X0206 3 2019-08-01 1 0001492426 Horizon Therapeutics Public Ltd Co HZNP 0001463321 Mahony Susan C/O HORIZON THERAPEUTICS PLC CONNAUGHT HOUSE, 1ST FL, 1 BURLINGTON RD DUBLIN L2 4 IRELAND 1 0 0 0 /s/ Miles W. McHugh, Attorney-in-Fact 2019-08-05