020	$ 2,977					$ 1					$ 252,408					$ (155)	$ (249,277)
Beginning balance, in shares (in shares) at Dec. 31, 2020						14,570,009
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	36										36
Exercise of common stock warrants				$ 442										$ 442
Exercise of common stock warrants (in shares)									99,651
Common stock issued pursuant to common stock purchase agreement		$ 6,334					$ 1					$ 6,333
Common stock issued pursuant to common stock purchase agreement (in shares)							493,163
Exercise of stock options	13										13
Exercise of stock options (in shares)						2,492
Net loss	(8,952)																(8,952)
Ending balance at Mar. 31, 2021	850					$ 2					259,232					(155)	(258,229)
Ending balance, in shares (in shares) at Mar. 31, 2021						15,165,315
Beginning balance at Dec. 31, 2020	2,977					$ 1					252,408					(155)	(249,277)
Beginning balance, in shares (in shares) at Dec. 31, 2020						14,570,009
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(21,459)
Ending balance at Sep. 30, 2021	26,185					$ 2					297,074					(155)	(270,736)
Ending balance, in shares (in shares) at Sep. 30, 2021						18,815,142
Beginning balance at Mar. 31, 2021	850					$ 2					259,232					(155)	(258,229)
Beginning balance, in shares (in shares) at Mar. 31, 2021						15,165,315
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	215										215
Exercise of common stock warrants				$ 19										$ 19
Exercise of common stock warrants (in shares)									3,900
Common stock issued pursuant to common stock purchase agreement			$ 37,236										$ 37,236
Common stock issued pursuant to common stock purchase agreement (in shares)								3,636,364
Exercise of stock options	29										29
Exercise of stock options (in shares)						6,150
Extinguishment of fractional shares resulting from reverse stock split (in shares)						(37)
Net loss	(6,023)																(6,023)
Ending balance at Jun. 30, 2021	32,326					$ 2					296,731					(155)	(264,252)
Ending balance, in shares (in shares) at Jun. 30, 2021						18,811,692
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	327										327
Exercise of stock options	16										16
Exercise of stock options (in shares)						3,450
Net loss	(6,484)																(6,484)
Ending balance at Sep. 30, 2021	26,185					$ 2					297,074					(155)	(270,736)
Ending balance, in shares (in shares) at Sep. 30, 2021						18,815,142
Beginning balance at Dec. 31, 2021	$ 18,319					$ 2					297,441					(155)	(278,969)
Beginning balance, in shares (in shares) at Dec. 31, 2021	18,815,892					18,815,892
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	$ 381										381
Exercise of common stock warrants	562										562
Exercise of common stock warrants (in shares)						164,230
Net loss	(13,380)																(13,380)
Ending balance at Mar. 31, 2022	5,882					$ 2					298,384					(155)	(292,349)
Ending balance, in shares (in shares) at Mar. 31, 2022						18,980,122
Beginning balance at Dec. 31, 2021	$ 18,319					$ 2					297,441					(155)	(278,969)
Beginning balance, in shares (in shares) at Dec. 31, 2021	18,815,892					18,815,892
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	$ (28,288)
Ending balance at Sep. 30, 2022	$ 6,760					$ 2					314,170					(155)	(307,257)
Ending balance, in shares (in shares) at Sep. 30, 2022	24,462,228					24,462,228
Beginning balance at Mar. 31, 2022	$ 5,882					$ 2					298,384					(155)	(292,349)
Beginning balance, in shares (in shares) at Mar. 31, 2022						18,980,122
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	453										453
Exercise of common stock warrants	772				$ 14,020						772				$ 14,020
Exercise of common stock warrants (in shares)						220,795				2,080,696
Net loss	(8,878)																(8,878)
Ending balance at Jun. 30, 2022	12,249					$ 2					313,629					(155)	(301,227)
Ending balance, in shares (in shares) at Jun. 30, 2022						21,281,613
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	509										509
Exercise of common stock warrants					$ 32										$ 32
Exercise of common stock warrants (in shares)										3,180,615
Net loss	(6,030)																(6,030)
Ending balance at Sep. 30, 2022	$ 6,760					$ 2					$ 314,170					$ (155)	$ (307,257)
Ending balance, in shares (in shares) at Sep. 30, 2022	24,462,228					24,462,228