Summary of Significant Accounting Policies - Going Concern (Details) - USD ($)		3 Months Ended												12 Months Ended					24 Months Ended
	Jan. 17, 2024	Dec. 31, 2023	Sep. 30, 2023	Jun. 30, 2023	Mar. 31, 2023	Dec. 31, 2022	Sep. 30, 2022	Jun. 30, 2022	Mar. 31, 2022	Dec. 31, 2021	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021	Apr. 30, 2025	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2023
Net Loss		$ (19,880,000)	$ (10,983,000)	$ (9,045,000)	$ (10,241,000)	$ (10,759,000)	$ (9,477,000)	$ (10,022,000)	$ (10,506,000)	$ (11,493,000)	$ (10,488,000)	$ (9,245,000)	$ (9,151,000)			$ (50,149,077)	$ (40,763,573)	$ (40,377,160)
Net Cash Flows Used in Operating Activities																(26,277,824)	(24,521,082)	(26,980,411)
Accumulated Deficit		$ 293,984,793				$ 243,835,716										293,984,793	243,835,716		$ 293,984,793
Net Cash Flows Used in Investing Activities																$ (19,280,966)	$ (21,170,816)	$ (4,852,452)
Minimum
Rate of issuance of stock awards or stock options due to salary reduction program														150.00%
Maximum
Rate of issuance of stock awards or stock options due to salary reduction program														200.00%
Atomistic agreement | Atomistic SAS
Payments for investment to Atomistic																			$ 32,500,000
Subsequent Event
Decrease in cash annual operating expenses	$ 8,000,000
Percentage of decrease in cash annual operating expenses	20.00%
Forecast [Member]
Expected cash saving due to payroll reduction program														$ 1,200,000
Estimated total common stock value to be issued and sold															$ 50,000,000
Forecast [Member] | Minimum
Percentage of optional salary reductions														10.00%
Forecast [Member] | Maximum
Percentage of optional salary reductions														30.00%
Forecast [Member] | Atomistic agreement | Atomistic SAS
Payments for investment to Atomistic															$ 5,000,000
License term															25 years