0001493152-19-017100.txt : 20191114 0001493152-19-017100.hdr.sgml : 20191114 20191113215826 ACCESSION NUMBER: 0001493152-19-017100 CONFORMED SUBMISSION TYPE: 10-Q PUBLIC DOCUMENT COUNT: 51 CONFORMED PERIOD OF REPORT: 20190930 FILED AS OF DATE: 20191114 DATE AS OF CHANGE: 20191113 FILER: COMPANY DATA: COMPANY CONFORMED NAME: RITTER PHARMACEUTICALS INC CENTRAL INDEX KEY: 0001460702 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 263474527 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 10-Q SEC ACT: 1934 Act SEC FILE NUMBER: 001-37428 FILM NUMBER: 191216102 BUSINESS ADDRESS: STREET 1: 1880 CENTURY PARK EAST, SUITE 1000 CITY: LOS ANGELES STATE: CA ZIP: 90067 BUSINESS PHONE: 310-203-1000 MAIL ADDRESS: STREET 1: 1880 CENTURY PARK EAST, SUITE 1000 CITY: LOS ANGELES STATE: CA ZIP: 90067 10-Q 1 form10-q.htm

 

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

FORM 10-Q

 

[X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

 

For the Quarterly Period Ended September 30, 2019

 

OR

 

[  ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

 

For the Transition Period from _____________ to _____________

 

Commission File Number: 001-37428

 

RITTER PHARMACEUTICALS, INC.

(Exact name of Registrant as specified in its Charter)

 

Delaware   26-3474527

(State or other jurisdiction of

incorporation or organization)

 

(I.R.S. Employer

Identification Number)

 

1880 Century Park East, Suite 1000

Los Angeles, CA 90067

(Address and zip code of principal executive offices)

 

Registrant’s Telephone Number, Including Area Code: (310) 203-1000

 

Securities Registered Pursuant to Section 12(b) of the Exchange Act:

 

Title of Each Class   Trading Symbol  

Name of Each Exchange on Which Registered

Common Stock, par value $0.001   RTTR   Nasdaq Capital Market

 

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes [X] No [  ]

 

Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes [X] No [  ]

 

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act. (Check one):

 

Large Accelerated Filer [  ] Accelerated Filer [  ]
       
Non-Accelerated Filer [  ] Smaller Reporting Company [X]
(Do not check if a smaller reporting company)      
    Emerging Growth Company [X]

 

If an emerging growth company, indicate by check mark if the Registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. [  ]

 

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes [  ] No [X]

 

As of November 7, 2019, there were 10,164,756 shares of the registrant’s common stock, par value $0.001 per share, outstanding.

 

 

 

 

 

 

TABLE OF CONTENTS

 

    Page
PART I. Financial Information 1
     
Item 1. Condensed Financial Statements 1
  Condensed Balance Sheets as of September 30, 2019 (unaudited) and December 31, 2018 1
  Condensed Statements of Operations and Comprehensive Loss for the Three and Nine Months Ended September 30, 2019 and 2018 (unaudited) 2
  Condensed Statements of Changes in Stockholders’ Equity for the Nine Months ended September 30, 2019 and 2018 (Unaudited) 3
  Condensed Statements of Cash Flows for the Nine Months Ended September 30, 2019 and 2018 (unaudited) 4
  Notes to Unaudited Condensed Financial Statements 5
     
Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations 16
Item 3. Quantitative and Qualitative Disclosures About Market Risk 25
Item 4. Controls and Procedures 26
     
PART II. Other Information 26
     
Item 1. Legal Proceedings 26
Item 1A. Risk Factors 26
Item 2. Unregistered Sales of Equity Securities and Use of Proceeds 27
Item 5. Other Information 27
Item 6. Exhibits 28

 

 

 

 

PART I - FINANCIAL INFORMATION

 

ITEM 1. CONDENSED FINANCIAL STATEMENTS

 

RITTER PHARMACEUTICALS, INC.

CONDENSED BALANCE SHEETS

 

   September 30, 2019   December 31, 2018 
    (unaudited)      
ASSETS          
Current assets          
Cash and cash equivalents  $1,957,395   $7,812,259 
Accrued interest receivable   1,469    54,456 
Investments in marketable securities       6,988,780 
Prepaid expenses   771,199    421,522 
Total current assets   2,730,063    15,277,017 
Other assets          
Right-of-use assets   119,978     
Other assets   32,725    22,725 
Total other assets   152,703    22,725 
Property and equipment, net   17,199    20,160 
Total Assets  $2,899,965   $15,319,902 
           
LIABILITIES AND STOCKHOLDERS’ EQUITY          
Current liabilities          
Accounts payable  $2,566,485   $4,512,316 
Accrued expenses   141,222    1,407,843 
Lease liabilities   119,074     
Other liabilities       13,359 
Total current liabilities   2,826,781    5,933,518 
Lease liabilities, non-current   10,274     
Total Liabilities   2,837,055    5,933,518 
           
Stockholders’ equity          
Series A preferred stock, $0.001 par value; 9,500 shares authorized; 4,080 shares issued and outstanding as of September 30, 2019 and December 31, 2018   2,289,324    2,289,324 
Series B preferred stock, $0.001 par value; 6,000 shares authorized; 1,850 and 5,608 shares issued and outstanding as of September 30, 2019 and December 31, 2018, respectively   1,288,956    3,906,931 
Series C preferred stock, $0.001 par value; 1,880 shares authorized; 240 and 1,880 shares issued and outstanding as of September 30, 2019 and December 31, 2018, respectively   240,000    1,880,000 
Common stock, $0.001 par value; 225,000,000 shares authorized, 9,926,956 and 6,036,562 shares issued and outstanding as of September 30, 2019 and December 31, 2018, respectively   9,927    6,037 
Additional paid-in capital   76,122,975    71,505,160 
Accumulated other comprehensive loss       (923)
Accumulated deficit   (79,888,272)   (70,200,145)
Total stockholders’ equity   62,910    9,386,384 
Total Liabilities and Stockholders’ Equity  $2,899,965   $15,319,902 

 

The accompanying notes are an integral part of these condensed financial statements.

 

1

 

 

RITTER PHARMACEUTICALS, INC.

CONDENSED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS

(Unaudited)

 

  

For the Three Months Ended

September 30,

  

For the Nine Months Ended

September 30,

 
   2019   2018   2019   2018 
Operating costs and expenses:                    
Research and development  $1,036,689   $3,459,681   $6,044,580   $6,180,607 
Patent costs   20,867    59,068    139,436    170,418 
General and administrative   1,122,825    1,144,750    3,621,888    3,957,545 
Total operating costs and expenses   2,180,381    4,663,499    9,805,904    10,308,570 
                     
Operating loss   (2,180,381)   (4,663,499)   (9,805,904)   (10,308,570)
                     
Other income:                    
Interest income   13,172    17,237    117,777    64,965 
Total other income   13,172    17,237    117,777    64,965 
Net loss  $(2,167,209)  $(4,646,262)  $(9,688,127)  $(10,243,605)
                     
Other comprehensive income:                    
Unrealized gain on debt securities           923     
Comprehensive loss   (2,167,209)   (4,646,262)   (9,687,204)   (10,243,605)
                     
Net loss per common share – basic and diluted  $(0.23)  $(0.86)  $(1.09)  $(2.00)
                     
Weighted average common shares outstanding – basic and diluted   9,507,636    5,373,769    8,873,947    5,129,351 

 

The accompanying notes are an integral part of these condensed financial statements.

 

2

 

 

RITTER PHARMACEUTICALS, INC.

CONDENSED STATEMENTS OF CHANGES IN STOCKHOLDERS’ EQUITY

(Unaudited)

 

   Series A
Preferred Stock
   Series B
Preferred Stock
   Series C
Preferred Stock
   Common Stock   Paid-in   Accumulated   Other
Comprehensive
   Total Stockholders’ 
   Shares   Amount   Shares   Amount   Shares   Amount   Shares   Amount   Capital   Deficit   Loss   Equity 
Balance at December 31, 2017   9,140   $5,128,536       $       $    4,940,652   $4,941   $68,323,939   $(53,331,434)  $   $20,125,982 
Conversion of preferred shares into common stock   (320)   (179,555)                   80,000    80    179,475             
Stock-based compensation                                   212,608            212,608 
Net loss                                       (2,012,690)        (2,012,690)
Balance at March 31, 2018   8,820   $4,948,981       $       $    5,020,652   $5,021   $68,716,022   $(55,344,124)  $   $18,325,900 
                                                             
Payout to stockholders for fractional shares                                   (3,256)           (3,256)
Conversion of preferred shares into common stock   (1,260)   (706,998)                   315,000    314    706,683             
Stock-based compensation                                   178,074            178,074 
Net loss                                       (3,584,652)       (3,584,652)
Balance at June 30, 2018   7,560   $4,241,983       $       $    5,334,639   $5,335   $69,597,523   $(58,928,776)  $   $14,916,065 
                                                             
Conversion of preferred shares into common stock   (1,600)   (897,774)                   400,000    400    897,374             
Stock-based compensation                                   171,073            171,073 
Net loss                                       (4,646,263)  $    (4,646,263)
Balance at September 30, 2018   5,960   $3,344,209       $       $    5,734,639   $5,735   $70,665,970   $(63,575,039)  $   $10,440,875 

 

   Series A
Preferred Stock
   Series B
Preferred Stock
   Series C
Preferred Stock
   Common Stock   Paid-in   Accumulated   Other Comprehensive   Total Stockholders’ 
   Shares   Amount   Shares   Amount   Shares   Amount   Shares   Amount   Capital   Deficit   Loss   Equity 
Balance at December 31, 2018   4,080   $2,289,324    5,608   $3,906,931    1,880   $1,880,000    6,036,562   $6,037   $71,505,160   $(70,200,145)  $(923)  $9,386,384 
Stock-based compensation                                   146,491            146,491 
Conversion of Series B preferred shares into common stock           (2,608)   (1,816,732)           2,005,770    2,005    1,814,727             
Conversion of Series C preferred shares into common stock                   (1,640)   (1,640,000)   1,000,000    1,000    1,639,000             
Unrealized gain on investment in marketable securities                                       (923)   2,434    1,511 
Net loss                                      $(4,705,766)  $   $(4,705,766)
Balance at March 31, 2019   4,080   $2,289,324    3,000   $2,090,199    240   $240,000    9,042,332   $9,042   $75,105,378   $(74,906,834)  $1,511   $4,828,620 
                                                             
Stock-based compensation                                   122,703            122,703 
Fractional shares adjustment                           (2)                    
Unrealized gain on investment in marketable securities                                       923    (1,511)   (588)
Net loss                                       (2,815,152)       (2,815,152)
Balance at June 30, 2019   4,080   $2,289,324    3,000   $2,090,199    240   $240,000    9,042,330   $9,042   $75,228,081   $(77,721,063)  $   $2,135,583 
                                                             
Stock-based compensation                                   94,536            94,536 
Conversion of Series B preferred shares into common stock           (1,150)   (801,243)           884,626    885    800,358             
Net loss                                       (2,167,209)       (2,167,209)
Balance at September 30, 2019   4,080   $2,289,324    1,850   $1,288,956    240   $240,000    9,926,956   $9,927   $76,122,975   $(79,888,272)  $   $62,910 

 

The accompanying notes are an integral part of these condensed financial statements.

 

3

 

 

RITTER PHARMACEUTICALS, INC.

CONDENSED STATEMENTS OF CASH FLOWS

(Unaudited)

 

   For the Nine Months Ended
September 30,
 
   2019   2018 
Cash flows from operating activities          
Net loss  $(9,688,127)  $(10,243,605)
Adjustments to reconcile net loss to net cash used in operating activities:          
Depreciation   4,550    4,257 
Amortization of right-of-use assets   78,341     
Stock-based compensation   363,730    561,755 
Settlement of Covance accounts payable       (893,823)
Amortization of discount on available-for-sale debt securities   (9,769)    
Unrealized gain on available-for-sale securities   923     
Changes in operating assets and liabilities:          
Accrued interest receivable   52,987     
Prepaid expenses   (349,677)   (298,384)
Other assets   (10,000)    
Accounts payable   (1,945,831)   786,723 
Accrued expenses   (1,266,621)   (45,692)
Lease liabilities   (68,971)    
Other liabilities   (13,359)   (1,362)
Net cash used in operating activities   (12,851,824)   (10,130,131)
           
Cash flows from (used in) investing activities          
Purchase of property and equipment   (1,589)   (2,008)
Sale of investments in marketable debt securities   6,998,549     
Net cash flows from investing activities   6,996,960    (2,008)
           
Cash flows used in financing activities          
Payout to stockholders for fractional shares       (3,256)
Net cash used in financing activities       (3,256)
           
Net decrease in cash and cash equivalents   (5,854,864)   (10,135,395)
           
Cash and cash equivalents at beginning of period  $7,812,259   $22,631,971 
Cash and cash equivalents at end of period  $1,957,395   $12,496,576 
           
Supplemental disclosure of cash flow activities:          
Cash paid for taxes  $187,079   $ 
           
Supplemental disclosure of non-cash financing activities:          
Conversion of preferred stock to common stock  $4,257,975   $1,784,327 
Right-of-use assets obtained in exchange for lease liabilities  $(198,319)  $ 
Lease liabilities arising from obtaining right-of-use assets  $184,644   $ 

 

The accompanying notes are an integral part of these condensed financial statements.

 

4

 

 

RITTER PHARMACEUTICALS, INC.

NOTES TO UNAUDITED CONDENSED FINANCIAL STATEMENTS

 

NOTE 1 - ORGANIZATION AND PRINCIPAL ACTIVITIES

 

Ritter Pharmaceuticals, Inc. (“Ritter” or the “Company”) is a Delaware corporation headquartered in Los Angeles, California. The Company was formed as a Nevada limited liability company in March 2004, under the name Ritter Natural Sciences, LLC, and converted into a Delaware corporation in September 2008.

 

Since its inception, Ritter Pharmaceuticals, Inc. has been focused on the development of innovative therapeutic products that modulate the gut microbiome to treat gastrointestinal diseases. The Company’s only product candidate, RP-G28, is an orally administered, high purity galacto-oligosaccharide for the treatment of lactose intolerance (“LI”), a condition that affects millions of people worldwide. RP-G28 is designed to selectively stimulate the growth of lactose-metabolizing bacteria in the colon, thereby effectively adapting the gut microbiome to assist in digesting lactose (the sugar found in milk) that reaches the large intestine. The Company completed enrollment in its Phase 3 clinical trial of RP-G28 known as “Liberatus” in March 2019 and last patient visit in July 2019. In September 2019, the Company announced that its Phase 3 clinical trial of RP-G28 for LI failed to demonstrate statistical significance in its pre-specified primary and secondary endpoints. While the Company is continuing to analyze the results of the trial to better understand the data and clinical outcomes to assess a path forward for RP-G28, no further development efforts of RP-G28 are currently ongoing.

 

In October 2019, the Company announced that it has engaged A.G.P./Alliance Global Partners (“A.G.P.”) as financial advisor to explore and evaluate potential strategic alternatives to enhance shareholder value, which may include an acquisition, merger, reverse merger, other business combination, sale of assets, licensing or other strategic transaction.

 

The Company operates in one business segment focused on the development and commercialization of therapeutic products that modulate the gut microbiome to treat gastrointestinal diseases. The Company is not organized by market and is managed and operated as one business. A single management team reports to the chief operating decision maker, the Chief Executive Officer. The Company does not currently operate any separate lines of business or separate business entities.

 

NOTE 2 - BASIS OF PRESENTATION

 

The accompanying interim period unaudited condensed financial statements have been prepared in accordance with accounting principles generally accepted in the United States of America (“GAAP”) and applicable rules and regulations of the U.S. Securities and Exchange Commission (“SEC”) regarding interim financial reporting. Accordingly, they do not include all of the information and footnotes required by GAAP for complete financial statements. However, in the opinion of management, all adjustments consisting of normal recurring adjustments considered necessary for a fair presentation of the financial position and results of operations have been included and management believes the disclosures that are made are adequate to make the information presented not misleading.

 

The condensed balance sheets at December 31, 2018 have been derived from the audited financial statements included in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2018 filed with the SEC on April 1, 2019 (the “2018 Annual Report”), but does not include all of the information and footnotes required by GAAP for complete financial statements.

 

The results for the three and nine months ended September 30, 2019 are not necessarily indicative of the results expected for the full fiscal year or any other period. The accompanying interim period unaudited condensed financial statements and related financial information included in this Quarterly Report on Form 10-Q (“Quarterly Report”) should be read in conjunction with the audited financial statements and notes thereto included in the Company’s 2018 Annual Report.

 

All common share amounts and per share amounts have been adjusted to reflect a 1-for-10 reverse stock split of the Company’s common stock effected on March 23, 2018.

 

5

 

 

Going Concern and Liquidity

 

The accompanying interim period unaudited condensed financial statements have been prepared assuming the Company will continue as a going concern, which contemplates, among other things, the realization of assets and satisfaction of liabilities in the normal course of business.

 

The Company has not generated any product revenue and has not achieved profitable operations to date. For the nine months ended September 30, 2019, the Company had a net loss of approximately $9.7 million and had net cash used in operating activities of approximately $12.9 million. At September 30, 2019, the Company had net working capital of approximately $0.1 million, an accumulated deficit of approximately $79.9 million, and cash and cash equivalents of approximately $2.0 million.

 

In September 2019, the Company announced that its Phase 3 clinical trial of RP-G28 for LI failed to demonstrate statistical significance in its pre-specified primary and secondary endpoints. While the Company is continuing to analyze the results of the trial to better understand the data and clinical outcomes to assess a path forward for RP-G28, no further development efforts of RP-G28 are currently ongoing. The Company is currently exploring and evaluating potential strategic alternatives to enhance shareholder value, which may include an acquisition, merger, reverse merger, other business combination, sale of assets, licensing or other strategic transaction.

 

There is no assurance that profitable operations will ever be achieved, and, if achieved, could be sustained on a continuing basis. The Company’s operating expenses have decreased significantly since the completion of its Phase 3 clinical trial of RP-G28 and the Company has made additional operating expense reductions following the announcement of the trial results, including reductions to executive and board compensation. The Company will continue to make further reductions as necessary. However, any future development activities, clinical and pre-clinical testing, and commercialization of the Company’s products will require significant financing. These matters, among others, raise substantial doubt about the Company’s ability to continue as a going concern.

 

Since inception, the operations of the Company have been funded through the sale of common shares, preferred shares, warrants and convertible debt. Our announcement related to the results of our Phase 3 clinical trial of RP-G28 has significantly depressed our stock price and may severely impair our ability to raise additional funds. Management cannot be certain that additional funding will be available on acceptable terms, or at all. To the extent that the Company is able to raise additional funds by issuing equity securities, the Company’s stockholders may experience significant dilution. Any debt financing, if available, may involve restrictive covenants that could impact the Company’s ability to conduct business. If the Company is not able to raise additional capital on acceptable terms, the Company may have to (i) discontinue the development and/or commercialization of RP-G28; (ii) seek collaborators for the development of RP-G28 on terms that are less favorable than might otherwise be available; or (iii) relinquish or otherwise dispose of rights to RP-G28.

 

The financial statements do not include any adjustments that might be necessary if the Company is unable to continue as a going concern.

 

NOTE 3 - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

 

There have been no material changes in the Company’s significant accounting policies as of and for the nine months ended September 30, 2019, as compared to the significant accounting policies described in the Company’s 2018 Annual Report, except for the recent adoption of the new lease accounting pronouncement as described below.

 

Use of Estimates

 

The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities as of the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates.

 

6

 

 

Cash and Cash Equivalents

 

Cash consists of amounts held in financial institutions that are immediately available to the Company. The funds are maintained at stable financial institutions, generally at amounts in excess of federally insured limits. Cash equivalents include money market funds and held-to-maturity securities with a maturity date of 90 days or less. As of September 30, 2019, cash and cash equivalents consisted of bank deposits, cash and investments in money market funds. The Company has not realized any losses in such accounts and management believes that the Company is not exposed to significant credit risk due to the financial position of the depository institutions at which those deposits are held.

 

Investments in Marketable Securities

 

Investments in marketable securities are held in a custodial account at a financial institution and managed by the Company’s capital advisors based on the Company’s investment guidelines. All of the Company’s investments in marketable securities are classified as available-for-sale debt securities and are carried at fair value. Interest on these securities, as well as the amortization of discounts and premiums, is included in interest income in the statements of operations. The unrealized gains and losses on these securities are excluded from earnings and reported in other comprehensive income until realized, except when the declines in value are considered to be other than temporary. Other than temporary impairment losses related to credit losses are considered to be realized losses. When available-for-sale debt securities are sold, the cost of the securities is specifically identified and is used to determine the realized gain or loss. Securities classified as current assets have maturity dates of less than or equal to one year from the balance sheet date.

 

Operating Leases

 

The Company determines if a contract contains a lease at inception. The Company’s material operating lease relates to a single office space. Operating lease assets and liabilities are recognized at the lease commencement date. Operating lease liabilities represent the present value of lease payments not yet paid. Operating lease assets represent the Company’s right to use an underlying asset and are based upon the operating lease liabilities adjusted for prepayments or accrued lease payments, initial direct costs, lease incentives, and impairment of operating lease assets. To determine the present value of lease payments not yet paid, the Company estimates incremental secured borrowing rates corresponding to the maturities of the leases. As the Company has no outstanding debt or committed credit facilities, secured or otherwise, the Company estimates this rate based on prevailing financial market conditions, comparable company and credit analysis, and management judgment.

 

The Company’s leases typically contain rent escalations over the lease term. The Company recognize expense for these leases on a straight-line basis over the lease term. Additionally, tenant incentives used to fund leasehold improvements are recognized when earned and reduce the Company’s right-of-use (“ROU”) asset related to the lease. These are amortized through the ROU asset as reductions of expense over the lease term. The Company’s lease agreement does not contain any material residual value guarantees or material restrictive covenants. The Company has no lease agreements with lease and non-lease components.

 

Related to the adoption of Topic 842, the Company’s policy elections were as follows:

 

Separation of lease and non-lease components   While the Company does not currently have any lease agreement with lease and non-lease components, the Company elected this expedient to account for lease and non-lease components as separate components.
     
Short-term policy   The Company has elected the short-term lease recognition exemption for all applicable classes of underlying assets. Short-term disclosures include only those leases with a term greater than one month and 12 months or less, and expense is recognized on a straight-line basis over the lease term. Leases with an initial term of 12 months or less, that do not include an option to purchase the underlying asset that the Company is reasonably certain to exercise, are not recorded on the balance sheet.

 

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Other information related to the Company’s leases is provided below.

