X0306 4 2022-03-22 0 0001808865 iTeos Therapeutics, Inc. ITOS 0001465914 Davis Aaron I. 12860 EL CAMINO REAL, SUITE 300 SAN DIEGO CA 92130 1 0 0 0 Common Stock 2022-03-22 4 P 0 21300 31.875 A 3163358 I See footnote Common Stock 2022-03-22 4 P 0 3700 33.0898 A 3167058 I See footnote Common Stock 2022-03-22 4 P 0 5000 33.4278 A 3172058 I See footnote Common Stock 2022-03-23 4 P 0 20000 32.849 A 3192058 I See footnote These securities are owned directly by Boxer Capital, LLC ("Boxer Capital"). The reporting person may be deemed to be a member of a "group" for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended, consisting of (i) Boxer Capital, (ii) Boxer Asset Management Inc., (iii) the reporting person, and (iv) Joe Lewis. The reporting person disclaims beneficial ownership of these securities to the extent he does not have a pecuniary interest therein. /s/ Aaron I. Davis 2022-03-24