X0306 4 2022-03-01 0 0001466301 Clovis Oncology, Inc. CLVS 0001266569 MAHAFFY PATRICK J C/O CLOVIS ONCOLOGY, INC. 5500 FLATIRON PARKWAY, SUITE 100 BOULDER CO 80301 1 1 0 0 See Remarks Stock Option (right to buy) 1.95 2022-03-01 4 A 0 220000 0.00 A 2032-03-01 Common Stock 220000 220000 D Stock Option (right to buy) 1.95 2022-03-01 4 A 0 80000 0.00 A 2032-03-01 Common Stock 80000 80000 D Stock Option (right to buy) 1.95 2022-03-01 4 A 0 80000 0.00 A 2032-03-01 Common Stock 80000 80000 D The option shall vest as to 25% of the shares on March 1, 2023, and the remainder shall vest in substantially equal installments over the 36 months immediately following such date. The option shall vest in the event Product Revenues for the Company's fiscal year ending December 31, 2022 meet or exceed its corresponding budgeted amount in the Company's budget as approved by the Board on December 2, 2021. The option shall vest on December 31, 2022 if as of such date the Company has sufficient cash and cash equivalents or available sources of borrowings to fund the Company's operating plan, as approved by the Board as of such date, into 2024. President and Chief Executive Officer /s/ Patrick Mahaffy 2022-03-02