X0206 3 2020-12-10 0 0001463361 Unity Biotechnology, Inc. UBX 0001742084 O'Neill Gilmore Neil C/O UNITY BIOTECHNOLOGY, INC. 285 EAST GRAND AVENUE SOUTH SAN FRANCISCO 94080 1 0 0 0 Stock Option (Right to Buy) 9.14 2030-06-17 Common Stock 30000 D Stock Option (Right to Buy) 3.02 2030-09-09 Common Stock 10000 D Shares subject to the stock option vest and become exercisable in successive, equal monthly installments over a 36-month period commencing on June 1, 2020 (the "Vesting Commencement Date"), so that 100% of the shares become fully vested and exercisable on the third anniversary of the Vesting Commencement Date, subject to Reporting Person's continued service relationship with the Issuer on each such vesting date. Shares subject to the stock option vest and become exercisable in successive, equal monthly installments over a 12-month period commencing on September 10, 2020 (the "Vesting Commencement Date"), so that 100% of the shares become fully vested and exercisable on the first anniversary of the Vesting Commencement Date, subject to Reporting Person's continued service relationship with the Issuer on each such vesting date. /s/ Anirvan Ghosh, as Attorney-in-Fact for Gilmore O'Neill 2020-12-14