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Share-Based Compensation (Details) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 6 Months Ended 38 Months Ended
Jun. 30, 2012
Jun. 30, 2011
Jun. 30, 2012
Jun. 30, 2011
Jun. 30, 2012
Share-based compensation expense recognized in the accompanying Consolidated Statements of Operations and Comprehensive Loss          
Share-based compensation expense $ 1,168 $ 338 $ 2,114 $ 397 $ 3,511
Research and development [Member]
         
Share-based compensation expense recognized in the accompanying Consolidated Statements of Operations and Comprehensive Loss          
Share-based compensation expense 592 172 1,032 206 1,693
General and administrative [Member]
         
Share-based compensation expense recognized in the accompanying Consolidated Statements of Operations and Comprehensive Loss          
Share-based compensation expense $ 576 $ 166 $ 1,082 $ 191 $ 1,818