 

   Nine Months Ended
September 30, 2019
 
Supplemental Cash Flows Information     
Cash paid for amounts included in the measurement of lease liability:     
Operating cash flows from operating lease   86,234 
Operating lease asset obtained in exchange for lease obligation:     
Operating lease  $198,319 
Remaining lease term     
Operating lease   1.1 years  
Discount rate     
Operating lease   6.00%

 

Future payments under non-cancelable extended operating leases having initial or remaining terms of one year or more are as follows for the remaining fiscal year and thereafter:

 

Future minimum lease payments year ending December 31,    
2019 (remaining)  $30,675 
2020   103,254 
Total future minimum lease payments, undiscounted   133,929 
Less imputed interest   (4,581)
Present value of lease liabilities  $129,348 
      
Operating lease liabilities reported as of September 30, 2019:     
Operating lease liabilities-current  $119,074 
Operating lease liabilities-non-current   10,274 
Total  $129,348 

 

Equity-linked Financial Instruments

 

The Company classifies outstanding common stock warrants with down-round features as equity, if the instrument would otherwise be classified in equity absent the down-round feature. The Company will recognize the value of a down-round feature when it is triggered and the warrant’s strike price has been adjusted downward, as a deemed dividend and reduction of income available to common stockholders in computing basic earnings per share.

 

Net Loss Per Share

 

The Company determines basic loss per share and diluted loss per share in accordance with the provisions of Accounting Standards Codification (“ASC”) 260, “Earnings per Share.” Basic net loss per share was calculated by dividing net loss by the weighted-average common shares outstanding during the period. Diluted net loss per share was calculated by dividing net loss by the weighted-average common shares outstanding during the period using the treasury stock method or the two-class method, whichever is more dilutive. The potentially dilutive stock options issued under the 2015 Plan (described in Note 8), Series A, B and C Convertible Preferred Stock (described in Note 6) and warrants to purchase the Company’s common stock (described in Notes 6 and 7) were not considered in the computation of diluted net loss per share because they would be anti-dilutive.

 

Comprehensive Income (Loss)

 

Comprehensive income (loss) is defined as the change in equity during a period from transactions and other events and circumstances from non-owner sources. The Company is required to record all components of comprehensive income (loss) in the financial statements in the period in which they are recognized. Net income (loss) and other comprehensive income (loss), including foreign currency translation adjustments and unrealized gains and losses on investments are reported, net of their related tax effect, to arrive at comprehensive income (loss). For the nine months ended September 30, 2019, comprehensive income consisted of unrealized gains on investments in available-for-sale debt securities. There were no unrealized gains (losses) on investments in available-for-sale debt securities and held-to-maturity debt securities for the nine months ended September 30, 2018.

 

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Recent Accounting Pronouncements

 

In June 2016, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) No. 2016-13, Financial Instruments – Credit Losses (Topic 326): Measurement of Credit Losses on Financial Instruments, an amendment that modifies the measurement recognition of credit losses for most financial assets and certain other instruments. The amendment updates the guidance for measuring and recording credit losses on financial assets measured at amortized cost by replacing the “incurred loss” model with an “expected loss” model. Accordingly, these financial assets will be presented at the net amount expected to be collected. The amendment also requires that credit losses related to available-for-sale debt securities be recorded as an allowance through net income rather than reducing the carrying amount under the current, other-than-temporary-impairment model. The guidance is effective for public business entities that are SEC filers. The amendments in ASU No. 2016-13 are effective for fiscal years beginning after December 15, 2019, including interim periods within those fiscal years. For all other public business entities, the amendments in this ASU are effective for fiscal years beginning after December 15, 2020, including interim periods within those fiscal years. The Company does not expect the adoption of this guidance will have a material impact on its financial statements.

 

In August 2018, the FASB issued ASU No. 2018-13, “Fair Value Measurement (Topic 820): Disclosure Framework — Changes to the Disclosure Requirements for Fair Value Measurement”, an amendment to the accounting guidance on fair value measurements. The guidance modifies the disclosure requirements on fair value measurements, including the removal of disclosures of the amount of and reasons for transfers between Level 1 and Level 2 of the fair value hierarchy, the policy for timing of transfers between levels, and the valuation processes for Level 3 fair value measurements. The guidance also adds certain disclosure requirements related to Level 3 fair value measurements. The guidance is effective for fiscal years, and interim periods within those fiscal years, beginning after December 15, 2019. The Company does not expect the adoption of this guidance will have a material impact on its financial statements.

 

In June 2016, the FASB issued ASU 2016-13, Financial Instruments—Credit Losses (Topic 326): Measurement of Credit Losses on Financial Instruments (ASU 2016-13) and also issued subsequent amendments to the initial guidance: ASU 2018-19, ASU 2019-04, and ASU 2019-05 (collectively, “Topic 326”). Topic 326 requires measurement and recognition of expected credit losses for financial assets held. The effective date and transition methodology for the amendments in Topic 326 are the same as in ASU 2016-13. The Company does not expect the adoption of this guidance will have a material impact on its financial statements.

 

Other accounting standard updates effective after September 30, 2019 are not expected to have a material impact on the Company’s financial statements.

 

Recently Adopted Accounting Pronouncements

 

In February 2016, the FASB issued ASU No. 2016-02, Leases (Topic 842). Under this guidance, an entity is required to recognize ROU assets and corresponding lease liabilities on its balance sheets and disclose key information about leasing arrangements. In July 2018, the FASB issued ASU No. 2018-11, Leases (Topic 842) Targeted Improvements, which provides for an alternative transition method by allowing companies to continue to use the legacy guidance in Topic 840, Leases, including its disclosure requirements, in the comparative periods presented in the year of adoption of the new leases standard and recognize a cumulative-effect adjustment to the opening balance of retained earnings in the period of adoption rather than the earliest period presented.

 

The Company elected the available package of practical expedients, but not the hindsight practical expedient, and implemented internal controls to enable the preparation of financial information on adoption as of January 1, 2019.

 

The standard had a material impact on the Company’s condensed balance sheets, but did not have an impact on its statements of operations and comprehensive loss. The most significant impact was the recognition of a ROU asset and lease liability for the Company’s sole operating lease—the Company had no finance leases. Adoption of the standard did not require the Company to restate previously reported results as it elected to apply a modified retrospective approach at the beginning of the period of adoption rather than at the beginning of the earliest comparative period presented.

 

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In June 2018, the FASB issued ASU No. 2018-07, Improvements to Nonemployee Share-Based Payment Accounting, which expands the scope of Topic 718 Compensation—Stock Compensation, to include share-based payments issued to nonemployees for goods or services. Consequently, the accounting for share-based payments to nonemployees and employees will be substantially aligned. ASU No. 2018-07 supersedes Subtopic 505-50 Equity—Equity-Based Payments to Non-Employees. The amendments implemented by ASU No. 2018-07 are effective for fiscal years beginning after December 15, 2018, including interim periods within that fiscal year. Early adoption is permitted, but no earlier than an entity’s adoption date of Topic 606. The Company adopted ASU 2018-07 on January 1, 2019 and it did not have a material effect on its results of operations, financial position or cash flows.

 

In August 2018, the SEC adopted final rules under SEC Release No. 33-10532, Disclosure Update and Simplification, amending certain SEC disclosure requirements that were redundant, duplicative, overlapping, outdated or superseded. In addition, the amendments expanded the disclosure requirements on the analysis of stockholders’ equity for interim financial statements. Under the amendments, an analysis of changes in each caption of stockholders’ equity presented in the balance sheets must be provided in a note or separate statement. The analysis must present a reconciliation of the beginning balance to the ending balance of each period for which a statement of comprehensive income is required to be filed. These final rules became effective on November 5, 2018, with issuers required to provide their analysis of stockholders’ equity in quarterly reports on Form 10-Q beginning with reports for the quarter ended March 31, 2019. The Company included the analysis of changes in stockholders’ equity in the interim period unaudited condensed financial statements for the quarter ended March 31, 2019, has included it in this Quarterly Report, and will continue to do so in the Company’s quarterly reports on Form 10-Q in the future. The Company adopted these SEC amendments on January 1, 2019 and it did not have a material impact on the Company’s financial position, results of operations, cash flows or stockholders’ equity.

 

NOTE 4 - PROPERTY AND EQUIPMENT

 

Property and equipment consists of the following:

 

   Estimated Life  September 30, 2019   December 31, 2018 
Computers and equipment  5 years  $17,178   $15,589 
Furniture and fixtures  7 years   19,158    19,158 
Total property and equipment      36,336    34,747 
Accumulated depreciation      (19,137)   (14,587)
Total property and equipment, net     $17,199   $20,160 

 

Depreciation expense of approximately $1,600 was recognized for the three months ended September 30, 2019 and approximately $1,500 was recognized for the three months ended September 30, 2018. Depreciation expense of approximately $4,600 was recognized for the nine months ended September 30, 2019 and approximately $4,300 was recognized for 2018. Depreciation expense is classified in general and administrative expense in the accompanying unaudited condensed statements of operations.

 

NOTE 5 - COMMITMENTS AND CONTINGENCIES

 

Master Services Agreement

 

In May 2018, the Company entered into an Amended and Restated Master Services Agreement (“Service Agreement”) with a clinical research organization (“CRO”), pursuant to which the CRO will perform certain services related to the management and execution of certain clinical trials involving RP-G28. The Services Agreement supersedes the Master Service Agreement, dated August 30, 2016, by and between the Company and the CRO. The precise services to be performed by the CRO under the Services Agreement will be mutually agreed upon by the parties in writing and set forth in one or more task orders. The Company is not obligated to purchase any minimum or specific volume or dollar amount of services under the Services Agreement.

 

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The term of the Services Agreement is four years from the effective date of the Service Agreement unless earlier terminated. The Company may terminate the Services Agreement or any task without cause immediately upon giving the CRO notice of such termination. The CRO may terminate a task order if the Company has materially defaulted on its obligations under the Services Agreement or any task order and has not cured such material default with advance notice to the Company, as described in the Services Agreement.

 

Lease Agreement

 

On July 9, 2015, the Company entered into a lease with a California limited partnership, pursuant to which the Company leased approximately 2,780 square feet of office space in Los Angeles, California for its headquarters. The lease provides for a term of sixty-one (61) months, commencing on October 1, 2015. The Company paid no rent for the first month of the term and paid base rent of $9,174 per month for months 2 through 13 of the term, with increasing base rent for each twelve-month period thereafter under the term of the lease to a maximum of $10,325 per month for months 50 through 61. The base rent payments do not include the Company’s proportionate share of any operating expenses, including real estate taxes. The Company has the option to extend the term of the lease for one five-year term, provided that the rent would be subject to market adjustment at the beginning of the renewal term.

 

Rent expense, which is recognized on a straight-line basis over the lease term, was approximately $29,000 for each of the three months ended September 30, 2019 and 2018, and approximately $88,000 for each of the nine months ended September 30, 2019 and 2018 and is recorded in general and administrative expenses in the accompanying unaudited condensed statements of operations.

 

Legal

 

From time to time, the Company may be party to legal claims and proceedings that arise in the ordinary course of business, which may relate to our operations or assets. These may include disputes and lawsuits related to intellectual property, licensing, contract law and employee relations matters. Periodically, the Company reviews the status of significant matters, if any exist, and assesses its potential financial exposure. If the potential loss from any claim or legal claim is considered probable and the amount can be estimated, the Company accrues a liability for the estimated loss. Legal proceedings are subject to uncertainties, and the outcomes are difficult to predict. Because of such uncertainties, accruals are based on the best information available at the time. As additional information becomes available, the Company reassesses the potential liability related to pending claims and litigation. We do not believe that any individual legal claim or proceeding that is currently pending is material to the Company or that these claims and proceedings in the aggregate are material to the Company.

 

NOTE 6 - STOCKHOLDERS’ EQUITY

 

Authorized Shares

 

The Company’s Amended and Restated Certificate of Incorporation authorizes the issuance of up to 225,000,000 shares of common stock, $0.001 par value per share, and 15,000,000 shares of preferred stock, $0.001 par value per share, of which 9,500, 6,000 and 1,880 shares are designated for Series A, B and C, respectively.

 

All common share amounts and per share amounts were retroactively restated to reflect a 1-for-10 reverse stock split that was effective March 23, 2018.

 

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As of September 30, 2019, the Company had 9,926,956 shares of common stock, 4,080 shares of Series A convertible preferred stock, 1,850 shares of Series B convertible preferred stock and 240 shares of Series C convertible preferred stock issued and outstanding. Each share of the Company’s common stock is entitled to one vote, and all shares rank equally as to voting and other matters. Each share of Series A preferred stock is convertible by the holder at $4.00 per share, subject to adjustment for stock splits, stock dividends, subsequent rights offerings, pro rata distributions, and fundamental transactions. Each share of Series B preferred stock is convertible by the holder at $1.30 per share, subject to customary adjustment in the event of future stock dividends and stock splits. Each share of Series C preferred stock is convertible by the holder at $1.64 per share, subject to customary adjustment in the event of future stock dividends and stock splits. Holders are entitled to receive, and the Company shall pay, dividends on outstanding shares of Series A, Series B and Series C preferred stock, on an as-if-converted-to-common-stock basis, equal to and in the same form as dividends actually paid on outstanding common shares when, as and if such dividends are paid on outstanding common shares. Upon any liquidation, dissolution or winding-up of the Company, whether voluntary or involuntary, the holders of Series A, Series B and Series C preferred stock shall be entitled to receive out of the assets of the Company, whether capital or surplus, the same amount that a holder of common stock would receive if the Series A, Series B and Series C preferred stock were fully converted to common stock, which amounts shall be paid pari passu with all common stockholders. Holders of Series A, Series B and Series C preferred stock have no voting rights. However, as long as any shares of Series A, Series B and Series C preferred stock are outstanding, the Company may not, without the affirmative vote of the holders of a majority of the then outstanding shares of Series A, Series B and Series C preferred stock, (a) alter or change adversely the powers, preferences or rights given to the Series A, Series B and Series C preferred stock or alter or amend the applicable Certificate of Designation, (b) amend the Company’s certificate of incorporation or other charter documents in any manner that adversely affects any rights of the holders of Series A, Series B and Series C preferred stock, (c) increase the number of authorized shares of Series A, Series B and Series C preferred stock, or (d) enter into any agreement with respect to any of the foregoing.

 

Aspire Capital Common Stock Purchase Agreement

 

On May 4, 2017, the Company entered into a common stock purchase agreement with Aspire Capital Fund, LLC (“Aspire Capital”), which the Company and Aspire amended and restated on March 29, 2019 and July 23, 2019 (as amended and restated, the “Aspire Purchase Agreement”). The Aspire Purchase Agreement was amended and restated to adjust certain provisions of the agreement to improve the Company’s access to funding under the agreement. The Aspire Purchase Agreement provides access to the Company of up to an aggregate of $6.5 million in proceeds through the sale of shares of its common stock through March 31, 2021.

 

Under the Aspire Purchase Agreement, as amended, on any trading day the Company selects, it has the right, in its sole discretion, to present Aspire Capital with a purchase notice (each, a “Purchase Notice”), directing Aspire Capital (as principal) to purchase up to 100,000 shares of its common stock per trading day for up to an aggregate of $6,500,000 of its common stock, at a per share price (the “Purchase Price”) equal to the lesser of: (i) the lowest sale price of the Company’s common stock on the sale date, or (ii) the arithmetic average of the three lowest closing sale prices for the Company’s common stock during the ten (10) consecutive trading days ending on the trading day immediately preceding the sale date. The aggregate purchase price payable by Aspire Capital on any one purchase date cannot exceed $500,000. In addition, on any date on which the Company submits a Purchase Notice to Aspire Capital in an amount of at least 100,000 shares and its stock price is not less than $0.25 per share, the Company can also, in its sole discretion, present Aspire Capital with a volume-weighted average price purchase notice (each, a “VWAP Purchase Notice”) directing Aspire Capital to purchase an amount of its common stock equal to up to 30% of the aggregate shares of the Company’s common stock traded on its principal market on the next trading day (the “VWAP Purchase Date”), as determined by the Company. Under the terms of the Aspire Purchase Agreement, the number of shares that can be sold pursuant to Aspire Capital is limited to 1,807,562 (the “Exchange Cap”), which represented 19.99% of the Company’s outstanding shares of common stock as of March 29, 2019, the date the agreement was first amended and restated, unless stockholder approval or an exception pursuant to the rules of the Nasdaq Capital Market was obtained to issue more than 19.99%. This limitation would not apply if, at any time the Exchange Cap was reached and at all times thereafter, the average price paid for all shares issued under the Aspire Purchase Agreement was equal to or greater than $0.86 (the “Minimum Price”), which was the closing price of the Company’s common stock immediately preceding the signing of the agreement. As of September 30, 2019, no shares of common stock have been sold or issued to Aspire Capital under the Aspire Purchase Agreement.

 

NOTE 7 - WARRANTS

 

Warrants to purchase an aggregate of 8,413,017 shares of the Company’s common stock were outstanding at September 30, 2019. These warrants are all vested and exercisable, have exercise prices ranging from $1.30 to $93.00 per share, with a weighted average exercise price of $1.78, and expire at various dates through November 2023.

 

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NOTE 8 - STOCK-BASED COMPENSATION

 

Equity Incentive Plans

 

The Company has issued equity awards pursuant to its 2015 Equity Incentive Plan (the “2015 Plan”), 2009 Stock Plan and 2008 Stock Plan (collectively the “Plans”). The Plans permit the Company to grant non-statutory stock options, incentive stock options and other equity awards to the Company’s employees, outside directors and consultants; however, incentive stock options may only be granted to the Company’s employees. Beginning June 29, 2015, no further awards may be granted under the 2008 Stock Plan or 2009 Stock Plan. However, to the extent awards under the 2008 Plan or 2009 Plan are forfeited or lapse unexercised or are settled in cash, the common stock subject to such awards will be available for future issuance under the 2015 Plan.

 

On June 2, 2017, the stockholders of the Company approved an amendment to the 2015 Plan at the 2017 annual meeting of stockholders, which among other things, increased the number of shares that may be issued pursuant to awards under the 2015 Plan by 83,800 shares of common stock.

 

On September 15, 2017, the stockholders of the Company approved an amendment to the 2015 Plan at a special meeting of stockholders, which among other things, increased the number of shares that may be issued pursuant to awards under the 2015 Plan by 2,585,871 shares of common stock. As of September 30, 2019, the aggregate number of shares of common stock authorized for issuance under the 2015 Plan, as amended, was 2,750,000 and 183,124 shares were available for issuance as of September 30, 2019.

 

The following represents a summary of the options granted to employees and non-employees that are outstanding at September 30, 2019 and changes during the period then ended:

 

   Options   Weighted Average Exercise Price   Aggregate Intrinsic Value   Weighted Average Remaining Contractual
Life (in years)
 
Outstanding at December 31, 2018   673,885   $19.82   $―     8.2 
Granted   698,750   $0.62   $―     9.0 
Exercised/ Expired/ Forfeited   (28,500)  $0.98   $―     ―  
Outstanding at September 30, 2019   1,344,135   $10.24   $―     8.4 
Exercisable at September 30, 2019   531,528   $28.66   $―     7.4 

 

The exercise price for an option issued under the 2015 Plan is determined by the Board of Directors, but will be (i) in the case of an incentive stock option (A) granted to an employee who, at the time of grant of such option, is a 10% stockholder, no less than 110% of the fair market value per share on the date of grant; or (B) granted to any other employee, no less than 100% of the fair market value per share on the date of grant; and (ii) in the case of a non-statutory stock option, no less than 100% of the fair market value per share on the date of grant. The options awarded under the Plans will vest as determined by the Board of Directors but will not exceed a ten-year period.

 

Fair Value of Equity Awards

 

The Company utilizes the Black-Scholes option pricing model to value awards under its Plans. Key valuation assumptions include:

 

Expected dividend yield. The expected dividend is assumed to be zero as the Company has never paid dividends and has no current plans to pay any dividends on the Company’s common stock.
   
Expected stock-price volatility. As the Company’s common stock only recently became publicly traded, the expected volatility is derived from the average historical volatilities of publicly traded companies within the Company’s industry that the Company considers to be comparable to the Company’s business over a period approximately equal to the expected term and the Company.

 

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Risk-free interest rate. The risk-free interest rate is based on the U.S. Treasury yield in effect at the time of grant for zero coupon U.S. Treasury notes with maturities approximately equal to the expected term.
   
Expected term. The expected term represents the period that the stock-based awards are expected to be outstanding. The Company’s historical share option exercise experience does not provide a reasonable basis upon which to estimate an expected term because of a lack of sufficient data. Therefore, the Company estimates the expected term by using the simplified method provided by the SEC. The simplified method calculates the expected term as the average of the time-to-vesting and the contractual life of the options.

 

The material factors incorporated in the Black-Scholes model in estimating the fair value of the options granted for the periods presented were as follows (three months ended September 30, 2018 stock price adjusted for 1-for-10 reverse stock split):

 

   For the three months ended September 30,   For the nine months ended September 30, 
   2019   2018   2019   2018 
Expected dividend yield   0.00%   0.00%   0.00%   0.00%
Expected stock-price volatility   69.00% – 69.38%   48.89% – 50.22%   46.33% – 69.38%   46.47% – 53.11 %
Risk-free interest rate  1.47% – 1.54%   2.78% – 3.07%   1.47% – 2.60%   2.46% – 3.07%
Expected average term of options   5 –7    7 – 10    5 – 7    5 – 10 
Stock price  $1.04   $1.85 – $2.22   $0.60 – $1.04   $1.85 – $3.40 

 

Restricted Stock Units

 

Certain employees and consultants have been awarded restricted stock units. The restricted stock units include either milestone or time-based vesting. The following table summarizes restricted stock unit activity for the nine months ended September 30, 2019:

 

   Number of
Units
  

Weighted Average

Grant Date

Fair Value

 
Unvested at December 31, 2018   1,100,000   $2.73 
Granted   35,000    0.63 
Forfeited        
Expired   (35,000)   0.63 
Unvested at September 30, 2019   1,100,000   $2.73 

 

Stock-Based Compensation

 

The Company recognized stock-based compensation expense for services within general and administrative expense in the accompanying statements of operations of approximately $95,000 and $171,000 for the three months ended September 30, 2019 and 2018, respectively, and $364,000 and $562,000 for the nine months ended September 30, 2019 and 2018, respectively. As of September 30, 2019, there was approximately $334,000 of total unrecognized compensation cost related to unvested stock-based compensation arrangements. This cost is expected to be recognized over a weighted average period of 1.46 years.

 

No stock options were exercised during the nine months ended September 30, 2019.

