X0306 4 2020-06-08 0 0001437402 ARDELYX, INC. ARDX 0001466562 Renz Justin A C/O ARDELYX, INC. 34175 ARDENWOOD BLVD FREMONT CA 94555 0 1 0 0 Chief Financial Officer Common Stock 2020-06-08 4 A 0 10000 0 A 13000 D Stock Option (Right to Buy) 7.35 2020-06-08 4 A 0 195017 0.00 A 2030-06-08 Common Stock 195017 195017 D Restricted stock units ("RSUs"). The Reporting Person is entitled to receive one (1) share of Common Stock for each one (1) RSU upon the vesting thereof. Includes 10,000 RSUs. The shares subject to the option vest according to the following schedule: Twenty-five percent (25%) of the shares subject to the option vest on the first anniversary measured from June 8, 2020, and the remaining shares subject to the option vest in 36 successive, equal monthly installments thereafter, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date. /s/ Elizabeth Grammer, Attorney-in-Fact for Justin Renz 2020-06-09