Commitments and Contingencies (Details) $ in Thousands					1 Months Ended	3 Months Ended	6 Months Ended
	Mar. 04, 2022 item	Jun. 16, 2021 USD ($)	Nov. 10, 2019 plaintiff	Jun. 20, 2017 patent	Mar. 31, 2017 shareholder	Jun. 30, 2022 USD ($)	Jun. 30, 2022 USD ($)
Commitments and Contingencies
Purchase commitments						$ 35,100	$ 35,100
Payments on derecognition of lease components		$ 1,100
Number of putative shareholders | shareholder					2
Number of new independent directors agreed to elect | item	1
Litigation expense						$ 2,325
Number of patents in salt and polymorph patent family | patent				2
Number of opponents | plaintiff			1
Number of years regulatory exclusivity in Europe							10 years
Number of years possible additional regulatory exclusivity							1 year