 

NOTE 9 - RELATED PARTY TRANSACTIONS

 

A director of the Company is a managing director of Javelin Venture Partners GP, LLC, the general partner of Javelin Venture Partners GP, L.P., which holds a significant investment in the Company’s common stock and warrants. Two directors of the Company have acted as a managing director of Stonehenge Partners, LLC, which holds an investment in the Company’s common stock.

 

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Other than as described above, the Company has not entered into or been a participant in any transaction in which a related party had or will have a direct or indirect material interest for the nine months ended September 30, 2019.

 

NOTE 10 – SUBSEQUENT EVENTS

 

In October 2019, the Company announced that it has engaged A.G.P as financial advisor to explore and evaluate strategic alternatives to enhance shareholder value, which may include an acquisition, merger, reverse merger, other business combination, sale of assets, licensing or other strategic transactions.

 

On November 6, 2019, the Company entered into a Sales Agreement (the “ATM Agreement”) with A.G.P., pursuant to which the Company may offer and sell, from time to time through A.G.P., shares of the Company’s common stock having an aggregate offering price of up to $3,673,159 (the “Placement Shares”), subject to the terms and conditions of the ATM Agreement. Unless earlier terminated pursuant to the terms of the ATM Agreement, the ATM Agreement will automatically terminate upon the earlier to occur of (i) issuance and sale of all of the Placement Shares to or through A.G.P. and (ii) August 1, 2022.

 

On November 12, 2019, we entered into an irrevocable consent and waiver agreement (the “Waiver Agreement”) with the holders of our outstanding Series B convertible preferred stock (the “Series B Holders”), who are also parties to that certain Securities Purchase Agreement, dated as of October 30, 2018 (the “2018 Purchaser Agreement”), by and among the Company and the purchasers identified therein (including the Series B Holders). Pursuant to the terms of the Waiver Agreement, the Series B Holders agreed to waive the restriction in Section 4.12(b) of the 2018 Purchase Agreement prohibiting Dilutive Issuances (as defined in the 2018 Purchase Agreement) for the remainder of the Restricted Period (as defined in the 2018 Purchase Agreement), such that Section 4.12(b) of the 2018 Purchase Agreement is of no further force and effect (the “Waiver”). In exchange for the Series B Holders’ Waiver and subject to the other terms and conditions described in the Waiver Agreement, we agreed to reduce the conversion price of the Series B convertible preferred stock from $1.30 to $0.20 per share and to reduce the conversion price of the Series C convertible preferred stock from $1.64 to $0.20 per share, in each case subject to the approval of our stockholders to issue the additional shares of common stock that will be issuable upon conversion of the Series B convertible preferred stock and Series C convertible preferred stock as a result of the Series B Conversion Price Adjustment and the Series C Conversion Price Adjustment as required by the applicable Nasdaq rules, which stockholder approval we agreed to seek by no later than the earlier of (i) our next annual or special meeting of stockholders, or (ii) February 14, 2020.

 

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ITEM 2. MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

 

The following discussion and analysis should be read in conjunction with our interim unaudited condensed financial statements and related notes included in this Quarterly Report on Form 10-Q (“Quarterly Report”) and the audited financial statements and notes thereto as of and for the year ended December 31, 2018 and the related Management’s Discussion and Analysis of Financial Condition and Results of Operations, both of which are contained in our Annual Report on Form 10-K for the fiscal year ended December 31, 2018 filed with the Securities and Exchange Commission (“SEC”) on April 1, 2019 (the “2018 Annual Report”). As used in this report, unless the context suggests otherwise, “we,” “us,” “our,” or “Ritter” refer to Ritter Pharmaceuticals, Inc. All common share amounts and per share amounts have been adjusted to reflect a 1-for-10 reverse stock split of our common stock on March 23, 2018. In addition to historical information, this discussion and analysis contains forward-looking statements that involve risks, uncertainties and assumptions.

 

Special Note Regarding Forward-Looking Statements and Industry Data

 

This Quarterly Report contains forward-looking statements that involve substantial risks and uncertainties. All statements other than statements of historical facts contained in this Quarterly Report, including statements regarding our strategy, future operations, future financial position, future revenue, projected costs, prospects, plans, objectives of management and expected market growth are forward-looking statements. The words “anticipate,” “believe,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will,” “would” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. These statements involve known and unknown risks, uncertainties and other important factors that may cause our actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements.

 

Some of the factors that we believe could cause actual results to differ from those anticipated or predicted include:

 

our ability to identify a path forward for RP-G28;
   
our ability to obtain additional financing on acceptable terms;

 

 our ability to execute a strategic transaction;
   
the accuracy of our estimates regarding expenses and capital requirements;
   
the success and timing of our preclinical studies and clinical trials;
   
our ability to obtain and maintain regulatory approval of RP-G28 or any other product candidates we may develop in the future, and the labeling under any approval we may obtain;
   
regulatory developments in the United States and other countries;
   
the performance of third-party manufacturers;
   
our ability to develop and commercialize RP-G28 and any other product candidates we may develop in the future;
   
our ability to obtain and maintain intellectual property protection for RP-G28 and any other product candidates that we may develop in the future;
   
the successful development of our sales and marketing capabilities;
   
the potential markets for RP-G28 and any other product candidates we may develop in the future and our ability to serve those markets;

 

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the rate and degree of market acceptance of our products, if approved;
   
the success of competing drugs that are or become available; and
   
the loss of key scientific or management personnel.

 

By their nature, forward-looking statements involve risks and uncertainties because they relate to events, competitive dynamics, and healthcare, regulatory and scientific developments and depend on the economic circumstances that may or may not occur in the future or may occur on longer or shorter timelines than anticipated. Although we believe that we have a reasonable basis for each forward-looking statement contained in this Quarterly Report, we caution you that forward-looking statements are not guarantees of future performance and that our actual results of operations, financial condition and liquidity, and the development of the industry in which we operate may differ materially from the forward-looking statements contained in this Quarterly Report. In addition, even if our results of operations, financial condition and liquidity, and the development of the industry in which we operate are consistent with the forward-looking statements contained in this Quarterly Report, they may not be predictive of results or developments in future periods.

 

Any forward-looking statement that we make in this Quarterly Report speaks only as of the date of such statement, and we undertake no obligation to update such statements to reflect events or circumstances after the date of this Quarterly Report. You should also read carefully the factors described in the “Risk Factors” section of our 2018 Annual Report and this Quarterly Report to better understand the risks and uncertainties inherent in our business and underlying any forward-looking statements.

 

Overview

 

Since our inception, Ritter Pharmaceuticals, Inc. has been focused on the development of innovative therapeutic products that modulate the gut microbiome to treat gastrointestinal diseases. Our only product candidate, RP-G28, is an orally administered, high purity galacto-oligosaccharide for the treatment of lactose intolerance (“LI”), a condition that affects millions of people worldwide. RP-G28 is designed to selectively stimulate the growth of lactose-metabolizing bacteria in the colon, thereby effectively adapting the gut microbiome to assist in digesting lactose (the sugar found in milk) that reaches the large intestine. We completed enrollment in our Phase 3 clinical trial of RP-G28 known as “Liberatus” in March 2019 and last patient visit in July 2019. In September 2019, we announced that our Phase 3 clinical trial of RP-G28 for LI failed to demonstrate statistical significance in its pre-specified primary and secondary endpoints. While we are continuing to analyze the results of the trial to better understand the data and clinical outcomes to assess a path forward for RP-G28, no further development efforts for RP-G28 are currently ongoing.

 

In October 2019, we announced that we had engaged A.G.P./Alliance Global Partners (“A.G.P.”) as financial advisor to explore and evaluate strategic alternatives to enhance shareholder value, which may include an acquisition, merger, reverse merger, other business combination, sale of assets, licensing or other strategic transaction.

 

We have devoted substantially all of our resources to development efforts relating to RP-G28, including conducting clinical trials of RP-G28, providing general and administrative support for these operations and protecting our intellectual property. We currently do not have any products approved for sale and we have not generated any revenue from product sales since our inception.

 

Financial Overview

 

We have incurred net losses in each year since our inception, including net losses of approximately $9.7 million for the nine months ended September 30, 2019. We had an accumulated deficit of approximately $79.9 million as of September 30, 2019. Substantially all of our net losses resulted from costs incurred in connection with our research and development programs, patent costs, stock-based compensation, and from general and administrative costs associated with our operations.

 

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Our operating expenses have decreased significantly since the completion of our Phase 3 clinical trial of RP-G28 and we have made additional operating expense reductions following the announcement of the trial results, including reductions to executive and board compensation. We will continue to make further expense reductions as necessary.

 

However, any future development activities, clinical and pre-clinical testing, and commercialization of the Company’s products will require significant financing.

 

Revenue

 

We do not expect to generate revenue from product sales unless and until we successfully complete development and obtain marketing approval for one or more product candidates, which we expect will take a number of years and is subject to significant uncertainty. Accordingly, we will need to raise additional capital to pursue any future development activities, clinical and pre-clinical testing and commercialization activities. Until such time, if ever, as we can generate substantial revenue from product sales, we expect to finance our operating activities through a combination of equity offerings, debt financings, government or other third-party funding, commercialization, marketing and distribution arrangements and other collaborations, strategic alliances and licensing arrangements. However, we may be unable to raise additional funds or enter into such other arrangements when needed on favorable terms or at all. Our failure to raise capital or enter into such other arrangements as and when needed would have a negative impact on our financial condition and our ability to develop our product candidates.

 

Research and Development Expenses

 

Since our inception, we have focused our resources on our research and development activities, including conducting nonclinical studies and clinical trials, manufacturing development efforts and activities related to regulatory filings for RP-G28. Our research and development expenses have consisted primarily of:

 

fees paid to consultants and clinical research organizations (“CROs”), including in connection with our nonclinical and clinical trials, and other related clinical trial fees, such as for investigator grants, patient screening, laboratory work, clinical trial database management, clinical trial material management and statistical compilation and analysis;
   
costs related to acquiring and manufacturing clinical trial materials;
   
depreciation of equipment, computers and furniture and fixtures;
   
costs related to compliance with regulatory requirements; and
   
overhead expenses for personnel in research and development functions.

 

From inception through September 30, 2019, we have incurred approximately $39.5 million in research and development expenses. Research and development expenses have been significantly reduced with the completion of our Phase 3 clinical trial of RP-G28 and our decision to suspend development efforts of RP-G28 as we continue to analyze the results from our Phase 3 clinical trial to better understand the data and clinical outcomes to assess a path forward for RP-G28.

 

We expect that our research and development expenses will increase if we resume clinical development of RP-G28 or commence clinical development of another product candidate.

 

Patent Costs

 

Patent costs consist primarily of professional fees for legal services to prosecute patents and maintain patent rights.

 

General and Administrative Expenses

 

General and administrative expenses include facilities costs, salaries, benefits, and stock-based compensation for employees, professional fees for directors, fees for independent contractors, insurance and accounting and legal services.

 

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We expect that our general and administrative expenses will increase if we resume clinical development of RP-G28 and/or if we pursue a strategic transaction. These increases may include increased fees for outside consultants, lawyers and accountants, among other expenses.

 

Interest Income and Interest Expense

 

Interest income consists of interest earned on our cash, cash equivalents and short-term investments in marketable debt securities.

 

Critical Accounting Policies and Estimates

 

This discussion and analysis is based on our financial statements, which have been prepared in accordance with accounting principles generally accepted in the United States of America (“GAAP”). The preparation of these financial statements requires us to make estimates and judgments that affect the reported amounts of assets, liabilities, revenues and expenses and the disclosure of contingent assets and liabilities in our financial statements. On an ongoing basis, we evaluate our estimates and judgments, including those related to fair value of financial instruments, research and development costs, accrued expenses and stock-based compensation. We base our estimates on historical experience, known trends and events and various other factors we believe to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and liabilities that are not readily apparent from other sources. Actual results may differ from these estimates under different assumptions or conditions.

 

A critical accounting policy is one that is both important to the portrayal of our financial condition and results of operation and requires management’s most difficult, subjective or complex judgments, often as a result of the need to make estimates about the effect of matters that are inherently uncertain. Our critical accounting estimates are disclosed in the Management’s Discussion and Analysis of Financial Condition and Results of Operations section of our 2018 Annual Report. There have not been any material changes to such critical accounting estimates since December 31, 2018.

 

Fair Value of Financial Instruments

 

The fair value of our financial instruments reflects the amounts that we estimate we would receive in connection with the sale of an asset or pay in connection with the transfer of a liability in an orderly transaction between market participants at the measurement date (exit price). We disclose and recognize the fair value of its assets and liabilities using a hierarchy that prioritizes the inputs to valuation techniques used to measure fair value. The hierarchy gives the highest priority to valuations based upon unadjusted quoted prices in active markets for identical assets or liabilities (Level 1 measurements) and the lowest priority to valuations based upon unobservable inputs that are significant to the valuation (Level 3 measurements). The guidance establishes three levels of the fair value hierarchy as follows:

 

Level 1 - Inputs that reflect unadjusted quoted prices in active markets for identical assets or liabilities that we have the ability to access at the measurement date;

 

Level 2 - Inputs other than quoted prices that are observable for the assets or liability either directly or indirectly, including inputs in markets that are not considered to be active;

 

Level 3 - Inputs that are unobservable.

 

Assets and liabilities measured at fair value are classified in their entirety based on the lowest level of input that is significant to the fair value measurement. Our assessment of the significance of a particular input to the fair value measurement in its entirety requires management to make judgments and consider factors specific to the asset or liability.

 

We recognize transfers between levels of the fair value hierarchy as of the end of the reporting period. There were no transfers within the hierarchy during the three months ended September 30, 2019.

 

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A summary of the assets and liabilities carried at fair value in accordance with the hierarchy defined above is as follows :

 

    Fair Value Measurements Using 
    Level 1    Level 2    Level 3    Total 
September 30, 2019                    
Assets:                    
Money market fund  $1,791,630   $   $   $1,791,630 
Total assets  $1,791,630   $   $   $1,791,630 

 

We use a market approach for determining the fair value of all its Level 1 and Level 2 money market funds and marketable securities. To value our money market funds, we value the funds at $1 stable net asset value, which is the market pricing convention for identical assets that we have the ability to access.

 

The investments are classified as available-for-sale debt securities. At September 30, 2019, the balance in our accumulated other comprehensive income comprised primarily of temporary unrealized gains related to our available-for-sale debt securities. There were no realized gains or losses recognized on the sale or maturity of available-for-sale debt securities for the nine months ended September 30, 2019 and as a result, we did not reclassify any amounts out of accumulated other comprehensive loss for the period. We have no available-for-sale debt securities as of September 30, 2019.

 

Research and Development Costs

 

We expense the cost of research and development as incurred. Research and development expenses consist of costs incurred in performing research and development activities, including clinical study costs, contracted services, and other external costs. Nonrefundable advance payments for goods and services that will be used in future research and development activities are expensed when the activity is performed or when the goods have been received, rather than when payment is made, in accordance with ASC 730, Research and Development.

 

Accrued Expenses

 

As part of the process of preparing our financial statements, we are required to estimate our accrued expenses. This process involves reviewing quotations and contracts, identifying services that have been performed on our behalf and estimating the level of service performed and the associated cost incurred for the service when we have not yet been invoiced or otherwise notified of the actual cost. The majority of our service providers invoice us monthly in arrears for services performed or when contractual milestones are met. We make estimates of our accrued expenses as of each balance sheet date in our financial statements based on facts and circumstances known to us at that time. We periodically confirm the accuracy of our estimates with the service providers and make accrued expense adjustments if necessary. The significant estimates in our accrued research and development expenses include fees due to service providers.

 

Emerging Growth Company Status

 

The Jumpstart Our Business Startups Act of 2012 (“JOBS Act”) was enacted on April 5, 2012. Section 107 of the JOBS Act provides that an “emerging growth company” can take advantage of the extended transition period provided in Section 7(a)(2)(B) of the Securities Act of 1933, as amended (the “Securities Act”), for complying with new or revised accounting standards. In other words, an “emerging growth company” can delay the adoption of certain accounting standards until those standards would otherwise apply to private companies. We have elected to use the extended transition period for complying with new or revised accounting standards under Section 102(b)(1) of the JOBS Act. This election allows us to delay the adoption of new or revised accounting standards that have different effective dates for public and private companies until those standards apply to private companies. As a result of this election, our financial statements may not be comparable to companies that comply with public company effective dates.

 

As an “emerging growth company,” we are entitled to rely on certain of exemptions and reduced reporting requirements, including without limitation, (i) providing an auditor’s attestation report on our system of internal controls over financial reporting pursuant to Section 404(b) of the Sarbanes-Oxley Act and (ii) complying with any requirement that may be adopted by the PCAOB regarding mandatory audit firm rotation or a supplement to the auditor’s report providing additional information about the audit and the financial statements, known as the auditor discussion and analysis. We will remain an emerging growth company until the earlier of (i) the last day of the fiscal year (a) following the fifth anniversary of the date we completed our initial public offering, which was June 29, 2015, (b) in which we have total annual gross revenue of at least $1.07 billion, or (c) in which we are deemed to be a large accelerated filer, which means the market value of our common stock that is held by non-affiliates exceeded $700.0 million as of the prior June 30th, and (ii) the date on which we have issued more than $1.0 billion in non-convertible debt during the prior three-year period.

 

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Results of Operations

 

Comparison of the Three Months Ended September 30, 2019 and 2018

 

The following table summarizes our results of operations for the three months ended September 30, 2019 and 2018, together with the changes in those items in dollars and as a percentage:

 

  

For the Three Months Ended

September 30,

   Dollar   Percentage 
   2019   2018   Change   Change 
Statement of Operations Data:                
Operating costs and expenses                    
Research and development  $1,036,689   $3,459,681   $(2,422,992)   (70)%
Patent costs   20,867    59,068    (38,201)   (65)%
General and administrative   1,122,825    1,144,750    (21,925)   (2)%
Total operating costs and expenses   2,180,381    4,663,499    (2,483,118)   (53)%
                     
Operating loss   (2,180,381)   (4,663,499)   (2,483,118)   (53)%
                     
Other income:                    
Interest income   13,172    17,237    (4,065)   (24)%
Total other income   13,172    17,237    (4,065)   (24)%
Net Loss  $(2,167,209)  $(4,646,262)  $2,479,053    (53)%

 

Research and Development Expenses

 

Research and development expenses decreased by approximately $2.4 million, or 70%, during the three months ended September 30, 2019 as compared to the three months ended September 30, 2018. The primary reason for this decrease is the completion of our Liberatus clinical trial at the beginning of the current period and our decision to suspend development activities of RP-G28 following the announcement of our Phase 3 clinical trial results in early September 2019, as we continue to analyze the results from the trial to better understand the data and clinical outcomes to assess a path forward for RP-G28. Research and development expenses during the three months ended September 30, 2018 primarily reflect the costs associated with initiation of the Liberatus clinical trial including manufacturing and payments made to the CRO.

 

Patent Costs

 

Patent costs were approximately $21,000 and $59,000 for the three months ended September 30, 2019 and 2018, respectively, representing a decrease of approximately $38,000, or 65%. The primary reason for the decrease is the timing of expenses related to the maintenance of patent rights, the prosecution of patents, the application for the issuance of patents, as well as the preparation to file national Phase applications in certain foreign countries.

 

General and Administrative Expenses

 

General and administrative expenses decreased slightly by approximately $22,000, or 2%, during the three months ended September 30, 2019 as compared to the three months ended September 30, 2018. Approximately $95,000 in stock-based expense was recognized during the three months ended September 30, 2019 as compared to approximately $171,000 during the same period in 2018.

 

Other Income

 

Other income decreased by approximately $4,000, or 24%, during the three months ended September 30, 2019 as compared to the three months ended September 30, 2018, primarily due to the lower balance in our higher-yielding short-term marketable debt securities in the three months ended September 30, 2019 as compared to the comparative period ended September 30, 2018.

 

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Comparison of the Nine Months Ended September 30, 2019 and 2018

 

The following table summarizes our results of operations for the nine months ended September 30, 2019 and 2018, together with the changes in those items in dollars and as a percentage:

 

  

For the Nine Months Ended

September 30,

   Dollar   Percentage 
   2019   2018   Change   Change 
Statement of Operations Data:                
Operating costs and expenses                    
Research and development  $6,044,580   $6,180,607   $(136,027)   (2)%
Patent costs   139,436    170,418    (30,982)   (18)%
General and administrative   3,621,888    3,957,545    (335,657)   (8)%
Total operating costs and expenses   9,805,904    10,308,570    (502,666)   5%
                     
Operating loss   (9,805,904)   (10,308,570)   502,666    5%
                     
Other income:                    
Interest income   117,777    64,965    52,812    81%
Total other income   117,777    64,965    52,812    81%
Net Loss  $(9,688,127)  $(10,243,605)  $555,478    (5)%

 

Research and Development Expenses

 

Research and development expenses decreased slightly by approximately $0.1 million, or 2%, during the nine months ended September 30, 2019 as compared to the nine months ended September 30, 2018. Research and development expenses during the nine months ended September 30, 2019 reflect expenses incurred in connection with the completion and close-out activities of our Liberatus clinical trial. Research and development expenses during the nine months ended September 30, 2018 primarily reflect extension study costs and expenses related to the preparation for and the initiation of the Liberatus clinical trial.

 

Patent Costs

 

Patent costs were approximately $139,000 and $170,000 for the nine months ended September 30, 2019 and 2018, respectively, representing a decrease of approximately $31,000, or 18%. The primary reason for the decrease is the timing of expenses related to the maintenance of patent rights, the prosecution of patents, the application for the issuance of patents, as well as the preparation to file national Phase applications in certain foreign countries.

 

General and Administrative Expenses

 

General and administrative expenses decreased by approximately $0.3 million, or 8%, during the nine months ended September 30, 2019 as compared to the nine months ended September 30, 2018, primarily due to decreases of approximately $0.2 million in stock-based compensation expense, approximately $0.1 million in recruitment fees and approximately $0.1 million in business development expenses, partially offset by an increase of approximately $0.1 million in taxes. Approximately $364,000 in stock-based compensation expense was recognized during the nine months ended September 30, 2019 as compared to approximately $562,000 during the same period in 2018.

 

Other Income

 

Other income increased by approximately $53,000, or 81%, during the nine months ended September 30, 2019 as compared to the nine months ended September 30, 2018, primarily due to our investing in higher-yielding short-term marketable debt securities in the nine months ended September 30, 2019 as compared to the nine months ended September 30, 2018.

 

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Liquidity and Capital Resources

 

Since our inception, we have incurred net losses and negative cash flows from operations and, as of September 30, 2019, we had an accumulated deficit of approximately $79.9 million. Substantially all of our net losses have resulted from costs incurred in connection with our research and development program, stock-based compensation, and from general and administrative costs associated with our operations.

