X0306 4 2017-10-03 0 0001576263 Mirati Therapeutics, Inc. MRTX 0001465837 Boxer Capital, LLC 11682 EL CAMINO REAL, SUITE 320 SAN DIEGO CA 92130 0 0 1 0 0001465836 Boxer Asset Management Inc. C/O CAY HOUSE P.O. BOX N-7776 E.P. TAYLOR DRIVE LYFORD CAY NEW PROVIDENCE C5 BAHAMAS 0 0 1 0 Common Stock 2017-10-03 4 X 0 189780 7.86 A 1227774 D Common Stock 2017-10-03 4 X 0 78186 7.86 A 513630 D Warrant (right to purchase) 7.86 2017-10-03 4 X 0 189780 0.00 D 2012-11-21 2017-11-21 Common Stock 189780 0 D Warrant (right to purchase) 7.86 2017-10-03 4 X 0 78186 0.00 D 2012-11-21 2017-11-21 Common Stock 78186 0 D These securities are owned directly by Boxer Capital, LLC ("Boxer Capital"), which may be deemed to be a member of a "group" for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended, consisting of (i) Boxer Capital, (ii) Boxer Asset Management Inc., (iii) MVA Investors, LLC ("MVA Investors"), (iv) Braslyn Ltd., (v) Joe Lewis, (vi) Christopher Fuglesang, (vii) Rodney W. Lappe, (viii) Ivan M. Lieberburg, (ix) Neil Reisman, (x) Shehan B. Dissanayake, and (xi) Aaron I. Davis (collectively, the "Boxer Group"). Joseph C. Lewis is the sole indirect beneficial owner of and controls Braslyn Ltd. These securities are owned directly and solely by MVA Investors, which has sole voting and dispositive power with respect to these securities. Each of Messrs. Fuglesang, Lieberburg, Reisman, Dissanayake and Davis is a member of MVA Investors. Each member of the Boxer Group other than MVA Investors disclaims beneficial ownership of these securities to the extent it or he does not have a pecuniary interest therein. Form 2 of 2. Because the number of Reporting Persons exceeds the Form 4 limit, additional Reporting Persons are included on another Form 4 filed on the same date. Boxer Capital, LLC, By: /s/ Aaron I Davis, Aaron I. Davis 2017-10-03 Boxer Asset Management, Inc., By: /s/ Jason Callender, Jason Callender 2017-10-03