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Licensing Arrangements (Details) - Amended Sato Agreement
9 Months Ended
Nov. 07, 2019
JPY (¥)
Nov. 07, 2019
USD ($)
Mar. 14, 2019
JPY (¥)
Mar. 14, 2019
USD ($)
Oct. 23, 2018
JPY (¥)
Oct. 23, 2018
USD ($)
Oct. 05, 2018
USD ($)
Jan. 19, 2017
JPY (¥)
Jan. 19, 2017
USD ($)
Jan. 12, 2017
JPY (¥)
Jan. 12, 2017
USD ($)
Sep. 30, 2019
Sep. 13, 2019
JPY (¥)
Feb. 14, 2019
JPY (¥)
Dec. 31, 2018
JPY (¥)
Dec. 31, 2018
USD ($)
Oct. 05, 2018
JPY (¥)
Jan. 12, 2017
USD ($)
Collaborative Arrangements Transactions [Line Items]                                    
Upfront payment receivable                                 ¥ 1,250,000,000  
Upfront payment installments                         ¥ 500,000,000 ¥ 500,000,000     250,000,000  
Payment received under license agreement     ¥ 500,000,000 $ 4,460,000 ¥ 250,000,000 $ 2,224,000   ¥ 1,250,000,000 $ 10,813,000 ¥ 1,250,000,000 $ 10,813,000              
Aggregate development and regulatory milestone payments potentially receivable under license agreement                   2,750,000,000             1,750,000,000  
Aggregate Phase 1 trial milestone payment term under license agreement                   250,000,000         ¥ 250,000,000 $ 2,162,000   $ 2,162,000
Aggregate becoming payable upon earlier of specified future dates or achievement of milestone events                                 1,000,000,000  
Aggregate commercial milestone payments potentially receivable under license agreement                   ¥ 900,000,000             ¥ 3,900,000,000  
License agreement additional term                       2 years            
Maximum preclinical studies amount | $                     $ 1,000,000              
Written notice to terminate, period                   120 days 120 days              
Written notice to terminate due to material breach, term                   60 days 60 days              
Upfront fee refundable in event of termination | $             $ 0                      
Subsequent Event                                    
Collaborative Arrangements Transactions [Line Items]                                    
Payment received under license agreement ¥ 500,000,000.0 $ 4,554,000