X0609 4 2026-11-06 0001464521 Heartflow, Inc. HTFL 0001900415 Farquhar John C.M. false C/O HEARTFLOW, INC. 135 MAIN STREET, SUITE 1000 SAN FRANCISCO CA 94105 1 1 Chief Executive Officer 1 Common Stock 2026-11-06 4 F 0 7751 52.40 D 275263 D Common Stock 2026-11-10 4 M 0 15620 2.22 A 290883 D Common Stock 2026-11-10 4 S 0 38900 55.74 D 251983 D Stock Option 2.22 2026-11-10 4 M 0 15620 0 D 2033-07-10 Common Stock 15620 1969017 D Represents shares that have been retained by the Issuer to satisfy income tax withholding and remittance obligations in connection with the vesting and net settlement of restricted stock units previously reported. The transaction reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2025. Includes the sale of 23,280 shares of common stock held and the option exercise and sale of 15,620 shares reported on this Form 4 that were effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on September 12, 2025. The option vests and becomes exercisable in monthly installments until July 1, 2027, subject to continued service through the applicable vesting date. /s/ Nga Van, by power of attorney 2026-11-10