Organization and Significant Accounting Policies - Schedule of Estimated Useful Lives of Property and Equipment (Details)	12 Months Ended
	Dec. 31, 2018
Computer and office equipment
Property, Plant and Equipment [Line Items]
Property and equipment, estimated useful life	3 years
Furniture and fixtures | Minimum
Property, Plant and Equipment [Line Items]
Property and equipment, estimated useful life	5 years
Furniture and fixtures | Maximum
Property, Plant and Equipment [Line Items]
Property and equipment, estimated useful life	7 years
Laboratory equipment
Property, Plant and Equipment [Line Items]
Property and equipment, estimated useful life	7 years
Building asset under facility lease
Property, Plant and Equipment [Line Items]
Property and equipment, estimated useful life	25 years