X0609 4 2026-09-02 0001464521 Heartflow, Inc. HTFL 0002079946 Verghese Vikram false C/O HEARTFLOW, INC. 135 MAIN STREET, SUITE 1000 SAN FRANCISCO CA 94105 1 Chief Financial Officer 1 Common Stock. 2026-09-02 4 S 0 5876 50.60 D 248683 D Common Stock. 2026-09-03 4 S 0 27540 49.6903 D 221143 D The transaction reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 4, 2026. This transaction was executed in multiple trades at price ranging from $48.22 to $50.80. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ Nga Van, by power of attorney 2026-09-04