Organization and Significant Accounting Policies - Additional Information (Details)		3 Months Ended		6 Months Ended	9 Months Ended
	May 25, 2021 shares	Sep. 30, 2022 USD ($) shares	Sep. 30, 2021 USD ($)	Jun. 30, 2022 segment	Sep. 30, 2022 USD ($) segment shares	Sep. 30, 2021 USD ($)	Dec. 31, 2021 USD ($) shares
Organization And Significant Accounting Policies [Line Items]
Reverse stock split conversion ratio	0.1
Fractional shares issued, reverse stock split (in shares) | shares	0
Accumulated deficit		$ (307,257,000)			$ (307,257,000)		$ (278,969,000)
Cash and cash equivalents		14,903,000	$ 59,960,000		14,903,000	$ 59,960,000	47,085,000
Prepaid insurance		619,000			619,000		1,697,000
Prepaid expenses and other current assets		3,664,000			3,664,000		2,572,000
Accrued expenses		27,626,000			27,626,000		4,988,000
Other accrued expenses		2,438,000			$ 2,438,000		2,231,000
Number of segments (in segments) | segment				1	2
Promotion, marketing and advertising costs		710,000	0		$ 1,288,000	0
Allowance for credit loss		$ 0			$ 0		$ 0
Common stock, shares outstanding (in shares) | shares	15,170,678	24,462,228			24,462,228		18,815,892
Reclassification adjustment
Organization And Significant Accounting Policies [Line Items]
Accrued expenses							$ 2,164,000
Other accrued expenses							2,164,000
Reclassification adjustment | Reclass Of Prepaid Insurance
Organization And Significant Accounting Policies [Line Items]
Prepaid insurance							1,697,000
Prepaid expenses and other current assets							1,697,000
Reclassification adjustment | Reclass Of Leasing Arrangement Assets
Organization And Significant Accounting Policies [Line Items]
Prepaid expenses and other current assets							109,000
Other current assets related to leasing arrangement							$ 109,000
Board Members
Organization And Significant Accounting Policies [Line Items]
Common stock, shares outstanding (in shares) | shares		124,497			124,497		100,497
License and collaboration revenues
Organization And Significant Accounting Policies [Line Items]
Revenue		$ 492,000	680,000		$ 2,010,000	2,174,000
License and collaboration revenues | Amended Sato Agreement
Organization And Significant Accounting Policies [Line Items]
Revenue		$ 646,000	$ 680,000		$ 1,939,000	$ 2,174,000