 

At September 30, 2019, we had net working capital of approximately $0.1 million, and cash and cash equivalents of approximately $2.0 million.

 

Cash Flows

 

The following table sets forth the significant sources and uses of cash for the periods set forth below:

 

   For the Nine Months Ended
September 30,
 
   2019   2018 
Net cash provided by (used in):          
Operating activities  $(12,851,824)  $(10,130,131)
Investing activities   6,996,960    (2,008)
Financing activities       (3,256)
Net decrease in cash and cash equivalents  $(5,854,864)  $(10,135,395)

 

Operating Activities

 

During the nine months ended September 30, 2019, net cash used in operating activities of approximately $12.9 million primarily reflects our net loss for the period of approximately $9.7 million and changes in our working capital accounts of approximately $3.6 million, offset by changes in the noncash component of approximately $0.4 million. Changes in working capital accounts include decreases in accounts payable of approximately $1.9 million, accrued expenses of approximately $1.3 million and prepaid expenses of approximately $0.3 million.

 

Investing Activities

 

Net cash provided by investing activities for the nine months ended September 30, 2019 was from the sale of investments in marketable securities to finance the Liberatus clinical trial of RP-G28. Net cash used in investing activities of approximately $1,600 and $2,000 during the nine months ended September 30, 2019 and 2018, respectively, related to the purchase of office furniture and equipment.

 

Financing Activities

 

No cash was provided by financing activities for the nine months ended September 30, 2019 and 2018. Net cash used in financing activities related to payout of fractional shares for the nine months ended September 30, 2018.

 

Sources of Liquidity

 

Aspire Capital Common Stock Purchase Agreement

 

On May 4, 2017, we entered into a common stock purchase agreement with Aspire Capital Fund, LLC (“Aspire Capital”), which was amended and restated on March 29, 2019 and on July 23, 2019 (as amended and restated, the “Aspire Purchase Agreement”). The Aspire Purchase Agreement was amended and restated to adjust certain provisions to improve our access to funding under the agreement and to provide for the registration of the shares of our common stock to be sold in the future to Aspire Capital under the Purchase Agreement on a dedicated registration statement on Form S-1 instead of our shelf registration statement on Form S-3. The Aspire Purchase Agreement provides access to us of up to an aggregate of $6.5 million in proceeds through the sale of shares of our common stock through March 31, 2021.

 

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Under the Aspire Purchase Agreement, as amended, on any trading day we select, we have the right, in our sole discretion, to present Aspire Capital with a purchase notice (each, a “Purchase Notice”), directing Aspire Capital (as principal) to purchase up to 100,000 shares of our common stock per trading day, up to an aggregate of $6,500,000 of our common stock, at a per share price (the “Purchase Price”) equal to the lesser of: (i) the lowest sale price of our common stock on the sale date, or (ii) the arithmetic average of the three lowest closing sale prices for our common stock during the ten (10) consecutive trading days ending on the trading day immediately preceding the sale date. The aggregate purchase price payable by Aspire Capital on any one purchase date cannot exceed $500,000. In addition, on any date on which we submit a Purchase Notice to Aspire Capital in an amount of at least 100,000 shares and our stock price is not less than $0.25 per share, we can also, in our sole discretion, present Aspire Capital with a volume-weighted average price purchase notice (each, a “VWAP Purchase Notice”) directing Aspire Capital to purchase an amount of our common stock equal to up to 30% of the aggregate shares of our common stock traded on its principal market on the next trading day (the “VWAP Purchase Date”), as determined by us. Under the terms of the Aspire Purchase Agreement, the number of shares that can be sold pursuant to Aspire Capital is limited to 1,807,562 (the “Exchange Cap”), which represented 19.99% of our outstanding shares of common stock as of March 29, 2019, the date the agreement was first amended and restated, unless stockholder approval or an exception pursuant to the rules of the Nasdaq Capital Market was obtained to issue more than 19.99%. This limitation would not apply if, at any time the Exchange Cap was reached and at all times thereafter, the average price paid for all shares issued under the Aspire Purchase Agreement was equal to or greater than $0.86 (the “Minimum Price”), which was the closing price of our common stock immediately preceding the signing of the first amendment to the agreement. As of September 30, 2019, no shares of common stock have been sold or issued to Aspire Capital under the Aspire Purchase Agreement.

 

November 2018 Private Placement Financing

 

On November 5, 2018, we closed a PIPE financing with certain institutional investors, a key vendor and a member of our board of directors. Net proceeds from the PIPE financing were approximately $5.5 million, after deducting placement agent fees and other offering expenses. The securities sold by us consisted of 6,000 shares of a newly designated class of our Series B convertible preferred stock, with a stated value of $1,000 per share and an initial conversion price per share of $1.30 (subject to customary adjustment for stock dividends and stock splits) and warrants to purchase an aggregate of 2,307,685 shares of our common stock. Each investor received a warrant to purchase a number of shares of common stock equal to one half the number of shares of common stock into which their Series B convertible preferred stock is initially convertible. The warrants are exercisable immediately for a five-year period and have an exercise price of $1.30 per share (subject to customary adjustment for stock dividends and stock splits but without the down-round protective provisions of previously issued warrants). The proceeds received in the PIPE financing were allocated to each instrument on a relative fair value basis. Total proceeds of $6.0 million were allocated as follows: $1.4 million to warrants issued and $4.6 million to Series B convertible preferred stock.

 

Certain investors in the PIPE financing who at the time of closing of the PIPE financing owned shares of our Series A convertible preferred stock, exchanged, on a 1 for 1 share basis, their shares of Series A convertible preferred stock for shares of our newly designated class of Series C convertible preferred stock, with a stated value of $1,000 per share and convertible into shares of our common stock at an initial conversion price per share of $1.64 (subject to customary adjustment for stock dividends and stock splits).

 

At-the-Market Offering Agreement

 

On November 6, 2019, we entered into a Sales Agreement (the “ATM Agreement”) with A.G.P., pursuant to which we may offer and sell, from time to time through A.G.P., shares of our common stock having an aggregate offering price of up to $3,673,159 (the “Placement Shares”), subject to the terms and conditions of the ATM Agreement. Unless earlier terminated pursuant to the terms of the ATM Agreement, the ATM Agreement will automatically terminate upon the earlier to occur of (i) issuance and sale of all of the Placement Shares to or through A.G.P. and (ii) August 1, 2022.

 

Future Funding Requirements

 

To date, we have not generated any revenue. We do not know when, or if, we will generate any revenue from product sales. We do not expect to generate significant revenue from product sales unless and until we obtain regulatory approval of and commercialize RP-G28 or some other product candidate.

 

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Our operating expenses have decreased significantly since the completion of our Phase 3 clinical trial of RP-G28 and we have made additional operating expense reductions following the announcement of the trial results, including reductions to executive and board compensation. We will continue to make further reductions as necessary.

 

Based upon our current operating plan, we believe that our existing cash and cash equivalents, together with interest and any proceeds received under the Aspire Purchase Agreement and/or ATM Agreement, will enable us to fund our operating expenses and capital expenditure requirements through the first quarter of 2020.

 

However, we will need substantial additional funding to continue our operations, particularly if we resume development activities for RP-G28 or some other product candidate. In addition, we expect that we will need additional funding to pursue any strategic transaction.

 

To the extent that we raise additional capital through the sale of equity or convertible debt securities, the ownership interests of our common stockholders will be diluted, and the terms of these securities may include liquidation or other preferences that adversely affect the rights of our common stockholders. Debt financing, if available, may involve agreements that include covenants limiting or restricting our ability to take specific actions, such as incurring additional debt, making capital expenditures or declaring dividends. If we raise additional funds through government or other third-party funding, commercialization, marketing and distribution arrangements or other collaborations, strategic alliances or licensing arrangements with third parties, we may have to relinquish valuable rights to our technologies, future revenue streams, research programs or product candidates or to grant licenses on terms that may not be favorable to us.

 

Contractual Obligations and Commitments

 

There have been no material changes to our contractual obligations and commitments from those disclosed in our 2018 Annual Report, except that, as disclosed in a Current Report on Form 8-K filed on October 15, 2019, we entered into amendments to the respective employment offer letters of Andrew J. Ritter, our Chief Executive Officer, John W. Beck, our Chief Financial Officer, and Ira E. Ritter, our Chief Strategic Officer (the “Offer Letter Amendments”) on October 15, 2019. Pursuant to the terms of the Offer Letter Amendments, each of our executive officers agreed to defer a portion of his annual base salary (the “Deferred Amounts”), as set forth below, until such time as the board of directors, in its sole discretion, decides to pay the Deferred Amounts (or any portion of the Deferred Amounts) to the executive officers, if ever.

 

Name of Executive Officer  Deferred Amount 
Andrew J. Ritter  $70,200 
John W. Beck  $33,000 
Ira E. Ritter  $53,820 

 

Off-Balance Sheet Arrangements

 

Through September 30, 2019, we do not have any off-balance sheet arrangements, as defined by applicable SEC regulations.

 

ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

 

As a “smaller reporting company” as defined by Item 10 of Regulation S-K, we are not required to provide the information required by Item 3.

 

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ITEM 4. CONTROLS AND PROCEDURES

 

Evaluation of Disclosure Controls and Procedures

 

Our management, with the participation of our principal executive officer and principal financial officer, evaluated the effectiveness of our disclosure controls and procedures as of September 30, 2019, the end of the period covered by this Quarterly Report.

 

Based on this evaluation, our principal executive officer and principal financial officer have concluded that our disclosure controls and procedures as of September 30, 2019 were effective to provide reasonable assurance that the information required to be disclosed by us in reports filed under the Securities Exchange Act of 1934, as amended, is recorded, processed, summarized and reported within the time periods specified in the SEC’s rules and forms, and that such information is accumulated and communicated to our management, including our principal executive officer and principal financial officer, as appropriate, to allow timely decisions regarding required disclosure. We believe that a controls system, no matter how well designed and operated, cannot provide absolute assurance that the objectives of the controls system are met, and no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within a company have been detected.

 

Changes in Internal Control over Financial Reporting

 

There were no changes in our internal control over financial reporting that occurred during the fiscal quarter ended September 30, 2019 that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

 

PART II - OTHER INFORMATION

 

ITEM 1. LEGAL PROCEEDINGS

 

The Company is not currently involved in any legal matters arising in the normal course of business. From time to time, the Company could become involved in disputes and various litigation matters that arise in the normal course of business. These may include disputes and lawsuits related to intellectual property, licensing, contract law and employee relations matters.

 

ITEM 1A. RISK FACTORS

 

The risks described in Item 1A. Risk Factors of our 2018 Annual Report could materially and adversely affect our business, financial condition and results of operations. The risk factors discussed in our 2018 Annual Report do not identify all risks that we face because our business operations could also be affected by additional factors that are not presently known to us or that we currently consider to be immaterial to our operations. Except as set forth below, there are no material changes to the risk factors set forth in our 2018 Annual Report. Investors should consider the risk factors described in our 2018 Annual Report and set forth below prior to making an investment decision with respect to our stock.

 

We cannot be certain that RP-G28 will receive regulatory approval, and without regulatory approval we will not be able to market RP-G28.

 

The development of a product candidate and issues relating to its approval and marketing are subject to extensive regulation by the Food and Drug Administration (“FDA”) in the United States, the European Medicines Agency (“EMA”) in Europe, and regulatory authorities in other countries, with regulations differing from country to country. We are not permitted to market our product candidates in the United States or Europe until we receive approval of a New Drug Application (“NDA”) from the FDA or a Marketing Authorization Application (“MAA”) from the EMA, respectively. We have not submitted any marketing applications for RP-G28.

 

We completed enrollment in our Phase 3 clinical trial known as “Liberatus” in March 2019 and last patient las visit in July 2019. In September 2019, we announced that our Phase 3 clinical trial of RP-G28 for LI failed to demonstrate statistical significance in its pre-specified primary and secondary endpoints. While the Company is continuing to analyze the results of the trial to better understand the data and clinical outcomes to assess a path forward for RP-G28, no further development efforts of RP-G28 are currently ongoing.

 

We may be required to conduct additional clinical trials of RP-G28 if we decide to continue its clinical development. We cannot predict whether future trials and studies will be successful or whether regulators will agree with our conclusions regarding the preclinical studies and clinical trials we have conducted to date and/or any we may conduct in the future.

 

If we are unable to obtain approval from the FDA, the EMA or other regulatory agencies for RP-G28, we will not be able to market RP-G28. If we are unable to market RP-G28, we may not be able to ever become profitable.

 

Our failure to meet the continued listing requirements of Nasdaq could result in a de-listing of our common stock.

 

If we fail to satisfy the continued listing requirements of Nasdaq, Nasdaq may take steps to de-list our common stock. Such a de-listing would likely have a negative effect on the price of our common stock and would impair your ability to sell or purchase our common stock when you wish to do so. In the event of a de-listing, we would take actions to restore our compliance with Nasdaq’s listing requirements, but we can provide no assurance that any such action taken by us would allow our common stock to become listed again, stabilize the market price or improve the liquidity of our common stock, prevent our common stock from dropping below the Nasdaq minimum bid price requirement or prevent future non-compliance with Nasdaq’s listing requirements.

 

26

 

 

On August 19, 2019, we received a written notice (the “Stockholders’ Equity Notice”) from Nasdaq indicating that we were not in compliance with Nasdaq Listing Rule 5550(b)(1) (“Rule 5550(b)(1)”) as our stockholders’ equity, as reported in our Quarterly Report on Form 10-Q for the period ended June 30, 2019, was below $2.5 million, which is the minimum stockholders’ equity required for compliance with Rule 5550(b)(1). Further, as of August 19, 2019, the Company did not satisfy the conditions for the alternative market value of listed securities standard for continued listing or the net income standard for continued listing. The Stockholders’ Equity Notice has no immediate effect on the listing of our common stock on The Nasdaq Capital Market. As required by the Stockholders’ Equity Notice, we submitted a plan to regain compliance to Nasdaq. If Nasdaq accepts our plan, Nasdaq may grant us an extension of up to 180 calendar days from the date of the Stockholders’ Equity Notice, or until February 15, 2020, to demonstrate compliance. If Nasdaq does not accept our plan to regain compliance, we will have the right to appeal such decision to a Nasdaq hearings panel.

 

On October 28, 2019, we received a second written notice (the “Bid Price Notice”) from Nasdaq notifying us that, because the closing bid price for our common stock had been below $1.00 per share for 30 consecutive business days, we no longer comply with the minimum bid price requirement for continued listing on The Nasdaq Capital Market. Nasdaq Listing Rule 5550(a)(2) requires listed securities to maintain a minimum bid price of $1.00 per share (the “Minimum Bid Price Requirement”), and Listing Rule 5810(c)(3)(A) provides that a failure to meet the Minimum Bid Price Requirement exists if the deficiency continues for a period of 30 consecutive business days. The Bid Price Notice has no immediate effect on the listing of our common stock on The Nasdaq Capital Market. Pursuant to Nasdaq Marketplace Rule 5810(c)(3)(A), we have been provided an initial compliance period of 180 calendar days, or until April 27, 2020, to regain compliance with the Minimum Bid Price Requirement. During the compliance period, our shares of common stock will continue to be listed and traded on The Nasdaq Capital Market. To regain compliance, the closing bid price of our common stock must meet or exceed $1.00 per share for a minimum of 10 consecutive business days during the 180-calendar day grace period. In the event we are not in compliance with the Minimum Bid Price Requirement by April 27, 2020, we may be afforded a second 180 calendar day grace period. To qualify, we would be required to meet the continued listing requirements for market value of publicly held shares and all other initial listing standards for The Nasdaq Capital Market, with the exception of the Minimum Bid Price Requirement. In addition, we would be required to provide written notice of our intention to cure the minimum bid price deficiency during this second 180-day compliance period by effecting a reverse stock split, if necessary. We intend to actively monitor the bid price of our common stock between now and April 27, 2020 and will consider available options to regain compliance with the Minimum Bid Price Requirement.

 

We are not in good standing in the State of Delaware, the state of our incorporation, as a result of outstanding franchise taxes.

 

We are currently not in good standing with the State of Delaware, the state of our incorporation, due to outstanding corporate franchise taxes owed to the State of Delaware for fiscal year 2019. We have been assessed approximately $120,000 in franchise taxes due to the State of Delaware. Our loss of good standing with the State of Delaware could have negative consequences for us and our business including: (i) possible loss of access to the courts; (ii) difficulties in securing capital and financing from lenders; (iii) tax liens being imposed on us; (iv) a loss of name rights; (v) administrative dissolution or revocation; and/or (vi) fines and penalties.

 

ITEM 2. UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS

 

Unregistered Sales of Equity Securities

 

None

 

Purchases of Equity Securities by the Issuer and Affiliated Purchasers

 

None

 

ITEM 5. OTHER INFORMATION

 

On November 12, 2019, we entered into an irrevocable consent and waiver agreement (the “Waiver Agreement”) with the holders of our outstanding Series B convertible preferred stock (the “Series B Holders”), who are also parties to that certain Securities Purchase Agreement, dated as of October 30, 2018 (the “2018 Purchaser Agreement”), by and among the Company and the purchasers identified therein (including the Series B Holders). Pursuant to the terms of the Waiver Agreement, the Series B Holders agreed to waive the restriction in Section 4.12(b) of the 2018 Purchase Agreement prohibiting Dilutive Issuances (as defined in the 2018 Purchase Agreement) for the remainder of the Restricted Period (as defined in the 2018 Purchase Agreement), such that Section 4.12(b) of the 2018 Purchase Agreement is of no further force and effect (the “Waiver”). In exchange for the Series B Holders’ Waiver and subject to the other terms and conditions described in the Waiver Agreement, we agreed to reduce the conversion price of the Series B convertible preferred stock from $1.30 to $0.20 per share and to reduce the conversion price of the Series C convertible preferred stock from $1.64 to $0.20 per share, in each case subject to the approval of our stockholders to issue the additional shares of common stock that will be issuable upon conversion of the Series B convertible preferred stock and Series C convertible preferred stock as a result of the Series B Conversion Price Adjustment and the Series C Conversion Price Adjustment as required by the applicable Nasdaq rules, which stockholder approval we agreed to seek by no later than the earlier of (i) our next annual or special meeting of stockholders, or (ii) February 14, 2020.

 

The foregoing description of the Waiver Agreement is not complete and is qualified in its entirety by reference to the full text of the form of Waiver Agreement, a copy of which is filed herewith as Exhibit 10.5 and is incorporated herein by reference.

 

27

 

 

ITEM 6. EXHIBITS

 

        Incorporated by Reference
Exhibit
No.
  Description   Form   File No.   Exhibit  

Filing

Date

                     
10.1   Offer Letter Amendment by and between Ritter Pharmaceuticals, Inc. and Andrew J. Ritter, dated October 15, 2019.   8-K   001-37428   10.1   10/15/2019
                     
10.2   Offer Letter Amendment by and between Ritter Pharmaceuticals, Inc. and John W. Beck, dated October 15, 2019.   8-K   001-37428   10.2   10/15/2019
             
10.3   Offer Letter Amendment by and between Ritter Pharmaceuticals, Inc. and Ira E. Ritter, dated October 15, 2019.   8-K   001-37428   10.3   10/15/2019
                     
10.4   Sales Agreement, dated November 6, 2019 between Ritter Pharmaceuticals, Inc. and A.G.P./Alliance Global Partners   8-K   001-37428   10.1   11/7/2019
                     

10.5

 

Form of Consent and Waiver with Series B Convertible Preferred Stockholders

               
                     
31.1   Certificate of principal executive officer pursuant to Rule 13a-14(a)/15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.        
                     
31.2   Certificate of principal financial officer pursuant to Rule 13a-14(a)/15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.                
                     
32.1   Certificate of principal executive officer and principal financial officer pursuant to 18 U.S.C. § 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.                
                     
101.INS#   XBRL Instance Document.                
                     
101.SCH#   XBRL Taxonomy Extension Schema Document.                
                     
101.CAL#   XBRL Taxonomy Extension Calculation Linkbase Document.                
                     
101.DEF#   XBRL Taxonomy Extension Definition Linkbase Document.                
                     
101.LAB#   XBRL Taxonomy Extension Label Linkbase Document.                
                     
101.PRE#   XBRL Taxonomy Extension Presentation Linkbase Document.                

 

# XBRL (Extensible Business Reporting Language) information is furnished and not filed herewith, is not a part of a registration statement or Prospectus for purposes of sections 11 or 12 of the Securities Act of 1933, is deemed not filed for purposes of section 18 of the Securities Exchange Act of 1934, and otherwise is not subject to liability under these sections.

 

28

 

 

SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

 

November 14, 2019 RITTER PHARMACEUTICALS, INC.
     
  By: /s/ Andrew J. Ritter
  Name: Andrew J. Ritter
  Title: Chief Executive Officer

 

29

 

 

EX-10.5 2 ex10-5.htm

 

Exhibit 10.5

 

 

November 11, 2019

 

[NAME]

[ADDRESS]

[ADDRESS]

 

  Re: Irrevocable Consent and Waiver of Restriction on Dilutive Issuances

 

Dear [NAME]:

 

This irrevocable consent and waiver letter (this “Consent and Waiver”) relates to certain restrictions contained in that certain Securities Purchase Agreement (the “Agreement”), dated as of October 30, 2018, by and between Ritter Pharmaceuticals, Inc. (the “Company”) and the purchasers identified therein, including the undersigned. All capitalized terms used but not otherwise defined herein shall have the meanings given to them in the Agreement.

 

Section 4.12(b) of the Agreement prohibits the Company from (A) effecting or entering into an agreement to effect any issuance by the Company or any of its Subsidiaries of Common Stock or Common Stock Equivalents (or a combination of units thereof) involving a Variable Rate Transaction, and (B) selling or granting any option to purchase, or selling or granting any right to reprice, or otherwise disposing of or issuing (or announcing any offer, sale grant or any option to purchase or other disposition of) any Common Stock or Common Stock Equivalents, at an effective price per share less than $1.64 (subject to adjustment as provided in the Agreement) ((A) and (B) collectively referred to as the “Dilutive Issuance Restriction”), without the consent of the Required Holders.

 

The Company desires to engage in one or more financings during the remainder of the Restricted Period in order to, among other things, regain its compliance with Nasdaq’s stockholders’ equity requirement for continued listing on the Nasdaq Capital Market, as set forth in Nasdaq Rule 5550(b)(1).

