Stockholders' Equity (Tables)

9 Months Ended

Sep. 30, 2022

Equity [Abstract]

Schedule of Reserved Shares of Common Stock for Future Issuance

The Company had reserved shares of common stock for future issuance as follows:

	September 30, 2022	December 31, 2021
Outstanding warrants to purchase common stock	5,535,637	1,274,176
Outstanding stock options (Note 16)	1,046,003	518,553
Outstanding stock appreciation rights (Note 16)	60,000	60,000
Nonvested restricted stock units (Note 16)	464,206	—
For possible future issuance under the 2016 Stock Plan (Note 16)	221,568	1,213,224
	7,327,414	3,065,953

The following table presents the Company’s outstanding warrants to purchase common stock and pre-funded warrants for the periods indicated.

	September 30, 2022	December 31, 2021	Exercise Price Per Share
Warrants to purchase common stock issued in the January 2018 Offering	—	999,850	$	46.60
Warrants to purchase common stock issued in the June 2022 Registered Direct Offering	5,261,311	—	2.851
Warrants to purchase common stock issued in the March 2020 Public Offering	252,417	252,417	3.00
Underwriter warrants to purchase common stock associated with the March 2020 Public Offering	11,304	11,304	3.75
Placement agent warrants to purchase common stock issued in the March 2020 Registered Direct Offering	10,605	10,605	5.375
	5,535,637	1,274,176