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RESEARCH AND LICENSE AGREEMENTS (Details Narrative) - USD ($)
1 Months Ended 3 Months Ended 47 Months Ended
Dec. 31, 2022
Jan. 31, 2022
Jul. 31, 2020
Mar. 31, 2019
Mar. 31, 2024
Mar. 31, 2023
Apr. 30, 2022
Research and development expense         $ 364,385 $ 1,281,817  
Proceeds from convertible debt $ 3,000,000.0            
License Agreement [Member]              
Reimbursement of patent   $ 160,000          
License cost         2,000 5,000  
Sponsored Research and License Agreement [Member]              
License cost         1,000 21,000  
Research and development expense         0 0  
Sponsored Research and License Agreement [Member] | University of Louisville Research Foundation [Member]              
Reimbursement of research expenses       $ 693,000 2,900,000    
Agreement term payment, description     In July 2020, the Company entered into an exclusive license agreement with ULRF for RAS interaction inhibitor drug candidates. Under the agreement, the Company took over development, regulatory approval and commercialization of the candidates from ULRF and is responsible for maintenance of the related intellectual property portfolio. In return, ULRF received approximately $112,000 for an upfront license fee and reimbursement of prior patent costs. In addition, the Company has agreed to pay ULRF (i) royalties, on patent-covered net sales associated with the commercialization, of 4% (on net sales up to a cumulative $250,000,000) or 5% (on net sales above a cumulative $250,000,000), until expiration of the licensed patent, and 2.5% (on net sales for any sales not covered by Licensed Patents), (ii) 30% to 50% of any non-royalty sublicensee income received (50% for sublicenses granted in the first two years of the ULRF license agreement, 40% for sublicenses granted in the third or fourth years of the ULRF license agreement, and 30% for sublicenses granted in the fifth year of the ULRF license agreement or thereafter), (iii) reimbursements for ongoing costs associated with the preparation, filing, prosecution and maintenance of licensed patents, incurred prior to July 2020, and (iv) payments ranging from $50,000 to $5,000,000 upon the achievement of certain regulatory and commercial milestones.        
Marketing approval expenses     $ 300,000        
Revenue     500,000,000       $ 500,000,000
Sponsored Research and License Agreement [Member] | University of Louisville Research Foundation [Member] | Minimum [Member]              
Upfront license fee     20,000        
Sponsored Research and License Agreement [Member] | University of Louisville Research Foundation [Member] | Maximum [Member]              
Upfront license fee     100,000        
License and Sponsored Research Agreements [Member] | University of Louisville Research Foundation [Member]              
Reimbursement of research expenses             $ 805,000
Agreement term payment, description             In addition, the Company agreed to pay ULRF (i) royalties, on patent-covered net sales associated with the commercialization of anti-nucleolin agent-conjugated nanoparticles, of 4% (on net sales up to a cumulative $250,000,000) or 5% (on net sales above a cumulative $250,000,000), until expiration of the last to expire of the licensed patents, (ii) 30% to 50% of any non-royalty sublicensee income received (50% for sublicenses granted in the first two years of the ULRF license agreement, 40% for sublicenses granted in the third or fourth years of the ULRF license agreement, and 30% for sublicenses granted in the fifth year of the ULRF license agreement or thereafter), (iii) reimbursements for ongoing costs associated with the preparation, filing, prosecution and maintenance of licensed patents, incurred prior to June 2018, and (iv) payments ranging from $100,000 to $5,000,000 upon the achievement of certain regulatory and commercial milestones.
Marketing approval expenses             $ 500,000
Proceeds from convertible debt             50,000
Patent costs             200,000
License and Sponsored Research Agreements [Member] | University of Louisville Research Foundation [Member] | Licensed Product Sales [Member]              
Cumulative sales     5,000,000       5,000,000
Regulatory marketing approval, expenses             500,000
License and Sponsored Research Agreements [Member] | University of Louisville Research Foundation [Member] | Minimum [Member]              
Milestone payment     50,000       100,000
Shortfall payments             10,000
License and Sponsored Research Agreements [Member] | University of Louisville Research Foundation [Member] | Maximum [Member]              
Milestone payment     5,000,000       5,000,000
Shortfall payments             50,000
Sponsored Research Agreements And License [Member]              
License cost         25,000 14,000  
Research and development expense         $ 0 $ 223,000  
Upfront Payment [Member] | License Agreement [Member]              
Reimbursement of patent   $ 150,000          
Phase 1 Clinical Trial [Member] | License and Sponsored Research Agreements [Member] | University of Louisville Research Foundation [Member]              
Milestone payment     50,000       100,000
Phase 2 Clinical Trial [Member] | License and Sponsored Research Agreements [Member] | University of Louisville Research Foundation [Member]              
Milestone payment     100,000       200,000
Phase 3 Clinical Trial [Member] | License and Sponsored Research Agreements [Member] | University of Louisville Research Foundation [Member]              
Milestone payment     $ 150,000       $ 350,000