 

Upon the terms and conditions described herein, the undersigned hereby consents to waive the Dilutive Issuance Restriction set forth in Section 4.12(b) of the Agreement in its entirety for the remainder of the Restricted Period (such that Section 4.12(b) of the Agreement shall be of no further force and effect) in exchange for the Company’s agreement to reduce the Conversion Price of the Series B Convertible Preferred Stock (the “Series B Preferred Stock”) from $1.30 to $0.20 (the “Series B Conversion Price Adjustment”) and to reduce the Conversion Price of the Series C Convertible Preferred Stock (the “Series C Preferred Stock”) from $1.64 to $0.20 (the “Series C Conversion Price Adjustment”), in each case subject to the approval of the Company’s stockholders to issue the additional shares of Common Stock that will be issuable upon conversion of the Series B Preferred Stock and Series C Preferred Stock as a result of the Series B Conversion Price Adjustment and the Series C Conversion Price Adjustment as required by applicable Nasdaq rules (the “Required Stockholder Approval”).

 

Provided the Stockholder Approval has been obtained prior to or contemporaneously with (i) the approval of the Company’s stockholders of a Fundamental Transaction, if required, and (ii) prior to the consummation of a Fundamental Transaction, the undersigned agrees that if at any time while the Series B Preferred Stock and/or Series C Preferred Stock is outstanding, the Company consummates a Fundamental Transaction, then, immediately prior to but subject to the occurrence of the Fundamental Transaction, and subject to the “Beneficial Ownership Limitation” set forth in each of the Series B Certificate of Designation and Series C Certificate of Designation, each outstanding share of Preferred B Preferred Stock and Series C Preferred Stock shall automatically convert into shares of Common Stock (the “Automatic Conversion Requirement”), without any action of or by the holders of the Series B Preferred Stock and Series C Preferred Stock, at the conversion price then in effect, and the holders of Series B Preferred Stock and Series C Preferred Stock shall receive, for each share of Common Stock received upon conversion (the “Conversion Shares”), such consideration, at the same time and subject to the same terms and conditions, as the other holders of Common Stock pursuant to the terms of the Fundamental Transaction. In the event the Automatic Conversion Requirement is unable to be effected due to the Beneficial Ownership Limitation, then the Automatic Conversion Requirement will be held in abeyance, in whole or in part, until such time or times as it may be accomplished, subject to the Beneficial Ownership Limitation.

 

   

 

 

Section 5.5 of the Agreement provides that any provision of the Agreement may be waived, modified, supplemented or amended by a written instrument signed by the Company and the holders of at least 60% of the then outstanding shares of Series B Preferred Stock (the “Required Holders”). Section 4 of the Series B Certificate of Designation provides that the Series B Certificate of Designation may be altered or amended with the affirmative vote of the Required Holders. Section 4 of the Series C Certificate of Designation provides that the Series C Certificate of Designation may be altered or amended with the affirmative vote of 60% of the then outstanding shares of Series C Preferred Stock.

 

Subject to the Company’s receipt of approval from the Required Holders to waive the Dilutive Issuance Restriction and amend the Series B Certificate of Designation and Series C Certificate of Designation, the Company agrees to:

 

(1) seek the Required Stockholder Approval by no later than the earlier of (i) the date of the Company’s next annual or special meeting of stockholders, or (ii) February 14, 2020;

 

(2) subject to the receipt of the Required Stockholder Approval, prepare and file a Certificate of Amendment to the Series B Certificate of Designation (the “Series B Certificate of Amendment”) reflecting the Series B Conversion Price Adjustment and the Automatic Conversion Requirement within ten (10) days of the date of receiving the Required Stockholder Approval;

 

(3) subject to the receipt of the Required Stockholder Approval, prepare and file a Certificate of Amendment to the Series C Certificate of Designation (the “Series C Certificate of Amendment”) reflecting the Series C Conversion Price Adjustment and the Automatic Conversion Requirement within ten (10) days of the date of receiving the Required Stockholder Approval; and

 

(4) subject to the receipt of the Required Stockholder Approval, file a post-effective amendment (the “Post-Effective Amendment”) to the Company’s registration statement on Form S-3 (File No. 333-228501) within fifteen (15) days of the date of receiving the Required Stockholder Approval in order to register for resale by the holders of the Series B Preferred Stock and Series C Preferred Stock, the additional number of shares of Common Stock that will be issuable to them upon conversion of the shares of Series B Preferred Stock following the Series B Conversion Price Adjustment and the shares of Series C Preferred Stock following the Series C Conversion Price Adjustment.

 

Not less than two (2) business days prior to the filing of each of the Series B Certificate of Amendment, the Series C Certificate of Amendment and the Post-Effective Amendment, the Company shall furnish to the holders of the Series B Preferred Stock and Series C Preferred Stock (collectively, the “Holders”), including the undersigned, copies of the documents to be filed, which documents will be subject to the review of the Holders. The Company shall not file the Series B Certificate of Amendment, the Series C Certificate of Amendment and/or the Post-Effective Amendment without the consent of the required Holders (which consent shall not be unreasonably withheld).

 

For purposes of this Consent and Waiver, the undersigned hereby represents and warrants to the Company that the undersigned is the record and beneficial owner of ________ shares of Series B Preferred Stock and that the undersigned has the power and authority to enter into this Consent and Waiver.

 

This Consent and Waiver is not intended to waive or modify the undersigned’s rights, including the right at all times to convert the Series B Preferred Stock and/or Series C Preferred Stock at the Conversion Price applicable at the time of such conversion, nor obligations under the Agreement, the Series B Certificate of Designation or the Series C Certificate of Designation other than as stated herein. Except as expressly stated herein, all terms and conditions of the Agreement, the Series B Certificate of Designation and the Series C Certificate of Designation shall be as set forth therein.

 

This Consent and Waiver shall be subject to the same Miscellaneous provisions of Section 8 of each of the Certificate of Designations of Preferences, Rights and Limitations of Series B Convertible Preferred Stock and the Certificate of Designations of Preferences, Rights and Limitations of Series C Convertible Preferred Stock.

 

This Consent and Waiver may be executed in counterparts, each of which shall be deemed an original, but all of which together shall be deemed to be one and the same agreement. A signed copy of this Consent and Waiver delivered by facsimile, e-mail, or other means of electronic transmission shall be deemed to have the same legal effect as delivery of an original signed copy of this letter agreement.

 

[Signature Page Follows]

 

   

 

 

  Very Truly Yours,
   
  RITTER PHARMACEUTICALS, INC.
     
  By:                                    
  Name: Andrew Ritter
  Title: Chief Executive Officer
   
  AGREED AND ACCEPTED:
   
   
  [NAME]

 

   

 

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Exhibit 31.1

 

CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER PURSUANT TO

SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

 

I, Andrew J. Ritter, certify that:

 

1. I have reviewed this quarterly report on Form 10-Q of Ritter Pharmaceuticals, Inc., a Delaware corporation;

 

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

 

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

 

4. The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

 

a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant is made known to us by others within those entities, particularly during the period in which this report is being prepared;

 

b) Designed such control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes with generally accepted accounting principles;

 

c) Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

 

d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

 

5. The registrant’s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

 

a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

 

b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

 

November 14, 2019 By: /s/ Andrew J. Ritter
  Name: Andrew J. Ritter
  Title: Chief Executive Officer

 

 
 

 

EX-31.2 5 ex31-2.htm

 

Exhibit 31.2

 

CERTIFICATION OF PRINCIPAL FINANCIAL OFFICER PURSUANT TO

SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

 

I, John W Beck, certify that:

 

1. I have reviewed this quarterly report on Form 10-Q of Ritter Pharmaceuticals, Inc., a Delaware corporation;

 

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

 

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

 

4. The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

 

a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant is made known to us by others within those entities, particularly during the period in which this report is being prepared;

 

b) Designed such control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes with generally accepted accounting principles;

 

c) Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

 

d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

 

5. The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

 

a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

 

b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

 

November 14, 2019 By: /s/ John W Beck
  Name: John W Beck
  Title: Chief Financial Officer (Principal Financial Officer)

 

 
 

 

 

EX-32.1 6 ex32-1.htm

 

Exhibit 32.1

 

CERTIFICATIONS PURSUANT TO 18 U.S.C. SECTION 1350 AS ADOPTED PURSUANT TO

SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

 

Each of the undersigned, Andrew J. Ritter, Chief Executive Officer of Ritter Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and John W. Beck, Chief Financial Officer of the Company, do hereby certify, pursuant to 18 U.S.C. Section 1350 as adopted pursuant to Section 906 of the Sarbanes- Oxley Act of 2002, that, to his knowledge (1) the quarterly report on Form 10-Q of the Company for the nine months ended September 30, 2019, as filed with the Securities and Exchange Commission on the date hereof (the “Report”), fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended, and (2) the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

 

November 14, 2019

 

  By: /s/ Andrew J. Ritter
  Name: Andrew J. Ritter
  Title: Chief Executive Officer (Principal Executive Officer)

 

November 14, 2019

 

  By: /s/ John W Beck
  Name: John W Beck
  Title: Chief Financial Officer (Principal Financial Officer)

 

These certifications accompanying and being “furnished” with this Report, shall not be deemed “filed” by the Company for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to liability under that Section and shall not be deemed to be incorporated by reference into any filing of the Company under the Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended, whether made before or after the date of this Report, irrespective of any general incorporation language contained in such filing.

 

 
 

 

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PreferredStockSeriesAMember PreferredStockSeriesBMember PreferredStockSeriesCMember Assets, Current Other Assets, Noncurrent Other Assets Assets Liabilities, Current Liabilities Stockholders' Equity Attributable to Parent Liabilities and Equity Operating Expenses Operating Income (Loss) Nonoperating Income (Expense) Comprehensive Income (Loss), Net of Tax, Including Portion Attributable to Noncontrolling Interest Shares, Outstanding Marketable Securities, Unrealized Gain (Loss) Increase (Decrease) in Accrued Interest Receivable, Net Increase (Decrease) in Prepaid Expense Increase (Decrease) in Other Current Assets Increase (Decrease) in Accounts Payable Increase (Decrease) in Accrued Liabilities IncreaseDecreaseInLeaseLiabilities Increase (Decrease) in Other Current Liabilities Payments to Acquire Property, Plant, and Equipment Net Cash Provided by (Used in) Investing Activities Net Cash Provided by (Used in) Financing Activities Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations Lessee, Operating Lease, Liability, Payments, Due Lessee, Operating Lease, Liability, Undiscounted Excess Amount Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares Share-based Compensation Arrangement by Share-based Payment Award, Option, Nonvested, Weighted Average Exercise Price EX-101.PRE 12 rttr-20190930_pre.xml XBRL PRESENTATION FILE XML 13 report.css IDEA: XBRL DOCUMENT /* Updated 2009-11-04 */ /* v2.2.0.24 */ /* DefRef Styles */ ..report table.authRefData{ background-color: #def; 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Stock-Based Compensation - Schedule of Nonvested Restricted Stock Units (Details)
9 Months Ended
Sep. 30, 2019
$ / shares
shares
Share-based Payment Arrangement [Abstract]  
Number of Units Unvested, Beginning balance | shares 1,100,000
Number of Units Granted | shares 35,000
Number of Units Forfeited | shares
Number of Units Expired | shares (35,000)
Number of Units Unvested, Ending balance | shares 1,100,000
Weighted Average Grant Date Fair Value Unnvested, Beginning balance | $ / shares $ 2.73
Weighted Average Grant Date Fair Value Granted | $ / shares 0.63
Weighted Average Grant Date Fair Value Forfeited | $ / shares
Weighted Average Grant Date Fair Value Expired | $ / shares 0.63
Weighted Average Grant Date Fair Value Unvested, Ending balance | $ / shares $ 2.73
XML 16 R10.htm IDEA: XBRL DOCUMENT v3.19.3
Property and Equipment
9 Months Ended
Sep. 30, 2019
Property, Plant and Equipment [Abstract]  
Property and Equipment

NOTE 4 - PROPERTY AND EQUIPMENT

 

Property and equipment consists of the following:

 

    Estimated Life   September 30, 2019     December 31, 2018  
Computers and equipment   5 years   $ 17,178     $ 15,589  
Furniture and fixtures   7 years     19,158       19,158  
Total property and equipment         36,336       34,747  
Accumulated depreciation         (19,137 )     (14,587 )
Total property and equipment, net       $ 17,199     $ 20,160  

 

Depreciation expense of approximately $1,600 was recognized for the three months ended September 30, 2019 and approximately $1,500 was recognized for the three months ended September 30, 2018. Depreciation expense of approximately $4,600 was recognized for the nine months ended September 30, 2019 and approximately $4,300 was recognized for 2018. Depreciation expense is classified in general and administrative expense in the accompanying unaudited condensed statements of operations.

XML 17 R14.htm IDEA: XBRL DOCUMENT v3.19.3
Stock-Based Compensation
9 Months Ended
Sep. 30, 2019
Share-based Payment Arrangement [Abstract]  
Stock-Based Compensation

NOTE 8 - STOCK-BASED COMPENSATION

 

Equity Incentive Plans

 

The Company has issued equity awards pursuant to its 2015 Equity Incentive Plan (the “2015 Plan”), 2009 Stock Plan and 2008 Stock Plan (collectively the “Plans”). The Plans permit the Company to grant non-statutory stock options, incentive stock options and other equity awards to the Company’s employees, outside directors and consultants; however, incentive stock options may only be granted to the Company’s employees. Beginning June 29, 2015, no further awards may be granted under the 2008 Stock Plan or 2009 Stock Plan. However, to the extent awards under the 2008 Plan or 2009 Plan are forfeited or lapse unexercised or are settled in cash, the common stock subject to such awards will be available for future issuance under the 2015 Plan.

 

On June 2, 2017, the stockholders of the Company approved an amendment to the 2015 Plan at the 2017 annual meeting of stockholders, which among other things, increased the number of shares that may be issued pursuant to awards under the 2015 Plan by 83,800 shares of common stock.

 

On September 15, 2017, the stockholders of the Company approved an amendment to the 2015 Plan at a special meeting of stockholders, which among other things, increased the number of shares that may be issued pursuant to awards under the 2015 Plan by 2,585,871 shares of common stock. As of September 30, 2019, the aggregate number of shares of common stock authorized for issuance under the 2015 Plan, as amended, was 2,750,000 and 183,124 shares were available for issuance as of September 30, 2019.

 

The following represents a summary of the options granted to employees and non-employees that are outstanding at September 30, 2019 and changes during the period then ended:

 

    Options     Weighted Average Exercise Price     Aggregate Intrinsic Value     Weighted Average Remaining Contractual
Life (in years)
 
Outstanding at December 31, 2018     673,885     $ 19.82     $ ―        8.2  
Granted     698,750     $ 0.62     $ ―        9.0  
Exercised/ Expired/ Forfeited     (28,500 )   $ 0.98     $ ―        ―   
Outstanding at September 30, 2019     1,344,135     $ 10.24     $ ―        8.4  
Exercisable at September 30, 2019     531,528     $ 28.66     $ ―        7.4  

 

The exercise price for an option issued under the 2015 Plan is determined by the Board of Directors, but will be (i) in the case of an incentive stock option (A) granted to an employee who, at the time of grant of such option, is a 10% stockholder, no less than 110% of the fair market value per share on the date of grant; or (B) granted to any other employee, no less than 100% of the fair market value per share on the date of grant; and (ii) in the case of a non-statutory stock option, no less than 100% of the fair market value per share on the date of grant. The options awarded under the Plans will vest as determined by the Board of Directors but will not exceed a ten-year period.

 

Fair Value of Equity Awards

 

The Company utilizes the Black-Scholes option pricing model to value awards under its Plans. Key valuation assumptions include:

 

Expected dividend yield. The expected dividend is assumed to be zero as the Company has never paid dividends and has no current plans to pay any dividends on the Company’s common stock.
   
Expected stock-price volatility. As the Company’s common stock only recently became publicly traded, the expected volatility is derived from the average historical volatilities of publicly traded companies within the Company’s industry that the Company considers to be comparable to the Company’s business over a period approximately equal to the expected term and the Company.

 

Risk-free interest rate. The risk-free interest rate is based on the U.S. Treasury yield in effect at the time of grant for zero coupon U.S. Treasury notes with maturities approximately equal to the expected term.
   
Expected term. The expected term represents the period that the stock-based awards are expected to be outstanding. The Company’s historical share option exercise experience does not provide a reasonable basis upon which to estimate an expected term because of a lack of sufficient data. Therefore, the Company estimates the expected term by using the simplified method provided by the SEC. The simplified method calculates the expected term as the average of the time-to-vesting and the contractual life of the options.

 

The material factors incorporated in the Black-Scholes model in estimating the fair value of the options granted for the periods presented were as follows (three months ended September 30, 2018 stock price adjusted for 1-for-10 reverse stock split):

 

    For the three months ended September 30,     For the nine months ended September 30,  
    2019     2018     2019     2018  
Expected dividend yield     0.00 %     0.00 %     0.00 %     0.00 %
Expected stock-price volatility     69.00% – 69.38 %     48.89% – 50.22 %     46.33% – 69.38 %     46.47% – 53.11 %
Risk-free interest rate     1.47% – 1.54 %     2.78% – 3.07 %     1.47% – 2.60 %     2.46% – 3.07 %
Expected average term of options     5 –7       7 – 10       5 – 7       5 – 10  
Stock price   $ 1.04     $ 1.85 – $2.22     $ 0.60 – $1.04     $ 1.85 – $3.40  

 

Restricted Stock Units

 

Certain employees and consultants have been awarded restricted stock units. The restricted stock units include either milestone or time-based vesting. The following table summarizes restricted stock unit activity for the nine months ended September 30, 2019:

 

    Number of
Units
   

Weighted Average

Grant Date

Fair Value

 
Unvested at December 31, 2018     1,100,000     $ 2.73  
Granted     35,000       0.63  
Forfeited            
Expired     (35,000 )     0.63  
Unvested at September 30, 2019     1,100,000     $ 2.73  

 

Stock-Based Compensation

 

The Company recognized stock-based compensation expense for services within general and administrative expense in the accompanying statements of operations of approximately $95,000 and $171,000 for the three months ended September 30, 2019 and 2018, respectively, and $364,000 and $562,000 for the nine months ended September 30, 2019 and 2018, respectively. As of September 30, 2019, there was approximately $334,000 of total unrecognized compensation cost related to unvested stock-based compensation arrangements. This cost is expected to be recognized over a weighted average period of 1.46 years.

 

No stock options were exercised during the nine months ended September 30, 2019.

XML 18 R18.htm IDEA: XBRL DOCUMENT v3.19.3
Summary of Significant Accounting Policies (Tables)
9 Months Ended
Sep. 30, 2019
Accounting Policies [Abstract]  
Schedule of Supplemental Cash Flow Information Related to Leases

Other information related to the Company’s leases is provided below.

 

    Nine Months Ended
September 30, 2019
 
Supplemental Cash Flows Information        
Cash paid for amounts included in the measurement of lease liability:        
Operating cash flows from operating lease     86,234  
Operating lease asset obtained in exchange for lease obligation:        
Operating lease   $ 198,319  
Remaining lease term        
Operating lease     1.1 years  
Discount rate        
Operating lease     6.00 %

Schedule of Future Minimum Lease Payments Under Non-cancelable Operating Leases

Future payments under non-cancelable extended operating leases having initial or remaining terms of one year or more are as follows for the remaining fiscal year and thereafter:

 

Future minimum lease payments year ending December 31,      
2019 (remaining)   $ 30,675  
2020     103,254  
Total future minimum lease payments, undiscounted     133,929  
Less imputed interest     (4,581 )
Present value of lease liabilities   $ 129,348  
         
Operating lease liabilities reported as of September 30, 2019:        
Operating lease liabilities-current   $ 119,074  
Operating lease liabilities-non-current     10,274  
Total   $ 129,348  

XML 19 R22.htm IDEA: XBRL DOCUMENT v3.19.3
Summary of Significant Accounting Policies (Details Narrative) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Accounting Policies [Abstract]        
Unrealized gain on debt securities $ 923
Held-to-maturity debt securities    
XML 20 R26.htm IDEA: XBRL DOCUMENT v3.19.3
Property and Equipment - Schedule of Property and Equipment (Details) - USD ($)
9 Months Ended
Sep. 30, 2019
Dec. 31, 2018
Property, Plant and Equipment [Line Items]    
Total property and equipment $ 36,336 $ 34,747
Accumulated depreciation (19,137) (14,587)
Total property and equipment, net $ 17,199 20,160
Computers and Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Estimated Life 5 years  
Total property and equipment $ 17,178 15,589
Furniture and Fixtures [Member]    
Property, Plant and Equipment [Line Items]    
Estimated Life 7 years  
Total property and equipment $ 19,158 $ 19,158
XML 21 R4.htm IDEA: XBRL DOCUMENT v3.19.3
Condensed Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Operating costs and expenses:        
Research and development $ 1,036,689 $ 3,459,681 $ 6,044,580 $ 6,180,607
Patent costs 20,867 59,068 139,436 170,418
General and administrative 1,122,825 1,144,750 3,621,888 3,957,545
Total operating costs and expenses 2,180,381 4,663,499 9,805,904 10,308,570
Operating loss (2,180,381) (4,663,499) (9,805,904) (10,308,570)
Other income:        
Interest income 13,172 17,237 117,777 64,965
Total other income 13,172 17,237 117,777 64,965
Net loss (2,167,209) (4,646,263) (9,688,127) (10,243,605)
Other comprehensive income:        
Unrealized gain on debt securities 923
Comprehensive loss $ (2,167,209) $ (4,646,262) $ (9,687,204) $ (10,243,605)
Net loss per common share - basic and diluted $ (0.23) $ (0.86) $ (1.09) $ (2.00)
Weighted average common shares outstanding - basic and diluted 9,507,636 5,373,769 8,873,947 5,129,351
XML 22 R8.htm IDEA: XBRL DOCUMENT v3.19.3
Basis of Presentation
9 Months Ended
Sep. 30, 2019
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Basis of Presentation

NOTE 2 - BASIS OF PRESENTATION

 

The accompanying interim period unaudited condensed financial statements have been prepared in accordance with accounting principles generally accepted in the United States of America (“GAAP”) and applicable rules and regulations of the U.S. Securities and Exchange Commission (“SEC”) regarding interim financial reporting. Accordingly, they do not include all of the information and footnotes required by GAAP for complete financial statements. However, in the opinion of management, all adjustments consisting of normal recurring adjustments considered necessary for a fair presentation of the financial position and results of operations have been included and management believes the disclosures that are made are adequate to make the information presented not misleading.

 

The condensed balance sheets at December 31, 2018 have been derived from the audited financial statements included in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2018 filed with the SEC on April 1, 2019 (the “2018 Annual Report”), but does not include all of the information and footnotes required by GAAP for complete financial statements.

