X0206 3 2021-09-14 0 0001863127 Tyra Biosciences, Inc. TYRA 0001465837 Boxer Capital, LLC 12860 EL CAMINO REAL, SUITE 300 SAN DIEGO CA 92130 0 0 1 0 0001465836 Boxer Asset Management Inc. C/O CAY HOUSE P.O. BOX N-7776 E.P. TAYLOR DRIVE LYFORD CAY NEW PROVIDENCE C5 N7776 BAHAMAS 0 0 1 0 0001015747 LEWIS JOSEPH C/O CAY HOUSE P.O. BOX N-7776 E.P. TAYLOR DRIVE LYFORD CAY NEW PROVIDENCE C5 BAHAMAS 0 0 1 0 0001468223 MVA Investors, LLC 11682 EL CAMINO REAL, SUITE 300 SAN DIEGO CA 92130 0 0 1 0 0001465914 Davis Aaron I. 12860 EL CAMINO REAL, SUITE 300 SAN DIEGO CA 92130 0 0 1 0 Series A Preferred Stock 0.00 Common Stock 3844780 D Series A Preferred Stock 0.00 Common Stock 248093 D Series B Preferred Stock 0.00 Common Stock 1853579 D Series B Preferred Stock 0.00 Common Stock 40002 D The shares of Series A Preferred Stock and Series B Preferred Stock are convertible, at any time, at the holder's election, to shares of the Issuer's common stock at a ratio of 1-for-2.5974. In addition, effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of Series A Preferred Stock and Series B Preferred Stock will automatically convert to shares of the Issuer's common stock at a ratio of 1-for-2.9574. The Series A Preferred Stock and Series B Preferred Stock has no expiration date. These securities are held directly by Boxer Capital, LLC ("Boxer Capital"), which may be deemed to be a member of a "group" for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended, consisting of (i) Boxer Capital, (ii) Boxer Asset Management Inc. ("Boxer Management"), (iii) Joseph C. Lewis, (iv) MVA Investors, LLC and (v) Aaron I. Davis (collectively, the "Boxer Group"), and indirectly by Boxer Management and Joseph C. Lewis by virtue of their ownership in Boxer Capital. Each member of the Boxer Group other than Boxer Capital disclaims beneficial ownership of these securities to the extent it or he does not have a pecuniary interest therein. These securities are held directly by MVA Investors, which may be deemed to be a member of the Boxer Group for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended, and indirectly by Mr. Davis who is a member of and has voting and dispositive power over securities held by MVA Investors. Each member of the Boxer Group other than MVA Investors disclaims beneficial ownership of these securities to the extent it or he does not have a pecuniary interest therein. Boxer Capital, LLC, By: /s/ Aaron I. Davis, Aaron I. Davis, Chief Executive Officer 2021-09-14 Boxer Asset Management Inc., By: /s/ Jason C. Callender, Jason C. Callender, Director 2021-09-14 /s/ Joseph C. Lewis 2021-09-14 MVA Investors, LLC, By: /s/ Aaron I. Davis, Aaron I. Davis, Chief Executive Officer 2021-09-14 /s/ Aaron I. Davis 2021-09-14