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License Agreements (Details)
$ in Millions
1 Months Ended 6 Months Ended 12 Months Ended 60 Months Ended
Nov. 19, 2013
USD ($)
Sep. 30, 2021
USD ($)
Apr. 30, 2021
USD ($)
Dec. 31, 2020
item
Feb. 29, 2020
item
Sep. 30, 2019
USD ($)
Jun. 30, 2011
USD ($)
Oct. 31, 2008
Jun. 30, 2022
USD ($)
Dec. 31, 2019
USD ($)
Dec. 31, 2020
USD ($)
License Agreements                      
Number of INDs | item       2              
3B Pharmaceuticals                      
License Agreements                      
Percentage of non-royalty consideration payable on sublicense agreements                 34.00%    
License Agreements Licensor Pfizer | Rucaparib | Minimum                      
License Agreements                      
Annual sales target for sales milestone payments                 $ 250.0    
License Agreements Licensor Pfizer | Rucaparib | Maximum                      
License Agreements                      
Maximum potential future development, regulatory milestone payments                 8.0    
Additional maximum payments payable on attaining the sales target                 $ 170.0    
License Agreement Terms | 3B Pharmaceuticals                      
License Agreements                      
Milestone payments   $ 3.3 $ 2.2                
Acquired in-process research and development           $ 9.4          
Number of INDs | item       2              
Number of additional undisclosed targets | item         3            
Research and development expense                   $ 2.1  
Percentage of royalty on net sales                 6.00%    
License Agreement Terms | License Agreements Licensor Pfizer | Rucaparib                      
License Agreements                      
Upfront payment             $ 7.0        
Milestones paid to Pfizer prior to FDA approval             $ 1.4        
Milestone payments                     $ 82.5
License Agreement Terms | Advenchen Laboratories LLC | License Agreements Lucitanib                      
License Agreements                      
Percentage of non-royalty consideration payable on sublicense agreements               25.00%      
Milestone payment obligation $ 65.0