 

The results for the three and nine months ended September 30, 2019 are not necessarily indicative of the results expected for the full fiscal year or any other period. The accompanying interim period unaudited condensed financial statements and related financial information included in this Quarterly Report on Form 10-Q (“Quarterly Report”) should be read in conjunction with the audited financial statements and notes thereto included in the Company’s 2018 Annual Report.

 

All common share amounts and per share amounts have been adjusted to reflect a 1-for-10 reverse stock split of the Company’s common stock effected on March 23, 2018.

  

Going Concern and Liquidity

 

The accompanying interim period unaudited condensed financial statements have been prepared assuming the Company will continue as a going concern, which contemplates, among other things, the realization of assets and satisfaction of liabilities in the normal course of business.

 

The Company has not generated any product revenue and has not achieved profitable operations to date. For the nine months ended September 30, 2019, the Company had a net loss of approximately $9.7 million and had net cash used in operating activities of approximately $12.9 million. At September 30, 2019, the Company had net working capital of approximately $0.1 million, an accumulated deficit of approximately $79.9 million, and cash and cash equivalents of approximately $2.0 million.

 

In September 2019, the Company announced that its Phase 3 clinical trial of RP-G28 for LI failed to demonstrate statistical significance in its pre-specified primary and secondary endpoints. While the Company is continuing to analyze the results of the trial to better understand the data and clinical outcomes to assess a path forward for RP-G28, no further development efforts of RP-G28 are currently ongoing. The Company is currently exploring and evaluating potential strategic alternatives to enhance shareholder value, which may include an acquisition, merger, reverse merger, other business combination, sale of assets, licensing or other strategic transaction.

 

There is no assurance that profitable operations will ever be achieved, and, if achieved, could be sustained on a continuing basis. The Company’s operating expenses have decreased significantly since the completion of its Phase 3 clinical trial of RP-G28 and the Company has made additional operating expense reductions following the announcement of the trial results, including reductions to executive and board compensation. The Company will continue to make further reductions as necessary. However, any future development activities, clinical and pre-clinical testing, and commercialization of the Company’s products will require significant financing. These matters, among others, raise substantial doubt about the Company’s ability to continue as a going concern.

 

Since inception, the operations of the Company have been funded through the sale of common shares, preferred shares, warrants and convertible debt. Our announcement related to the results of our Phase 3 clinical trial of RP-G28 has significantly depressed our stock price and may severely impair our ability to raise additional funds. Management cannot be certain that additional funding will be available on acceptable terms, or at all. To the extent that the Company is able to raise additional funds by issuing equity securities, the Company’s stockholders may experience significant dilution. Any debt financing, if available, may involve restrictive covenants that could impact the Company’s ability to conduct business. If the Company is not able to raise additional capital on acceptable terms, the Company may have to (i) discontinue the development and/or commercialization of RP-G28; (ii) seek collaborators for the development of RP-G28 on terms that are less favorable than might otherwise be available; or (iii) relinquish or otherwise dispose of rights to RP-G28.

 

The financial statements do not include any adjustments that might be necessary if the Company is unable to continue as a going concern.

XML 23 R23.htm IDEA: XBRL DOCUMENT v3.19.3
Summary of Significant Accounting Policies - Schedule of Supplemental Cash Flow Information Related to Leases (Details) - USD ($)
9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Accounting Policies [Abstract]    
Operating cash flows from operating lease $ 86,234  
Operating lease asset obtained in exchange for lease obligation: Operating lease $ 198,319
Operating lease: Remaining lease term 1 year 1 month 6 days  
Operating lease: Discount rate 6.00%  
XML 24 R27.htm IDEA: XBRL DOCUMENT v3.19.3
Commitments and Contingencies (Details Narrative)
3 Months Ended 9 Months Ended
Sep. 30, 2019
USD ($)
Sep. 30, 2018
USD ($)
Sep. 30, 2019
USD ($)
Sep. 30, 2018
USD ($)
Jul. 09, 2015
ft²
Rent expense $ 29,000 $ 29,000 $ 88,000 $ 88,000  
Lease renewal term 5 years   5 years    
Lease, option to extend     The Company has the option to extend the term of the lease for one five-year term, provided that the rent would be subject to market adjustment at the beginning of the renewal term.    
California limited partnership [Member]          
Area of lease | ft²         2,780
Lease agreement term         61 months
Months 2 Through 13 [Member]          
Rent expense     $ 9,174    
Months 50 Through 61 [Member]          
Rent expense     $ 10,325    
XML 25 R9.htm IDEA: XBRL DOCUMENT v3.19.3
Summary of Significant Accounting Policies
9 Months Ended
Sep. 30, 2019
Accounting Policies [Abstract]  
Summary of Significant Accounting Policies

NOTE 3 - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

 

There have been no material changes in the Company’s significant accounting policies as of and for the nine months ended September 30, 2019, as compared to the significant accounting policies described in the Company’s 2018 Annual Report, except for the recent adoption of the new lease accounting pronouncement as described below.

 

Use of Estimates

 

The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities as of the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates.

 

Cash and Cash Equivalents

 

Cash consists of amounts held in financial institutions that are immediately available to the Company. The funds are maintained at stable financial institutions, generally at amounts in excess of federally insured limits. Cash equivalents include money market funds and held-to-maturity securities with a maturity date of 90 days or less. As of September 30, 2019, cash and cash equivalents consisted of bank deposits, cash and investments in money market funds. The Company has not realized any losses in such accounts and management believes that the Company is not exposed to significant credit risk due to the financial position of the depository institutions at which those deposits are held.

 

Investments in Marketable Securities

 

Investments in marketable securities are held in a custodial account at a financial institution and managed by the Company’s capital advisors based on the Company’s investment guidelines. All of the Company’s investments in marketable securities are classified as available-for-sale debt securities and are carried at fair value. Interest on these securities, as well as the amortization of discounts and premiums, is included in interest income in the statements of operations. The unrealized gains and losses on these securities are excluded from earnings and reported in other comprehensive income until realized, except when the declines in value are considered to be other than temporary. Other than temporary impairment losses related to credit losses are considered to be realized losses. When available-for-sale debt securities are sold, the cost of the securities is specifically identified and is used to determine the realized gain or loss. Securities classified as current assets have maturity dates of less than or equal to one year from the balance sheet date.

 

Operating Leases

 

The Company determines if a contract contains a lease at inception. The Company’s material operating lease relates to a single office space. Operating lease assets and liabilities are recognized at the lease commencement date. Operating lease liabilities represent the present value of lease payments not yet paid. Operating lease assets represent the Company’s right to use an underlying asset and are based upon the operating lease liabilities adjusted for prepayments or accrued lease payments, initial direct costs, lease incentives, and impairment of operating lease assets. To determine the present value of lease payments not yet paid, the Company estimates incremental secured borrowing rates corresponding to the maturities of the leases. As the Company has no outstanding debt or committed credit facilities, secured or otherwise, the Company estimates this rate based on prevailing financial market conditions, comparable company and credit analysis, and management judgment.

 

The Company’s leases typically contain rent escalations over the lease term. The Company recognize expense for these leases on a straight-line basis over the lease term. Additionally, tenant incentives used to fund leasehold improvements are recognized when earned and reduce the Company’s right-of-use (“ROU”) asset related to the lease. These are amortized through the ROU asset as reductions of expense over the lease term. The Company’s lease agreement does not contain any material residual value guarantees or material restrictive covenants. The Company has no lease agreements with lease and non-lease components.

 

Related to the adoption of Topic 842, the Company’s policy elections were as follows:

 

Separation of lease and non-lease components   While the Company does not currently have any lease agreement with lease and non-lease components, the Company elected this expedient to account for lease and non-lease components as separate components.
     
Short-term policy   The Company has elected the short-term lease recognition exemption for all applicable classes of underlying assets. Short-term disclosures include only those leases with a term greater than one month and 12 months or less, and expense is recognized on a straight-line basis over the lease term. Leases with an initial term of 12 months or less, that do not include an option to purchase the underlying asset that the Company is reasonably certain to exercise, are not recorded on the balance sheet.

 

Other information related to the Company’s leases is provided below.

 

    Nine Months Ended
September 30, 2019
 
Supplemental Cash Flows Information        
Cash paid for amounts included in the measurement of lease liability:        
Operating cash flows from operating lease     86,234  
Operating lease asset obtained in exchange for lease obligation:        
Operating lease   $ 198,319  
Remaining lease term        
Operating lease     1.1 years  
Discount rate        
Operating lease     6.00 %

 

Future payments under non-cancelable extended operating leases having initial or remaining terms of one year or more are as follows for the remaining fiscal year and thereafter:

 

Future minimum lease payments year ending December 31,      
2019 (remaining)   $ 30,675  
2020     103,254  
Total future minimum lease payments, undiscounted     133,929  
Less imputed interest     (4,581 )
Present value of lease liabilities   $ 129,348  
         
Operating lease liabilities reported as of September 30, 2019:        
Operating lease liabilities-current   $ 119,074  
Operating lease liabilities-non-current     10,274  
Total   $ 129,348  

 

Equity-linked Financial Instruments

 

The Company classifies outstanding common stock warrants with down-round features as equity, if the instrument would otherwise be classified in equity absent the down-round feature. The Company will recognize the value of a down-round feature when it is triggered and the warrant’s strike price has been adjusted downward, as a deemed dividend and reduction of income available to common stockholders in computing basic earnings per share.

 

Net Loss Per Share

 

The Company determines basic loss per share and diluted loss per share in accordance with the provisions of Accounting Standards Codification (“ASC”) 260, “Earnings per Share.” Basic net loss per share was calculated by dividing net loss by the weighted-average common shares outstanding during the period. Diluted net loss per share was calculated by dividing net loss by the weighted-average common shares outstanding during the period using the treasury stock method or the two-class method, whichever is more dilutive. The potentially dilutive stock options issued under the 2015 Plan (described in Note 8), Series A, B and C Convertible Preferred Stock (described in Note 6) and warrants to purchase the Company’s common stock (described in Notes 6 and 7) were not considered in the computation of diluted net loss per share because they would be anti-dilutive.

 

Comprehensive Income (Loss)

 

Comprehensive income (loss) is defined as the change in equity during a period from transactions and other events and circumstances from non-owner sources. The Company is required to record all components of comprehensive income (loss) in the financial statements in the period in which they are recognized. Net income (loss) and other comprehensive income (loss), including foreign currency translation adjustments and unrealized gains and losses on investments are reported, net of their related tax effect, to arrive at comprehensive income (loss). For the nine months ended September 30, 2019, comprehensive income consisted of unrealized gains on investments in available-for-sale debt securities. There were no unrealized gains (losses) on investments in available-for-sale debt securities and held-to-maturity debt securities for the nine months ended September 30, 2018.

 

Recent Accounting Pronouncements

 

In June 2016, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) No. 2016-13, Financial Instruments – Credit Losses (Topic 326): Measurement of Credit Losses on Financial Instruments, an amendment that modifies the measurement recognition of credit losses for most financial assets and certain other instruments. The amendment updates the guidance for measuring and recording credit losses on financial assets measured at amortized cost by replacing the “incurred loss” model with an “expected loss” model. Accordingly, these financial assets will be presented at the net amount expected to be collected. The amendment also requires that credit losses related to available-for-sale debt securities be recorded as an allowance through net income rather than reducing the carrying amount under the current, other-than-temporary-impairment model. The guidance is effective for public business entities that are SEC filers. The amendments in ASU No. 2016-13 are effective for fiscal years beginning after December 15, 2019, including interim periods within those fiscal years. For all other public business entities, the amendments in this ASU are effective for fiscal years beginning after December 15, 2020, including interim periods within those fiscal years. The Company does not expect the adoption of this guidance will have a material impact on its financial statements.

 

In August 2018, the FASB issued ASU No. 2018-13, “Fair Value Measurement (Topic 820): Disclosure Framework — Changes to the Disclosure Requirements for Fair Value Measurement”, an amendment to the accounting guidance on fair value measurements. The guidance modifies the disclosure requirements on fair value measurements, including the removal of disclosures of the amount of and reasons for transfers between Level 1 and Level 2 of the fair value hierarchy, the policy for timing of transfers between levels, and the valuation processes for Level 3 fair value measurements. The guidance also adds certain disclosure requirements related to Level 3 fair value measurements. The guidance is effective for fiscal years, and interim periods within those fiscal years, beginning after December 15, 2019. The Company does not expect the adoption of this guidance will have a material impact on its financial statements.

 

In June 2016, the FASB issued ASU 2016-13, Financial Instruments—Credit Losses (Topic 326): Measurement of Credit Losses on Financial Instruments (ASU 2016-13) and also issued subsequent amendments to the initial guidance: ASU 2018-19, ASU 2019-04, and ASU 2019-05 (collectively, “Topic 326”). Topic 326 requires measurement and recognition of expected credit losses for financial assets held. The effective date and transition methodology for the amendments in Topic 326 are the same as in ASU 2016-13. The Company does not expect the adoption of this guidance will have a material impact on its financial statements.

 

Other accounting standard updates effective after September 30, 2019 are not expected to have a material impact on the Company’s financial statements.

 

Recently Adopted Accounting Pronouncements

 

In February 2016, the FASB issued ASU No. 2016-02, Leases (Topic 842). Under this guidance, an entity is required to recognize ROU assets and corresponding lease liabilities on its balance sheets and disclose key information about leasing arrangements. In July 2018, the FASB issued ASU No. 2018-11, Leases (Topic 842) Targeted Improvements, which provides for an alternative transition method by allowing companies to continue to use the legacy guidance in Topic 840, Leases, including its disclosure requirements, in the comparative periods presented in the year of adoption of the new leases standard and recognize a cumulative-effect adjustment to the opening balance of retained earnings in the period of adoption rather than the earliest period presented.

 

The Company elected the available package of practical expedients, but not the hindsight practical expedient, and implemented internal controls to enable the preparation of financial information on adoption as of January 1, 2019.

 

The standard had a material impact on the Company’s condensed balance sheets, but did not have an impact on its statements of operations and comprehensive loss. The most significant impact was the recognition of a ROU asset and lease liability for the Company’s sole operating lease—the Company had no finance leases. Adoption of the standard did not require the Company to restate previously reported results as it elected to apply a modified retrospective approach at the beginning of the period of adoption rather than at the beginning of the earliest comparative period presented.

 

In June 2018, the FASB issued ASU No. 2018-07, Improvements to Nonemployee Share-Based Payment Accounting, which expands the scope of Topic 718 Compensation—Stock Compensation, to include share-based payments issued to nonemployees for goods or services. Consequently, the accounting for share-based payments to nonemployees and employees will be substantially aligned. ASU No. 2018-07 supersedes Subtopic 505-50 Equity—Equity-Based Payments to Non-Employees. The amendments implemented by ASU No. 2018-07 are effective for fiscal years beginning after December 15, 2018, including interim periods within that fiscal year. Early adoption is permitted, but no earlier than an entity’s adoption date of Topic 606. The Company adopted ASU 2018-07 on January 1, 2019 and it did not have a material effect on its results of operations, financial position or cash flows.

 

In August 2018, the SEC adopted final rules under SEC Release No. 33-10532, Disclosure Update and Simplification, amending certain SEC disclosure requirements that were redundant, duplicative, overlapping, outdated or superseded. In addition, the amendments expanded the disclosure requirements on the analysis of stockholders’ equity for interim financial statements. Under the amendments, an analysis of changes in each caption of stockholders’ equity presented in the balance sheets must be provided in a note or separate statement. The analysis must present a reconciliation of the beginning balance to the ending balance of each period for which a statement of comprehensive income is required to be filed. These final rules became effective on November 5, 2018, with issuers required to provide their analysis of stockholders’ equity in quarterly reports on Form 10-Q beginning with reports for the quarter ended March 31, 2019. The Company included the analysis of changes in stockholders’ equity in the interim period unaudited condensed financial statements for the quarter ended March 31, 2019, has included it in this Quarterly Report, and will continue to do so in the Company’s quarterly reports on Form 10-Q in the future. The Company adopted these SEC amendments on January 1, 2019 and it did not have a material impact on the Company’s financial position, results of operations, cash flows or stockholders’ equity.

XML 26 R5.htm IDEA: XBRL DOCUMENT v3.19.3
Condensed Statements of Changes in Stockholders' Equity (Unaudited) - USD ($)
Series A Preferred Stock [Member]
Series B Preferred Stock [Member]
Series C Preferred Stock [Member]
Common Stock [Member]
Paid-in Capital [Member]
Accumulated Deficit [Member]
Other Comprehensive Loss [Member]
Total
Balance at Dec. 31, 2017 $ 5,128,536 $ 4,941 $ 68,323,939 $ (53,331,434) $ 20,125,982
Balance, shares at Dec. 31, 2017 9,140 4,940,652        
Conversion of preferred shares into common stock $ (179,555) $ 80 179,475
Conversion of preferred shares into common stock, shares (320) 80,000        
Stock-based compensation 212,608 212,608
Net loss (2,012,690) (2,012,690)
Balance at Mar. 31, 2018 $ 4,948,981 $ 5,021 68,716,022 (55,344,124) 18,325,900
Balance, shares at Mar. 31, 2018 8,820 5,020,652        
Balance at Dec. 31, 2017 $ 5,128,536 $ 4,941 68,323,939 (53,331,434) 20,125,982
Balance, shares at Dec. 31, 2017 9,140 4,940,652        
Payout to stockholders for fractional shares               3,256
Net loss               (10,243,605)
Balance at Sep. 30, 2018 $ 3,344,209 $ 5,735 70,665,970 (63,575,039) 10,440,875
Balance, shares at Sep. 30, 2018 5,960 5,734,639        
Balance at Mar. 31, 2018 $ 4,948,981 $ 5,021 68,716,022 (55,344,124) 18,325,900
Balance, shares at Mar. 31, 2018 8,820 5,020,652        
Conversion of preferred shares into common stock $ (706,998) $ 314 706,683
Conversion of preferred shares into common stock, shares (1,260) 315,000        
Stock-based compensation 178,074 178,074
Payout to stockholders for fractional shares (3,256) (3,256)
Net loss (3,584,652) (3,584,652)
Balance at Jun. 30, 2018 $ 4,241,983 $ 5,335 69,597,523 (58,928,776) 14,916,065
Balance, shares at Jun. 30, 2018 7,560 5,334,639        
Conversion of preferred shares into common stock $ (897,774) $ 400 897,374
Conversion of preferred shares into common stock, shares (1,600) 400,000        
Stock-based compensation 171,073 171,073
Net loss (4,646,263) (4,646,263)
Balance at Sep. 30, 2018 $ 3,344,209 $ 5,735 70,665,970 (63,575,039) 10,440,875
Balance, shares at Sep. 30, 2018 5,960 5,734,639        
Balance at Dec. 31, 2018 $ 2,289,324 $ 3,906,931 $ 1,880,000 $ 6,037 71,505,160 (70,200,145) (923) 9,386,384
Balance, shares at Dec. 31, 2018 4,080 5,608 1,880 6,036,562        
Stock-based compensation 146,491 146,491
Conversion of Series B preferred shares into common stock $ (1,816,732) $ 2,005 1,814,727
Conversion of Series B preferred shares into common stock, shares (2,608) 2,005,770        
Conversion of Series C preferred shares into common stock $ (1,640,000) $ 1,000 1,639,000
Conversion of Series C preferred shares into common stock, shares (1,640) 1,000,000        
Unrealized gain on investment in marketable securities (923) 2,434 1,511
Net loss (4,705,766) (4,705,766)
Balance at Mar. 31, 2019 $ 2,289,324 $ 2,090,199 $ 240,000 $ 9,042 75,105,378 (74,906,834) 1,511 4,828,620
Balance, shares at Mar. 31, 2019 4,080 3,000 240 9,042,332        
Balance at Dec. 31, 2018 $ 2,289,324 $ 3,906,931 $ 1,880,000 $ 6,037 71,505,160 (70,200,145) (923) 9,386,384
Balance, shares at Dec. 31, 2018 4,080 5,608 1,880 6,036,562        
Payout to stockholders for fractional shares              
Net loss               (9,688,127)
Balance at Sep. 30, 2019 $ 2,289,324 $ 1,288,956 $ 240,000 $ 9,927 76,122,975 (79,888,272) 62,910
Balance, shares at Sep. 30, 2019 4,080 1,850 240 9,926,956        
Balance at Mar. 31, 2019 $ 2,289,324 $ 2,090,199 $ 240,000 $ 9,042 75,105,378 (74,906,834) 1,511 4,828,620
Balance, shares at Mar. 31, 2019 4,080 3,000 240 9,042,332        
Stock-based compensation 122,703 122,703
Unrealized gain on investment in marketable securities $ 923 $ (1,511) $ (588)
Fractional shares adjustment (2)
Net loss $ (2,815,152) $ (2,815,152)
Balance at Jun. 30, 2019 $ 2,289,324 $ 2,090,199 $ 240,000 $ 9,042 75,228,081 (77,721,063) 2,135,583
Balance, shares at Jun. 30, 2019 4,080 3,000 240 9,042,330        
Stock-based compensation 94,536 94,536
Conversion of Series B preferred shares into common stock $ (801,243) $ 885 800,358
Conversion of Series B preferred shares into common stock, shares (1,150) 884,626        
Net loss (2,167,209) (2,167,209)
Balance at Sep. 30, 2019 $ 2,289,324 $ 1,288,956 $ 240,000 $ 9,927 $ 76,122,975 $ (79,888,272) $ 62,910
Balance, shares at Sep. 30, 2019 4,080 1,850 240 9,926,956        
XML 27 R1.htm IDEA: XBRL DOCUMENT v3.19.3
Document and Entity Information - shares
9 Months Ended
Sep. 30, 2019
Nov. 07, 2019
Document And Entity Information    
Entity Registrant Name RITTER PHARMACEUTICALS INC  
Entity Central Index Key 0001460702  
Document Type 10-Q  
Document Period End Date Sep. 30, 2019  
Amendment Flag false  
Current Fiscal Year End Date --12-31  
Entity Current Reporting Status Yes  
Entity Interactive Data Current Yes  
Entity Filer Category Non-accelerated Filer  
Entity Small Business Flag true  
Entity Emerging Growth Company true  
Entity Ex Transition Period false  
Entity Shell Company false  
Entity Common Stock, Shares Outstanding   10,164,756
Document Fiscal Period Focus Q3  
Document Fiscal Year Focus 2019  
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MV)L 'TK!@ 1 " 0 !R='1R+3(P,3DP.3,P+GAM;%!+ M 0(4 Q0 ( $RO;4^#)Y4;APP -QO 1 " 0>< !R M='1R+3(P,3DP.3,P+GAS9%!+ 0(4 Q0 ( $RO;4]:<0BST T !ND 5 M " ;VH !R='1R+3(P,3DP.3,P7V-A;"YX;6Q02P$"% ,4 M " !,KVU/-D)Y*;8< "'VP$ %0 @ ' M@ &UL4$L! A0#% @ 3*]M3\43;GAC/P C*P# !4 M ( !J=, ')T='(M,C Q.3 Y,S!?;&%B+GAM;%!+ 0(4 Q0 M ( $RO;4^NJ XML 30 R32.htm IDEA: XBRL DOCUMENT v3.19.3
Stock-Based Compensation - Schedule of Assumptions Used in Black-Scholes Option-Pricing Method (Details) - $ / shares
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Expected dividend yield 0.00% 0.00% 0.00% 0.00%
Expected stock-price volatility, minimum 69.00% 48.89% 46.33% 46.47%
Expected stock-price volatility, maximum 69.38% 50.22% 69.38% 53.11%
Risk-free interest rate, minimum 1.47% 2.78% 1.47% 2.46%
Risk-free interest rate, maximum 1.54% 3.07% 2.60% 3.07%
Stock price $ 1.04      
Minimum [Member]        
Expected average term of options 5 years 7 years 5 years 5 years
Stock price   $ 1.85 $ 0.60 $ 1.85
Maximum [Member]        
Expected average term of options 7 years 10 years 7 years 10 years
Stock price   $ 2.22 $ 1.04 $ 3.40
XML 31 R19.htm IDEA: XBRL DOCUMENT v3.19.3
Property and Equipment (Tables)
9 Months Ended
Sep. 30, 2019
Property, Plant and Equipment [Abstract]  
Schedule of Property and Equipment

Property and equipment consists of the following:

 

    Estimated Life   September 30, 2019     December 31, 2018  
Computers and equipment   5 years   $ 17,178     $ 15,589  
Furniture and fixtures   7 years     19,158       19,158  
Total property and equipment         36,336       34,747  
Accumulated depreciation         (19,137 )     (14,587 )
Total property and equipment, net       $ 17,199     $ 20,160  

XML 32 R11.htm IDEA: XBRL DOCUMENT v3.19.3
Commitments and Contingencies
9 Months Ended
Sep. 30, 2019
Commitments and Contingencies Disclosure [Abstract]  
Commitments and Contingencies

NOTE 5 - COMMITMENTS AND CONTINGENCIES

 

Master Services Agreement

 

In May 2018, the Company entered into an Amended and Restated Master Services Agreement (“Service Agreement”) with a clinical research organization (“CRO”), pursuant to which the CRO will perform certain services related to the management and execution of certain clinical trials involving RP-G28. The Services Agreement supersedes the Master Service Agreement, dated August 30, 2016, by and between the Company and the CRO. The precise services to be performed by the CRO under the Services Agreement will be mutually agreed upon by the parties in writing and set forth in one or more task orders. The Company is not obligated to purchase any minimum or specific volume or dollar amount of services under the Services Agreement.

