X0306 4 2018-09-21 0 0001461993 MELINTA THERAPEUTICS, INC. /NEW/ MLNT 0001531049 Milligan Peter J C/O MELINTA THERAPEUTICS, INC. 300 GEORGE STREET, SUITE 301 NEW HAVEN CT 06511 0 1 0 0 Chief Financial Officer Stock Option (right to buy) 4.50 2018-09-21 4 A 0 370000 0.00 A 2028-09-21 Common Stock 370000 370000 D One-quarter of the options will vest and become exercisable on September 17, 2019 and the remainder will vest and become exercisable in substantially equal monthly installments during the three year period commencing on September 17, 2019, subject to Mr. Milligan's continued service with the Company through the applicable vesting date. /s/ Peter Milligan 2018-09-24