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Property and Equipment, Net - Components of Property and Equipment (Details) - USD ($)
$ in Thousands
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Property, Plant and Equipment [Line Items]                
Property and equipment, gross $ 16,185       $ 20,456      
Less: Accumulated depreciation and amortization (5,679)       (4,588)      
Property and equipment, net 10,506 $ 10,569 $ 11,054 $ 11,657 15,868 $ 16,129 $ 16,327 $ 16,474
Computer equipment                
Property, Plant and Equipment [Line Items]                
Property and equipment, gross 575       577      
Furniture and fixtures                
Property, Plant and Equipment [Line Items]                
Property and equipment, gross 305       312      
Laboratory equipment                
Property, Plant and Equipment [Line Items]                
Property and equipment, gross 7,898       7,442      
Office equipment                
Property, Plant and Equipment [Line Items]                
Property and equipment, gross 339       400      
Building related to facility lease obligation                
Property, Plant and Equipment [Line Items]                
Property and equipment, gross 0       10,557      
Leasehold improvements                
Property, Plant and Equipment [Line Items]                
Property and equipment, gross $ 7,068       $ 1,168