 

The term of the Services Agreement is four years from the effective date of the Service Agreement unless earlier terminated. The Company may terminate the Services Agreement or any task without cause immediately upon giving the CRO notice of such termination. The CRO may terminate a task order if the Company has materially defaulted on its obligations under the Services Agreement or any task order and has not cured such material default with advance notice to the Company, as described in the Services Agreement.

 

Lease Agreement

 

On July 9, 2015, the Company entered into a lease with a California limited partnership, pursuant to which the Company leased approximately 2,780 square feet of office space in Los Angeles, California for its headquarters. The lease provides for a term of sixty-one (61) months, commencing on October 1, 2015. The Company paid no rent for the first month of the term and paid base rent of $9,174 per month for months 2 through 13 of the term, with increasing base rent for each twelve-month period thereafter under the term of the lease to a maximum of $10,325 per month for months 50 through 61. The base rent payments do not include the Company’s proportionate share of any operating expenses, including real estate taxes. The Company has the option to extend the term of the lease for one five-year term, provided that the rent would be subject to market adjustment at the beginning of the renewal term.

 

Rent expense, which is recognized on a straight-line basis over the lease term, was approximately $29,000 for each of the three months ended September 30, 2019 and 2018, and approximately $88,000 for each of the nine months ended September 30, 2019 and 2018 and is recorded in general and administrative expenses in the accompanying unaudited condensed statements of operations.

 

Legal

 

From time to time, the Company may be party to legal claims and proceedings that arise in the ordinary course of business, which may relate to our operations or assets. These may include disputes and lawsuits related to intellectual property, licensing, contract law and employee relations matters. Periodically, the Company reviews the status of significant matters, if any exist, and assesses its potential financial exposure. If the potential loss from any claim or legal claim is considered probable and the amount can be estimated, the Company accrues a liability for the estimated loss. Legal proceedings are subject to uncertainties, and the outcomes are difficult to predict. Because of such uncertainties, accruals are based on the best information available at the time. As additional information becomes available, the Company reassesses the potential liability related to pending claims and litigation. We do not believe that any individual legal claim or proceeding that is currently pending is material to the Company or that these claims and proceedings in the aggregate are material to the Company.

XML 33 R15.htm IDEA: XBRL DOCUMENT v3.19.3
Related Party Transactions
9 Months Ended
Sep. 30, 2019
Related Party Transactions [Abstract]  
Related Party Transactions

NOTE 9 - RELATED PARTY TRANSACTIONS

 

A director of the Company is a managing director of Javelin Venture Partners GP, LLC, the general partner of Javelin Venture Partners GP, L.P., which holds a significant investment in the Company’s common stock and warrants. Two directors of the Company have acted as a managing director of Stonehenge Partners, LLC, which holds an investment in the Company’s common stock.

 

Other than as described above, the Company has not entered into or been a participant in any transaction in which a related party had or will have a direct or indirect material interest for the nine months ended September 30, 2019.

XML 34 R21.htm IDEA: XBRL DOCUMENT v3.19.3
Basis of Presentation (Details Narrative) - USD ($)
3 Months Ended 9 Months Ended
Mar. 23, 2018
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2018
Organization, Consolidation and Presentation of Financial Statements [Abstract]                    
Reverse stock split 1-for-10 reverse stock split       1-for-10 reverse stock          
Net loss   $ (2,167,209) $ (2,815,152) $ (4,705,766) $ (4,646,263) $ (3,584,652) $ (2,012,690) $ (9,688,127) $ (10,243,605)  
Net cash used in operating activities               (12,851,824) $ (10,130,131)  
Net working capital   100,000           100,000    
Accumulated deficit   (79,888,272)           (79,888,272)   $ (70,200,145)
Cash and cash equivalents   $ 1,957,395           $ 1,957,395   $ 7,812,259
XML 35 R25.htm IDEA: XBRL DOCUMENT v3.19.3
Property and Equipment (Details Narrative) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Property, Plant and Equipment [Abstract]        
Depreciation expense $ 1,600 $ 1,500 $ 4,600 $ 4,300
XML 36 R29.htm IDEA: XBRL DOCUMENT v3.19.3
Warrants (Details Narrative)
Sep. 30, 2019
$ / shares
shares
Issuance of warrants to purchase of common stock shares | shares 8,413,017
Weighted average exercise price of warrants $ 1.78
Warrant expiration date Nov. 30, 2023
Minimum [Member]  
Warrants exercise prices ranging $ 1.30
Maximum [Member]  
Warrants exercise prices ranging $ 93.00
XML 37 R7.htm IDEA: XBRL DOCUMENT v3.19.3
Organization and Principal Activities
9 Months Ended
Sep. 30, 2019
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Organization and Principal Activities

NOTE 1 - ORGANIZATION AND PRINCIPAL ACTIVITIES

 

Ritter Pharmaceuticals, Inc. (“Ritter” or the “Company”) is a Delaware corporation headquartered in Los Angeles, California. The Company was formed as a Nevada limited liability company in March 2004, under the name Ritter Natural Sciences, LLC, and converted into a Delaware corporation in September 2008.

 

Since its inception, Ritter Pharmaceuticals, Inc. has been focused on the development of innovative therapeutic products that modulate the gut microbiome to treat gastrointestinal diseases. The Company’s only product candidate, RP-G28, is an orally administered, high purity galacto-oligosaccharide for the treatment of lactose intolerance (“LI”), a condition that affects millions of people worldwide. RP-G28 is designed to selectively stimulate the growth of lactose-metabolizing bacteria in the colon, thereby effectively adapting the gut microbiome to assist in digesting lactose (the sugar found in milk) that reaches the large intestine. The Company completed enrollment in its Phase 3 clinical trial of RP-G28 known as “Liberatus” in March 2019 and last patient visit in July 2019. In September 2019, the Company announced that its Phase 3 clinical trial of RP-G28 for LI failed to demonstrate statistical significance in its pre-specified primary and secondary endpoints. While the Company is continuing to analyze the results of the trial to better understand the data and clinical outcomes to assess a path forward for RP-G28, no further development efforts of RP-G28 are currently ongoing.

 

In October 2019, the Company announced that it has engaged A.G.P./Alliance Global Partners (“A.G.P.”) as financial advisor to explore and evaluate potential strategic alternatives to enhance shareholder value, which may include an acquisition, merger, reverse merger, other business combination, sale of assets, licensing or other strategic transaction.

 

The Company operates in one business segment focused on the development and commercialization of therapeutic products that modulate the gut microbiome to treat gastrointestinal diseases. The Company is not organized by market and is managed and operated as one business. A single management team reports to the chief operating decision maker, the Chief Executive Officer. The Company does not currently operate any separate lines of business or separate business entities.

XML 38 R3.htm IDEA: XBRL DOCUMENT v3.19.3
Condensed Balance Sheets (Parenthetical) - $ / shares
Sep. 30, 2019
Dec. 31, 2018
Preferred stock, par value $ 0.001  
Preferred stock, shares authorized 15,000,000  
Common stock, par value $ 0.001 $ 0.001
Common stock, shares authorized 225,000,000 225,000,000
Common stock, shares issued 9,926,956 6,036,562
Common stock, shares outstanding 9,926,956 6,036,562
Series A Preferred Stock [Member]    
Preferred stock, par value $ 0.001 $ 0.001
Preferred stock, shares authorized 9,500 9,500
Preferred stock, shares issued 4,080 4,080
Preferred stock, shares outstanding 4,080 4,080
Series B Preferred Stock [Member]    
Preferred stock, par value $ 0.001 $ 0.001
Preferred stock, shares authorized 6,000 6,000
Preferred stock, shares issued 1,850 5,608
Preferred stock, shares outstanding 1,850 5,608
Series C Preferred Stock [Member]    
Preferred stock, par value $ 0.001 $ 0.001
Preferred stock, shares authorized 1,880 1,880
Preferred stock, shares issued 240 1,880
Preferred stock, shares outstanding 240 1,880
XML 39 R13.htm IDEA: XBRL DOCUMENT v3.19.3
Warrants
9 Months Ended
Sep. 30, 2019
Warrants and Rights Note Disclosure [Abstract]  
Warrants

NOTE 7 - WARRANTS

 

Warrants to purchase an aggregate of 8,413,017 shares of the Company’s common stock were outstanding at September 30, 2019. These warrants are all vested and exercisable, have exercise prices ranging from $1.30 to $93.00 per share, with a weighted average exercise price of $1.78, and expire at various dates through November 2023.

XML 40 R17.htm IDEA: XBRL DOCUMENT v3.19.3
Summary of Significant Accounting Policies (Policies)
9 Months Ended
Sep. 30, 2019
Accounting Policies [Abstract]  
Use of Estimates

Use of Estimates

 

The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities as of the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates.

Cash and Cash Equivalents

Cash and Cash Equivalents

 

Cash consists of amounts held in financial institutions that are immediately available to the Company. The funds are maintained at stable financial institutions, generally at amounts in excess of federally insured limits. Cash equivalents include money market funds and held-to-maturity securities with a maturity date of 90 days or less. As of September 30, 2019, cash and cash equivalents consisted of bank deposits, cash and investments in money market funds. The Company has not realized any losses in such accounts and management believes that the Company is not exposed to significant credit risk due to the financial position of the depository institutions at which those deposits are held.

Investments in Marketable Securities

Investments in Marketable Securities

 

Investments in marketable securities are held in a custodial account at a financial institution and managed by the Company’s capital advisors based on the Company’s investment guidelines. All of the Company’s investments in marketable securities are classified as available-for-sale debt securities and are carried at fair value. Interest on these securities, as well as the amortization of discounts and premiums, is included in interest income in the statements of operations. The unrealized gains and losses on these securities are excluded from earnings and reported in other comprehensive income until realized, except when the declines in value are considered to be other than temporary. Other than temporary impairment losses related to credit losses are considered to be realized losses. When available-for-sale debt securities are sold, the cost of the securities is specifically identified and is used to determine the realized gain or loss. Securities classified as current assets have maturity dates of less than or equal to one year from the balance sheet date.

Operating Leases

Operating Leases

 

The Company determines if a contract contains a lease at inception. The Company’s material operating lease relates to a single office space. Operating lease assets and liabilities are recognized at the lease commencement date. Operating lease liabilities represent the present value of lease payments not yet paid. Operating lease assets represent the Company’s right to use an underlying asset and are based upon the operating lease liabilities adjusted for prepayments or accrued lease payments, initial direct costs, lease incentives, and impairment of operating lease assets. To determine the present value of lease payments not yet paid, the Company estimates incremental secured borrowing rates corresponding to the maturities of the leases. As the Company has no outstanding debt or committed credit facilities, secured or otherwise, the Company estimates this rate based on prevailing financial market conditions, comparable company and credit analysis, and management judgment.

 

The Company’s leases typically contain rent escalations over the lease term. The Company recognize expense for these leases on a straight-line basis over the lease term. Additionally, tenant incentives used to fund leasehold improvements are recognized when earned and reduce the Company’s right-of-use (“ROU”) asset related to the lease. These are amortized through the ROU asset as reductions of expense over the lease term. The Company’s lease agreement does not contain any material residual value guarantees or material restrictive covenants. The Company has no lease agreements with lease and non-lease components.

 

Related to the adoption of Topic 842, the Company’s policy elections were as follows:

 

Separation of lease and non-lease components   While the Company does not currently have any lease agreement with lease and non-lease components, the Company elected this expedient to account for lease and non-lease components as separate components.
     
Short-term policy   The Company has elected the short-term lease recognition exemption for all applicable classes of underlying assets. Short-term disclosures include only those leases with a term greater than one month and 12 months or less, and expense is recognized on a straight-line basis over the lease term. Leases with an initial term of 12 months or less, that do not include an option to purchase the underlying asset that the Company is reasonably certain to exercise, are not recorded on the balance sheet.

 

Other information related to the Company’s leases is provided below.

 

    Nine Months Ended
September 30, 2019
 
Supplemental Cash Flows Information        
Cash paid for amounts included in the measurement of lease liability:        
Operating cash flows from operating lease     86,234  
Operating lease asset obtained in exchange for lease obligation:        
Operating lease   $ 198,319  
Remaining lease term        
Operating lease     1.1 years  
Discount rate        
Operating lease     6.00 %

 

Future payments under non-cancelable extended operating leases having initial or remaining terms of one year or more are as follows for the remaining fiscal year and thereafter:

 

Future minimum lease payments year ending December 31,      
2019 (remaining)   $ 30,675  
2020     103,254  
Total future minimum lease payments, undiscounted     133,929  
Less imputed interest     (4,581 )
Present value of lease liabilities   $ 129,348  
         
Operating lease liabilities reported as of September 30, 2019:        
Operating lease liabilities-current   $ 119,074  
Operating lease liabilities-non-current     10,274  
Total   $ 129,348  

Equity-linked Financial Instruments

Equity-linked Financial Instruments

 

The Company classifies outstanding common stock warrants with down-round features as equity, if the instrument would otherwise be classified in equity absent the down-round feature. The Company will recognize the value of a down-round feature when it is triggered and the warrant’s strike price has been adjusted downward, as a deemed dividend and reduction of income available to common stockholders in computing basic earnings per share.

Net Loss Per Share

Net Loss Per Share

 

The Company determines basic loss per share and diluted loss per share in accordance with the provisions of Accounting Standards Codification (“ASC”) 260, “Earnings per Share.” Basic net loss per share was calculated by dividing net loss by the weighted-average common shares outstanding during the period. Diluted net loss per share was calculated by dividing net loss by the weighted-average common shares outstanding during the period using the treasury stock method or the two-class method, whichever is more dilutive. The potentially dilutive stock options issued under the 2015 Plan (described in Note 8), Series A, B and C Convertible Preferred Stock (described in Note 6) and warrants to purchase the Company’s common stock (described in Notes 6 and 7) were not considered in the computation of diluted net loss per share because they would be anti-dilutive.

Comprehensive Income (Loss)

Comprehensive Income (Loss)

 

Comprehensive income (loss) is defined as the change in equity during a period from transactions and other events and circumstances from non-owner sources. The Company is required to record all components of comprehensive income (loss) in the financial statements in the period in which they are recognized. Net income (loss) and other comprehensive income (loss), including foreign currency translation adjustments and unrealized gains and losses on investments are reported, net of their related tax effect, to arrive at comprehensive income (loss). For the nine months ended September 30, 2019, comprehensive income consisted of unrealized gains on investments in available-for-sale debt securities. There were no unrealized gains (losses) on investments in available-for-sale debt securities and held-to-maturity debt securities for the nine months ended September 30, 2018.

Recent Accounting Pronouncements

Recent Accounting Pronouncements

 

In June 2016, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) No. 2016-13, Financial Instruments – Credit Losses (Topic 326): Measurement of Credit Losses on Financial Instruments, an amendment that modifies the measurement recognition of credit losses for most financial assets and certain other instruments. The amendment updates the guidance for measuring and recording credit losses on financial assets measured at amortized cost by replacing the “incurred loss” model with an “expected loss” model. Accordingly, these financial assets will be presented at the net amount expected to be collected. The amendment also requires that credit losses related to available-for-sale debt securities be recorded as an allowance through net income rather than reducing the carrying amount under the current, other-than-temporary-impairment model. The guidance is effective for public business entities that are SEC filers. The amendments in ASU No. 2016-13 are effective for fiscal years beginning after December 15, 2019, including interim periods within those fiscal years. For all other public business entities, the amendments in this ASU are effective for fiscal years beginning after December 15, 2020, including interim periods within those fiscal years. The Company does not expect the adoption of this guidance will have a material impact on its financial statements.

 

In August 2018, the FASB issued ASU No. 2018-13, “Fair Value Measurement (Topic 820): Disclosure Framework — Changes to the Disclosure Requirements for Fair Value Measurement”, an amendment to the accounting guidance on fair value measurements. The guidance modifies the disclosure requirements on fair value measurements, including the removal of disclosures of the amount of and reasons for transfers between Level 1 and Level 2 of the fair value hierarchy, the policy for timing of transfers between levels, and the valuation processes for Level 3 fair value measurements. The guidance also adds certain disclosure requirements related to Level 3 fair value measurements. The guidance is effective for fiscal years, and interim periods within those fiscal years, beginning after December 15, 2019. The Company does not expect the adoption of this guidance will have a material impact on its financial statements.

 

In June 2016, the FASB issued ASU 2016-13, Financial Instruments—Credit Losses (Topic 326): Measurement of Credit Losses on Financial Instruments (ASU 2016-13) and also issued subsequent amendments to the initial guidance: ASU 2018-19, ASU 2019-04, and ASU 2019-05 (collectively, “Topic 326”). Topic 326 requires measurement and recognition of expected credit losses for financial assets held. The effective date and transition methodology for the amendments in Topic 326 are the same as in ASU 2016-13. The Company does not expect the adoption of this guidance will have a material impact on its financial statements.

 

Other accounting standard updates effective after September 30, 2019 are not expected to have a material impact on the Company’s financial statements.

Recently Adopted Accounting Pronouncements

Recently Adopted Accounting Pronouncements

 

In February 2016, the FASB issued ASU No. 2016-02, Leases (Topic 842). Under this guidance, an entity is required to recognize ROU assets and corresponding lease liabilities on its balance sheets and disclose key information about leasing arrangements. In July 2018, the FASB issued ASU No. 2018-11, Leases (Topic 842) Targeted Improvements, which provides for an alternative transition method by allowing companies to continue to use the legacy guidance in Topic 840, Leases, including its disclosure requirements, in the comparative periods presented in the year of adoption of the new leases standard and recognize a cumulative-effect adjustment to the opening balance of retained earnings in the period of adoption rather than the earliest period presented.

 

The Company elected the available package of practical expedients, but not the hindsight practical expedient, and implemented internal controls to enable the preparation of financial information on adoption as of January 1, 2019.

 

The standard had a material impact on the Company’s condensed balance sheets, but did not have an impact on its statements of operations and comprehensive loss. The most significant impact was the recognition of a ROU asset and lease liability for the Company’s sole operating lease—the Company had no finance leases. Adoption of the standard did not require the Company to restate previously reported results as it elected to apply a modified retrospective approach at the beginning of the period of adoption rather than at the beginning of the earliest comparative period presented.

 

In June 2018, the FASB issued ASU No. 2018-07, Improvements to Nonemployee Share-Based Payment Accounting, which expands the scope of Topic 718 Compensation—Stock Compensation, to include share-based payments issued to nonemployees for goods or services. Consequently, the accounting for share-based payments to nonemployees and employees will be substantially aligned. ASU No. 2018-07 supersedes Subtopic 505-50 Equity—Equity-Based Payments to Non-Employees. The amendments implemented by ASU No. 2018-07 are effective for fiscal years beginning after December 15, 2018, including interim periods within that fiscal year. Early adoption is permitted, but no earlier than an entity’s adoption date of Topic 606. The Company adopted ASU 2018-07 on January 1, 2019 and it did not have a material effect on its results of operations, financial position or cash flows.

 

In August 2018, the SEC adopted final rules under SEC Release No. 33-10532, Disclosure Update and Simplification, amending certain SEC disclosure requirements that were redundant, duplicative, overlapping, outdated or superseded. In addition, the amendments expanded the disclosure requirements on the analysis of stockholders’ equity for interim financial statements. Under the amendments, an analysis of changes in each caption of stockholders’ equity presented in the balance sheets must be provided in a note or separate statement. The analysis must present a reconciliation of the beginning balance to the ending balance of each period for which a statement of comprehensive income is required to be filed. These final rules became effective on November 5, 2018, with issuers required to provide their analysis of stockholders’ equity in quarterly reports on Form 10-Q beginning with reports for the quarter ended March 31, 2019. The Company included the analysis of changes in stockholders’ equity in the interim period unaudited condensed financial statements for the quarter ended March 31, 2019, has included it in this Quarterly Report, and will continue to do so in the Company’s quarterly reports on Form 10-Q in the future. The Company adopted these SEC amendments on January 1, 2019 and it did not have a material impact on the Company’s financial position, results of operations, cash flows or stockholders’ equity.

