X0306 4 2019-02-01 0 0001466301 Clovis Oncology, Inc. CLVS 0001266569 MAHAFFY PATRICK J C/O CLOVIS ONCOLOGY, INC. 5500 FLATIRON PARKWAY, SUITE 100 BOULDER CO 80301 1 1 0 0 See Remarks Stock Option (right to buy) 25.75 2019-02-01 4 A 0 200000 0.00 A 2029-02-01 Common Stock 200000 200000 D Stock Option (right to buy) 25.75 2019-02-01 4 A 0 100000 0.00 A 2029-02-01 Common Stock 100000 100000 D The option shall vest as to 25% of the shares on February 1, 2020, and the remainder shall vest in substantially equal installments over the 36 months immediately following such date. The option shall vest in the event the Company's Product Revenues for the Company's fiscal year ending December 31, 2019 meet or exceed its corresponding budgeted amount in the Company's budget as approved by the Board of Directors on December 6, 2018. President and Chief Executive Officer /s/ Patrick Mahaffy 2019-02-01