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Income Taxes - Reconciliation of Federal Income Tax Rate to Losses Before Income Tax Benefit (Detail) - USD ($)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Income Tax Disclosure [Abstract]    
Income tax benefit at federal statutory rate $ (6,379,000) $ (6,140,000)
State income taxes, net of federal benefit (582,000) (570,000)
Non-deductible expenses 193,000 154,000
Federal rate impact 0 0
Research and development tax credits (1,225,000) (1,254,000)
Other 330,000 380,000
Change in valuation allowance 7,663,000 7,430,000
Total income tax provision $ 0 $ 0