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Subsequent Events (Details Narrative) - Subsequent Event [Member] - USD ($)
Nov. 12, 2019
Nov. 06, 2019
Sales Agreement [Member] | Private Placement [Member]    
Aggregate offering price of common stock   $ 3,673,159
Waiver Agreement [Member]    
Aggreement transaction description The terms of the Waiver Agreement, the Series B Holders agreed to waive the restriction in Section 4.12(b) of the 2018 Purchase Agreement prohibiting Dilutive Issuances (as defined in the 2018 Purchase Agreement) for the remainder of the Restricted Period (as defined in the 2018 Purchase Agreement), such that Section 4.12(b) of the 2018 Purchase Agreement is of no further force and effect (the “Waiver”). In exchange for the Series B Holders’ Waiver and subject to the other terms and conditions described in the Waiver Agreement, we agreed to reduce the conversion price of the Series B convertible preferred stock from $1.30 to $0.20 per share and to reduce the conversion price of the Series C convertible preferred stock from $1.64 to $0.20 per share, in each case subject to the approval of our stockholders to issue the additional shares of common stock that will be issuable upon conversion of the Series B convertible preferred stock and Series C convertible preferred stock as a result of the Series B Conversion Price Adjustment and the Series C Conversion Price Adjustment as required by the applicable Nasdaq rules, which stockholder approval we agreed to seek by no later than the earlier of (i) our next annual or special meeting of stockholders, or (ii) February 14, 2020.  
Waiver Agreement [Member] | Series B Convertible Preferred Stock [Member] | Maximum [Member]    
Conversion price per share $ 1.64  
Waiver Agreement [Member] | Series B Convertible Preferred Stock [Member] | Minimum [Member]    
Conversion price per share 0.20  
Waiver Agreement [Member] | Series C Convertible Preferred Stock [Member] | Maximum [Member]    
Conversion price per share 1.30  
Waiver Agreement [Member] | Series C Convertible Preferred Stock [Member] | Minimum [Member]    
Conversion price per share $ 0.20  
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Stock-Based Compensation (Details Narrative) - USD ($)
3 Months Ended 9 Months Ended
Mar. 23, 2018
Sep. 15, 2017
Jun. 02, 2017
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Expected dividend yield       0.00% 0.00% 0.00% 0.00%
Risk-free interest rate           0.00%  
Reverse split stock 1-for-10 reverse stock split       1-for-10 reverse stock    
Stock based compensation expense       $ 95,000 $ 171,000 $ 363,730 $ 561,755
Unrecognized compensation cost related to un-vested stock based compensation       $ 334,000   $ 334,000  
Weighted average period of compensation cost expected to be recognized           1 year 5 months 16 days  
Number of stock options exercised            
2015 Equity Incentive Plan [Member]              
Aggregate number of common stock shares authorized for issuance       2,750,000   2,750,000  
Number of common stock available for issuance       183,124   183,124  
2015 Equity Incentive Plan [Member] | Employee Stock Option [Member]              
Additional number of shares of common stock authorized to issue   2,585,871 83,800        
2015 Stock Plan [Member] | Employee Stock Option [Member]              
Stock option description           The exercise price for an option issued under the 2015 Plan is determined by the Board of Directors, but will be (i) in the case of an incentive stock option (A) granted to an employee who, at the time of grant of such option, is a 10% stockholder, no less than 110% of the fair market value per share on the date of grant; or (B) granted to any other employee, no less than 100% of the fair market value per share on the date of grant; and (ii) in the case of a non-statutory stock option, no less than 100% of the fair market value per share on the date of grant. The options awarded under the Plans will vest as determined by the Board of Directors but will not exceed a ten-year period.  
Vesting period of options           10 years  
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Stockholders' Equity
9 Months Ended
Sep. 30, 2019
Equity [Abstract]  
Stockholders' Equity

NOTE 6 - STOCKHOLDERS’ EQUITY

 

Authorized Shares

 

The Company’s Amended and Restated Certificate of Incorporation authorizes the issuance of up to 225,000,000 shares of common stock, $0.001 par value per share, and 15,000,000 shares of preferred stock, $0.001 par value per share, of which 9,500, 6,000 and 1,880 shares are designated for Series A, B and C, respectively.

 

All common share amounts and per share amounts were retroactively restated to reflect a 1-for-10 reverse stock split that was effective March 23, 2018.

  

As of September 30, 2019, the Company had 9,926,956 shares of common stock, 4,080 shares of Series A convertible preferred stock, 1,850 shares of Series B convertible preferred stock and 240 shares of Series C convertible preferred stock issued and outstanding. Each share of the Company’s common stock is entitled to one vote, and all shares rank equally as to voting and other matters. Each share of Series A preferred stock is convertible by the holder at $4.00 per share, subject to adjustment for stock splits, stock dividends, subsequent rights offerings, pro rata distributions, and fundamental transactions. Each share of Series B preferred stock is convertible by the holder at $1.30 per share, subject to customary adjustment in the event of future stock dividends and stock splits. Each share of Series C preferred stock is convertible by the holder at $1.64 per share, subject to customary adjustment in the event of future stock dividends and stock splits. Holders are entitled to receive, and the Company shall pay, dividends on outstanding shares of Series A, Series B and Series C preferred stock, on an as-if-converted-to-common-stock basis, equal to and in the same form as dividends actually paid on outstanding common shares when, as and if such dividends are paid on outstanding common shares. Upon any liquidation, dissolution or winding-up of the Company, whether voluntary or involuntary, the holders of Series A, Series B and Series C preferred stock shall be entitled to receive out of the assets of the Company, whether capital or surplus, the same amount that a holder of common stock would receive if the Series A, Series B and Series C preferred stock were fully converted to common stock, which amounts shall be paid pari passu with all common stockholders. Holders of Series A, Series B and Series C preferred stock have no voting rights. However, as long as any shares of Series A, Series B and Series C preferred stock are outstanding, the Company may not, without the affirmative vote of the holders of a majority of the then outstanding shares of Series A, Series B and Series C preferred stock, (a) alter or change adversely the powers, preferences or rights given to the Series A, Series B and Series C preferred stock or alter or amend the applicable Certificate of Designation, (b) amend the Company’s certificate of incorporation or other charter documents in any manner that adversely affects any rights of the holders of Series A, Series B and Series C preferred stock, (c) increase the number of authorized shares of Series A, Series B and Series C preferred stock, or (d) enter into any agreement with respect to any of the foregoing.

 

Aspire Capital Common Stock Purchase Agreement

 

On May 4, 2017, the Company entered into a common stock purchase agreement with Aspire Capital Fund, LLC (“Aspire Capital”), which the Company and Aspire amended and restated on March 29, 2019 and July 23, 2019 (as amended and restated, the “Aspire Purchase Agreement”). The Aspire Purchase Agreement was amended and restated to adjust certain provisions of the agreement to improve the Company’s access to funding under the agreement. The Aspire Purchase Agreement provides access to the Company of up to an aggregate of $6.5 million in proceeds through the sale of shares of its common stock through March 31, 2021.

 

Under the Aspire Purchase Agreement, as amended, on any trading day the Company selects, it has the right, in its sole discretion, to present Aspire Capital with a purchase notice (each, a “Purchase Notice”), directing Aspire Capital (as principal) to purchase up to 100,000 shares of its common stock per trading day for up to an aggregate of $6,500,000 of its common stock, at a per share price (the “Purchase Price”) equal to the lesser of: (i) the lowest sale price of the Company’s common stock on the sale date, or (ii) the arithmetic average of the three lowest closing sale prices for the Company’s common stock during the ten (10) consecutive trading days ending on the trading day immediately preceding the sale date. The aggregate purchase price payable by Aspire Capital on any one purchase date cannot exceed $500,000. In addition, on any date on which the Company submits a Purchase Notice to Aspire Capital in an amount of at least 100,000 shares and its stock price is not less than $0.25 per share, the Company can also, in its sole discretion, present Aspire Capital with a volume-weighted average price purchase notice (each, a “VWAP Purchase Notice”) directing Aspire Capital to purchase an amount of its common stock equal to up to 30% of the aggregate shares of the Company’s common stock traded on its principal market on the next trading day (the “VWAP Purchase Date”), as determined by the Company. Under the terms of the Aspire Purchase Agreement, the number of shares that can be sold pursuant to Aspire Capital is limited to 1,807,562 (the “Exchange Cap”), which represented 19.99% of the Company’s outstanding shares of common stock as of March 29, 2019, the date the agreement was first amended and restated, unless stockholder approval or an exception pursuant to the rules of the Nasdaq Capital Market was obtained to issue more than 19.99%. This limitation would not apply if, at any time the Exchange Cap was reached and at all times thereafter, the average price paid for all shares issued under the Aspire Purchase Agreement was equal to or greater than $0.86 (the “Minimum Price”), which was the closing price of the Company’s common stock immediately preceding the signing of the agreement. As of September 30, 2019, no shares of common stock have been sold or issued to Aspire Capital under the Aspire Purchase Agreement.

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Subsequent Events
9 Months Ended
Sep. 30, 2019
Subsequent Events [Abstract]  
Subsequent Events

NOTE 10 – SUBSEQUENT EVENTS

 

In October 2019, the Company announced that it has engaged A.G.P as financial advisor to explore and evaluate strategic alternatives to enhance shareholder value, which may include an acquisition, merger, reverse merger, other business combination, sale of assets, licensing or other strategic transactions.

 

On November 6, 2019, the Company entered into a Sales Agreement (the “ATM Agreement”) with A.G.P., pursuant to which the Company may offer and sell, from time to time through A.G.P., shares of the Company’s common stock having an aggregate offering price of up to $3,673,159 (the “Placement Shares”), subject to the terms and conditions of the ATM Agreement. Unless earlier terminated pursuant to the terms of the ATM Agreement, the ATM Agreement will automatically terminate upon the earlier to occur of (i) issuance and sale of all of the Placement Shares to or through A.G.P. and (ii) August 1, 2022.

 

On November 12, 2019, we entered into an irrevocable consent and waiver agreement (the “Waiver Agreement”) with the holders of our outstanding Series B convertible preferred stock (the “Series B Holders”), who are also parties to that certain Securities Purchase Agreement, dated as of October 30, 2018 (the “2018 Purchaser Agreement”), by and among the Company and the purchasers identified therein (including the Series B Holders). Pursuant to the terms of the Waiver Agreement, the Series B Holders agreed to waive the restriction in Section 4.12(b) of the 2018 Purchase Agreement prohibiting Dilutive Issuances (as defined in the 2018 Purchase Agreement) for the remainder of the Restricted Period (as defined in the 2018 Purchase Agreement), such that Section 4.12(b) of the 2018 Purchase Agreement is of no further force and effect (the “Waiver”). In exchange for the Series B Holders’ Waiver and subject to the other terms and conditions described in the Waiver Agreement, we agreed to reduce the conversion price of the Series B convertible preferred stock from $1.30 to $0.20 per share and to reduce the conversion price of the Series C convertible preferred stock from $1.64 to $0.20 per share, in each case subject to the approval of our stockholders to issue the additional shares of common stock that will be issuable upon conversion of the Series B convertible preferred stock and Series C convertible preferred stock as a result of the Series B Conversion Price Adjustment and the Series C Conversion Price Adjustment as required by the applicable Nasdaq rules, which stockholder approval we agreed to seek by no later than the earlier of (i) our next annual or special meeting of stockholders, or (ii) February 14, 2020.

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XML 48 R28.htm IDEA: XBRL DOCUMENT v3.19.3
Stockholders' Equity (Details Narrative)
3 Months Ended 9 Months Ended
Jul. 23, 2019
USD ($)
Mar. 29, 2019
USD ($)
shares
Mar. 23, 2018
Sep. 30, 2018
Sep. 30, 2019
USD ($)
Integer
$ / shares
shares
Dec. 31, 2018
$ / shares
shares
Common stock, shares authorized         225,000,000 225,000,000
Common stock, par value | $ / shares         $ 0.001 $ 0.001
Preferred stock, shares authorized         15,000,000  
Preferred stock, par value | $ / shares         $ 0.001  
Reverse split stock     1-for-10 reverse stock split 1-for-10 reverse stock    
Common stock, shares issued         9,926,956 6,036,562
Common stock, shares outstanding         9,926,956 6,036,562
Common stock voting, description         Each share of the Company's common stock is entitled to one vote, and all shares rank equally as to voting and other matters.  
2017 Aspire Purchase Agreement [Member]            
Number of common shares sold          
Number of common shares sold, value | $         $ 6,500,000  
Debt instrument convertible consecutive trading days | Integer         10  
Aggregate percentage of shares, direction under purchase         30.00%  
Percentage for common stock outstanding   19.99%        
2017 Aspire Purchase Agreement [Member] | Minimum [Member]            
Number of common shares sold         100,000  
Minimum number of shares to be purchased under purchase notice         100,000  
Minimum stock price under purchase notice | $ / shares         $ 0.25  
Average price paid | $ / shares         $ 0.86  
2017 Aspire Purchase Agreement [Member] | Maximum [Member]            
Maximum purchase price payable on one purchase date | $         $ 500,000  
Number of common stock may be sold   1,807,562        
Percentage for common stock outstanding   19.99%        
2017 Aspire Purchase Agreement [Member] | Aspire Capital Fund LLC [Member] | March 31, 2021 [Member]            
Proceeds from sale of common stock | $ $ 6,500,000 $ 6,500,000        
Series A Preferred Stock [Member]            
Preferred stock, shares authorized         9,500 9,500
Preferred stock, par value | $ / shares         $ 0.001 $ 0.001
Preferred stock, shares issued         4,080 4,080
Preferred stock, shares outstanding         4,080 4,080
Preferred stock convertible into common stock conversion price per share | $ / shares         $ 4.00  
Series B Preferred Stock [Member]            
Preferred stock, shares authorized         6,000 6,000
Preferred stock, par value | $ / shares         $ 0.001 $ 0.001
Preferred stock, shares issued         1,850 5,608
Preferred stock, shares outstanding         1,850 5,608
Preferred stock convertible into common stock conversion price per share | $ / shares         $ 1.30  
Series C Preferred Stock [Member]            
Preferred stock, shares authorized         1,880 1,880
Preferred stock, par value | $ / shares         $ 0.001 $ 0.001
Preferred stock, shares issued         240 1,880
Preferred stock, shares outstanding         240 1,880
Preferred stock convertible into common stock conversion price per share | $ / shares         $ 1.64  
XML 49 R20.htm IDEA: XBRL DOCUMENT v3.19.3
Stock-Based Compensation (Tables)
9 Months Ended
Sep. 30, 2019
Share-based Payment Arrangement [Abstract]  
Summary of Stock Option Activity

The following represents a summary of the options granted to employees and non-employees that are outstanding at September 30, 2019 and changes during the period then ended:

 

    Options     Weighted Average Exercise Price     Aggregate Intrinsic Value     Weighted Average Remaining Contractual
Life (in years)
 
Outstanding at December 31, 2018     673,885     $ 19.82     $ ―        8.2  
Granted     698,750     $ 0.62     $ ―        9.0  
Exercised/ Expired/ Forfeited     (28,500 )   $ 0.98     $ ―        ―   
Outstanding at September 30, 2019     1,344,135     $ 10.24     $ ―        8.4  
Exercisable at September 30, 2019     531,528     $ 28.66     $ ―        7.4  

Schedule of Assumptions Used in Black-Scholes Option-Pricing Method

The material factors incorporated in the Black-Scholes model in estimating the fair value of the options granted for the periods presented were as follows (three months ended September 30, 2018 stock price adjusted for 1-for-10 reverse stock split):

 

    For the three months ended September 30,     For the nine months ended September 30,  
    2019     2018     2019     2018  
Expected dividend yield     0.00 %     0.00 %     0.00 %     0.00 %
Expected stock-price volatility     69.00% – 69.38 %     48.89% – 50.22 %     46.33% – 69.38 %     46.47% – 53.11 %
Risk-free interest rate     1.47% – 1.54 %     2.78% – 3.07 %     1.47% – 2.60 %     2.46% – 3.07 %
Expected average term of options     5 –7       7 – 10       5 – 7       5 – 10  
Stock price   $ 1.04     $ 1.85 – $2.22     $ 0.60 – $1.04     $ 1.85 – $3.40  

Schedule of Nonvested Restricted Stock Units

The following table summarizes restricted stock unit activity for the nine months ended September 30, 2019:

 

    Number of
Units
   

Weighted Average

Grant Date

Fair Value

 
Unvested at December 31, 2018     1,100,000     $ 2.73  
Granted     35,000       0.63  
Forfeited            
Expired     (35,000 )     0.63  
Unvested at September 30, 2019     1,100,000     $ 2.73  

XML 50 R24.htm IDEA: XBRL DOCUMENT v3.19.3
Summary of Significant Accounting Policies - Schedule of Future Minimum Lease Payments Under Non-cancelable Operating Leases (Details) - USD ($)
Sep. 30, 2019
Dec. 31, 2018
Accounting Policies [Abstract]    
2019 (remaining) $ 30,675  
2020 103,254  
Total future minimum lease payments, undiscounted 133,929  
Less imputed interest (4,581)  
Present value of lease liabilities 129,348  
Operating lease liabilities-current 119,074
Operating lease liabilities-non-current 10,274
Total $ 129,348  
XML 51 R6.htm IDEA: XBRL DOCUMENT v3.19.3
Condensed Statements of Cash Flows (Unaudited) - USD ($)
9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Cash flows from operating activities    
Net loss $ (9,688,127) $ (10,243,605)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 4,550 4,257
Amortization of right-of-use assets 78,341
Stock-based compensation 363,730 561,755
Settlement of Covance accounts payable (893,823)
Amortization of discount on available-for-sale debt securities (9,769)
Unrealized gain on available-for-sale securities 923
Changes in operating assets and liabilities:    
Accrued interest receivable 52,987
Prepaid expenses (349,677) (298,384)
Other assets (10,000)
Accounts payable (1,945,831) 786,723
Accrued expenses (1,266,621) (45,692)
Lease liabilities (68,971)
Other liabilities (13,359) (1,362)
Net cash used in operating activities (12,851,824) (10,130,131)
Cash flows from (used in) investing activities    
Purchase of property and equipment (1,589) (2,008)
Sale of investments in marketable debt securities 6,998,549
Net cash flows from investing activities 6,996,960 (2,008)
Cash flows used in financing activities    
Payout to stockholders for fractional shares (3,256)
Net cash used in financing activities (3,256)
Net decrease in cash and cash equivalents (5,854,864) (10,135,395)
Cash and cash equivalents at beginning of period 7,812,259 22,631,971
Cash and cash equivalents at end of period 1,957,395 12,496,576
Supplemental disclosure of cash flow activities:    
Cash paid for taxes 187,079
Supplemental disclosure of non-cash financing activities:    
Conversion of preferred stock to common stock 4,257,975 1,784,327
Right-of-use assets obtained in exchange for lease liabilities (198,319)
Lease liabilities arising from obtaining right-of-use assets $ 184,644
XML 52 R2.htm IDEA: XBRL DOCUMENT v3.19.3
Condensed Balance Sheets - USD ($)
Sep. 30, 2019
Dec. 31, 2018
Current assets    
Cash and cash equivalents $ 1,957,395 $ 7,812,259
Accrued interest receivable 1,469 54,456
Investments in marketable securities 6,988,780
Prepaid expenses 771,199 421,522
Total current assets 2,730,063 15,277,017
Other assets    
Right-of-use assets 119,978
Other assets 32,725 22,725
Total other assets 152,703 22,725
Property and equipment, net 17,199 20,160
Total Assets 2,899,965 15,319,902
Current liabilities    
Accounts payable 2,566,485 4,512,316
Accrued expenses 141,222 1,407,843
Lease liabilities 119,074
Other liabilities 13,359
Total current liabilities 2,826,781 5,933,518
Lease liabilities, non-current 10,274
Total Liabilities 2,837,055 5,933,518
Stockholders' equity    
Common stock, $0.001 par value; 225,000,000 shares authorized, 9,926,956 and 6,036,562 shares issued and outstanding as of September 30, 2019 and December 31, 2018, respectively 9,927 6,037
Additional paid-in capital 76,122,975 71,505,160
Accumulated other comprehensive loss (923)
Accumulated deficit (79,888,272) (70,200,145)
Total stockholders' equity 62,910 9,386,384
Total Liabilities and Stockholders' Equity 2,899,965 15,319,902
Series A Preferred Stock [Member]    
Stockholders' equity    
Preferred stock, value 2,289,324 2,289,324
Series B Preferred Stock [Member]    
Stockholders' equity    
Preferred stock, value 1,288,956 3,906,931
Series C Preferred Stock [Member]    
Stockholders' equity    
Preferred stock, value $ 240,000 $ 1,880,000

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Stock-Based Compensation - Summary of Stock Option Activity (Details)
9 Months Ended
Sep. 30, 2019
USD ($)
$ / shares
shares
Share-based Payment Arrangement [Abstract]  
Number of Shares, Options Outstanding, Beginning | shares 673,885
Number of Shares, Options Granted | shares 698,750
Number of Shares, Options Exercised/ Expired/ Forfeited | shares (28,500)
Number of Shares, Options Outstanding at Ending | shares 1,344,135
Number of Shares, Options Exercisable | shares 531,528
Weighted Average Exercise Price, Outstanding, Beginning $ 19.82
Weighted Average Exercise Price, Options Granted 0.62
Weighted Average Exercise Price, Options Exercised/ Expired/ Forfeited 0.98
Weighted Average Exercise Price, Outstanding at Ending 10.24
Weighted Average Exercise Price, Options Exercisable $ 28.66
Aggregate Intrinsic Value, Outstanding, Beginning | $
Aggregate Intrinsic Value, Options Granted
Aggregate Intrinsic Value, Options Exercised/ Expired/ Forfeited
Aggregate Intrinsic Value, Outstanding at Ending | $
Aggregate Intrinsic Value, Options Exercisable | $
Weighted- Average Remaining Contractual Life (in Years), Outstanding, Beginning 8 years 2 months 12 days
Weighted- Average Remaining Contractual Life (in Years), Options Granted 9 years
Weighted- Average Remaining Contractual Life (in Years), Outstanding at Ending 8 years 4 months 24 days
Weighted- Average Remaining Contractual Life (in Years), Options Exercisable 7 years 4 months 24 days