CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($)	Preferred Stock	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Total
Balance at Dec. 31, 2018	$ 50	$ 27,591	$ 148,695,775	$ (118,266,441)	$ 30,456,975
Balance (in shares) at Dec. 31, 2018	49,626	27,591,670
Stock-Based Compensation Expense		$ 58	1,404,773		1,404,831
Stock-Based Compensation Expense (in shares)		57,496
Proceeds from Common Stock Offerings		$ 5,479	19,994,528		20,000,007
Proceeds from Common Stock Offerings (in shares)		5,479,454
Direct Costs of Common Stock Offerings			(1,145,000)		(1,145,000)
Net Loss				(26,476,370)	(26,476,370)
Balance at Dec. 31, 2019	$ 50	$ 33,128	168,950,076	(144,742,811)	24,240,443
Balance (in shares) at Dec. 31, 2019	49,626	33,128,620
Stock-Based Compensation Expense		$ 943	2,656,888		2,657,831
Stock-Based Compensation Expense (in shares)		942,986
Stock Option Exercises		$ 44	29,176		29,220
Stock Option Exercises (in shares)		43,854
Stock Warrant Exercises		$ 2,883	14,125,644		14,128,527
Stock Warrant Exercises (in shares)		2,882,647
Proceeds from Common Stock Offerings		$ 8,647	26,741,355		26,750,002
Proceeds from Common Stock Offerings (in shares)		8,647,059
Direct Costs of Common Stock Offerings			(1,550,666)		(1,550,666)
Net Loss				(17,952,172)	(17,952,172)
Balance at Dec. 31, 2020	$ 50	$ 45,645	210,952,473	(162,694,983)	48,303,185
Balance (in shares) at Dec. 31, 2020	49,626	45,645,166
Stock-Based Compensation Expense		$ 368	18,429,556		18,429,924
Stock-Based Compensation Expense (in shares)		368,047
Stock Option Exercises		$ 659	781,618		782,277
Stock Option Exercises (in shares)		659,398
Stock Warrant Exercises		$ 7,277	34,708,451		34,715,728
Stock Warrant Exercises (in shares)		7,276,928
Proceeds from Common Stock Offerings		$ 4,768	97,745,239		97,750,007
Proceeds from Common Stock Offerings (in shares)		4,768,293
Direct Costs of Common Stock Offerings			(6,136,420)		(6,136,420)
Shares Redeemed to Cover Employee Tax Withholdings		$ (83)	(1,144,282)		(1,144,365)
Shares Redeemed to Cover Employee Tax Withholdings (in shares)		(83,164)
Stock Issued for Technology License Purchase		$ 75	1,404,675		1,404,750
Stock Issued for Technology License Purchase (in shares)		75,000
Preferred Stock Converted	$ (50)	$ 4,963	(10,004,913)		(10,000,000)
Preferred Stock Converted (in shares)	(49,626)	4,962,600
Net Loss				(40,377,160)	(40,377,160)
Balance at Dec. 31, 2021		$ 63,672	$ 346,736,397	$ (203,072,143)	$ 143,727,926
Balance (in shares) at Dec. 31, 2021		63,672,268