Segment Information (Tables)

6 Months Ended

Jun. 30, 2022

Segment Information

Schedule of information about reportable segments

The following table presents information about our reportable segments for the three months ended June 30, 2022 and 2021 (in thousands):

	Three months ended June 30,
	2022						2021
	US		Ex-US		Total		US		Ex-US		Total
Product revenue	$	22,736	$	9,407	$	32,143	$	27,680	$	9,140	$	36,820
Operating expenses:
Cost of sales - product		4,461		3,411		7,872		5,402		2,892		8,294
Cost of sales - intangible asset amortization		620		723		1,343		620		723		1,343
Research and development		34,409		2,017		36,426		43,774		1,985		45,759
Selling, general and administrative		26,574		6,016		32,590		26,351		6,567		32,918
Acquired in-process research and development		—		—		—		2,204		—		2,204
Other operating expenses		13,293		—		13,293		3,884		—		3,884
Total expenses		79,357		12,167		91,524		82,235		12,167		94,402
Operating loss	$	(56,621)	$	(2,760)		(59,381)	$	(54,555)	$	(3,027)		(57,582)
Other income (expense):
Interest expense						(9,674)						(8,770)
Foreign currency loss						(2,489)						(206)
Other income						171						107
Other income (expense), net						(11,992)						(8,869)
Loss before income taxes						(71,373)						(66,451)
Income tax benefit						41						3
Net loss					$	(71,332)					$	(66,448)

	Six months ended June 30,
	2022						2021
	US		Ex-US		Total		US		Ex-US		Total
Product revenue	$	47,244	$	19,146	$	66,390	$	59,381	$	15,492	$	74,873
Operating expenses:
Cost of sales - product		9,295		6,647		15,942		11,560		5,002		16,562
Cost of sales - intangible asset amortization		1,241		1,445		2,686		1,241		1,445		2,686
Research and development		74,874		3,802		78,676		94,604		3,960		98,564
Selling, general and administrative		50,493		11,310		61,803		50,672		12,187		62,859
Acquired in-process research and development		—		—		—		2,204		—		2,204
Other operating expenses		17,023		—		17,023		7,591		—		7,591
Total expenses		152,926		23,204		176,130		167,872		22,594		190,466
Operating loss	$	(105,682)	$	(4,058)		(109,740)	$	(108,491)	$	(7,102)		(115,593)
Other income (expense):
Interest expense						(18,774)						(16,807)
Foreign currency loss						(3,468)						(752)
Other income						320						290
Other income (expense), net						(21,922)						(17,269)
Loss before income taxes						(131,662)						(132,862)
Income tax benefit						162						137
Net loss					$	(131,500)					$	(132,725)