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Organization - Additional Information (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Organization Consolidation And Presentation Of Financial Statements [Abstract]      
Accumulated deficit $ 400,024 $ 339,299  
Net loss 60,725 93,844 $ 82,177
Cash used in operations 45,060 $ 78,333 $ 72,421
Cash, cash equivalents and marketable securities $ 90,100